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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Halobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / NBRC 102448/ NCIMB 2269) (Sporosarcina halophila)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei150 – 1501UniRule annotation
Active sitei577 – 5771UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciHHAL866895:GLDT-798-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:HBHAL_1767Imported
OrganismiHalobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / NBRC 102448/ NCIMB 2269) (Sporosarcina halophila)Imported
Taxonomic identifieri866895 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeHalobacillus
ProteomesiUP000007397 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.

Sequencei

Sequence statusi: Complete.

I0JJ14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNQPKTNDH TTPLRRDINE LGKMLGNLLV HHGGEELLNK VETIRQLTKD
60 70 80 90 100
LRNNHSTSTY NQLKEEIQNL KPPMRSQVIR AFSIYFHLVN IAEQNHRIRR
110 120 130 140 150
RREYQLREDH GAQPFSLESA VLNLKNNNFS KDVIQNVLDH LSLELIITAH
160 170 180 190 200
PTEATKRTVL EIQKRIATIL QKLDNPQLTK NERDSLKDSL QNEVSVLWQT
210 220 230 240 250
DELRDRKPTV MDEVRNGLYY FDETLFDVLP EIHQELEYCL EENYPEEDWD
260 270 280 290 300
VPNFLRFGSW IGGDRDGNPN VTPDITWQTL QKQRNLVLNK YEEVLVELMK
310 320 330 340 350
RFSHSSAQVT VTDELMASIE KEEPQLPKGK KWRVEKEIYR RKFAIVLERL
360 370 380 390 400
RQVGQSDLGY DYADELLEDL YQIQKSAKTH QPARRELKKL RKLIRQVELF
410 420 430 440 450
GFHLATLDIR NHSGEHESAV DELLRKVSIE DNYSELAEDK KIEVLQNVLK
460 470 480 490 500
DPRPISLLNE DYSDSTQEML TVFQMIRNAH IEFGKRSIEV YLISMTESAS
510 520 530 540 550
DLLEVLVLAK EAGIYRLHAD GTVESNINVA PLLETVDDLV AGPEILKTLF
560 570 580 590 600
EMDVYAKHLK HRNNHQEIML GYSDGSKDGG TLTANWRLYK AQQEIHTMAR
610 620 630 640 650
EYNVGLKFFH GRGGSLGRGG GPLNRSLLSQ PEETLGDGVK ITEQGEVLSS
660 670 680 690 700
RYLIKDIAYR SLEQGASTLL EGAANVSQES EQAHNREDAW EQAMEEIAEI
710 720 730 740 750
SLKKYQSLVF GDKDFLTYFN EATPLKEISE LNIGSRPMKR KDSSKFENLR
760 770 780 790 800
AIPWVFAWSQ NRQLIPAWYA AGSGLASYVE NDNDRLEQLK QMYINWPFFR
810 820 830 840 850
STINNLQMAL TKADIQTAQE YTQLVNDQEL GERIFNNIVD EYERTKEILL
860 870 880 890 900
KISGDEELLT HQPTIKESVR LRNPYVDPLN FLQVELIKEL RASEDQDDEL
910
LTEVLLTISG IAAGLRNTG
Length:919
Mass (Da):106,039
Last modified:June 13, 2012 - v1
Checksum:i00216DEAAA6B1FAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE717023 Genomic DNA. Translation: CCG44132.1.
RefSeqiYP_006179409.1. NC_017668.1.

Genome annotation databases

EnsemblBacteriaiCCG44132; CCG44132; HBHAL_1767.
KEGGihhd:HBHAL_1767.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE717023 Genomic DNA. Translation: CCG44132.1.
RefSeqiYP_006179409.1. NC_017668.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCG44132; CCG44132; HBHAL_1767.
KEGGihhd:HBHAL_1767.

Phylogenomic databases

KOiK01595.

Enzyme and pathway databases

BioCyciHHAL866895:GLDT-798-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Chloride and organic osmolytes: a hybrid strategy to cope with elevated salinities by the moderately halophilic, chloride-dependent bacterium Halobacillus halophilus."
    Saum S.H., Pfeiffer F., Palm P., Rampp M., Schuster S.C., Muller V., Oesterhelt D.
    Environ. Microbiol. 15:1619-1633(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35676 / DSM 2266 / JCM 20832 / NBRC 102448/ NCIMB 2269Imported.

Entry informationi

Entry nameiI0JJ14_HALH3
AccessioniPrimary (citable) accession number: I0JJ14
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: April 29, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.