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Protein

Xylose isomerase

Gene

xylA

Organism
Fibrella aestuarina BUZ 2
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei111 – 1111UniRule annotation
Active sitei114 – 1141UniRule annotation
Metal bindingi242 – 2421Magnesium 1UniRule annotation
Metal bindingi278 – 2781Magnesium 1UniRule annotation
Metal bindingi278 – 2781Magnesium 2UniRule annotation
Metal bindingi281 – 2811Magnesium 2UniRule annotation
Metal bindingi306 – 3061Magnesium 1UniRule annotation
Metal bindingi317 – 3171Magnesium 2UniRule annotation
Metal bindingi319 – 3191Magnesium 2UniRule annotation
Metal bindingi349 – 3491Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciFAES1166018-WGS:GSNK-689-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:FAES_0682Imported
OrganismiFibrella aestuarina BUZ 2Imported
Taxonomic identifieri1166018 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeFibrella
ProteomesiUP000011058 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I0K3J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQINLTLGD KAYFPFVEKP IAYEGRDSDN PLAFKFYNPA QTIMGMPMKD
60 70 80 90 100
LFRFAVAYWH TFCGTGADPF GPGVKHFPWD AGKDPLGAAF QKADAAFEFI
110 120 130 140 150
TKMGIEYYCF HDVDVAPEGD SNHDFESNFR KVVDYLKQKQ QASGVNLLWG
160 170 180 190 200
TANLFSHERY MNGASTNPDF HVLAHGAWQV KNAIDATIEL GGRGYTFWGG
210 220 230 240 250
REGYMSLLNT NMKREQEHLG RFLQVSRDYA RKQGFKGAFY IEPKPMEPTK
260 270 280 290 300
HQYDFDAATV VGFLNKYGLQ DDFELNLETN HATLANHTFA HELQVAVDNN
310 320 330 340 350
MLGSIDANRG DYQNGWDTDQ FPVDVYELTE AMLVILEAGG FKSGGVNFDA
360 370 380 390 400
KTRRNSTDLD DIFIAHIGGM DTFARAAIAA EAILTKSKYK QLRTDRYASY
410 420 430 440
DSGAGADFEA GKLTLEDLRQ YAIDNGEAKQ VSGKQELYEM IVNQYI
Length:446
Mass (Da):50,093
Last modified:June 13, 2012 - v1
Checksum:i51479EE2B97EF29C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE796683 Genomic DNA. Translation: CCG98693.1.
RefSeqiWP_015329793.1. NC_020054.1.
YP_007319286.1. NC_020054.1.

Genome annotation databases

EnsemblBacteriaiCCG98693; CCG98693; FAES_0682.
KEGGifae:FAES_0682.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE796683 Genomic DNA. Translation: CCG98693.1.
RefSeqiWP_015329793.1. NC_020054.1.
YP_007319286.1. NC_020054.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCG98693; CCG98693; FAES_0682.
KEGGifae:FAES_0682.

Phylogenomic databases

KOiK01805.

Enzyme and pathway databases

BioCyciFAES1166018-WGS:GSNK-689-MONOMER.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome Sequence of Fibrella aestuarina BUZ 2T, a Filamentous Marine Bacterium."
    Filippini M., Qi W., Blom J., Goesmann A., Smits T.H., Bagheri H.C.
    J. Bacteriol. 194:3555-3555(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BUZ 2Imported.

Entry informationi

Entry nameiI0K3J0_9BACT
AccessioniPrimary (citable) accession number: I0K3J0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: April 1, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.