ID   I0IRW2_LEPFC            Unreviewed;       412 AA.
AC   I0IRW2;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Pyruvate synthase, alpha subunit {ECO:0000313|EMBL:BAM08011.1};
GN   OrderedLocusNames=LFE_2339 {ECO:0000313|EMBL:BAM08011.1};
OS   Leptospirillum ferrooxidans (strain C2-3).
OC   Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC   Leptospirillum.
OX   NCBI_TaxID=1162668 {ECO:0000313|EMBL:BAM08011.1, ECO:0000313|Proteomes:UP000007382};
RN   [1] {ECO:0000313|EMBL:BAM08011.1, ECO:0000313|Proteomes:UP000007382}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C2-3 {ECO:0000313|EMBL:BAM08011.1,
RC   ECO:0000313|Proteomes:UP000007382};
RX   PubMed=22815442; DOI=10.1128/JB.00696-12;
RA   Fujimura R., Sato Y., Nishizawa T., Oshima K., Kim S.-W., Hattori M.,
RA   Kamijo T., Ohta H.;
RT   "Complete Genome Sequence of Leptospirillum ferrooxidans Strain C2-3,
RT   Isolated from a Fresh Volcanic Ash Deposit on the Island of Miyake,
RT   Japan.";
RL   J. Bacteriol. 194:4122-4123(2012).
RN   [2] {ECO:0000313|Proteomes:UP000007382}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C2-3 {ECO:0000313|Proteomes:UP000007382};
RA   Fujimura R., Sato Y., Nishizawa T., Nanba K., Oshima K., Hattori M.,
RA   Kamijo T., Ohta H.;
RT   "The complete genome sequence of the pioneer microbe on fresh volcanic
RT   deposit, Leptospirillum ferrooxidans strain C2-3.";
RL   Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP012342; BAM08011.1; -; Genomic_DNA.
DR   AlphaFoldDB; I0IRW2; -.
DR   STRING; 1162668.LFE_2339; -.
DR   KEGG; lfc:LFE_2339; -.
DR   PATRIC; fig|1162668.3.peg.2780; -.
DR   eggNOG; COG0674; Bacteria.
DR   HOGENOM; CLU_002569_5_0_0; -.
DR   OrthoDB; 9794954at2; -.
DR   Proteomes; UP000007382; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR033412; PFOR_II.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF17147; PFOR_II; 1.
DR   Pfam; PF01855; POR_N; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Pyruvate {ECO:0000313|EMBL:BAM08011.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007382}.
FT   DOMAIN          58..277
FT                   /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT                   pyrimidine binding"
FT                   /evidence="ECO:0000259|Pfam:PF01855"
FT   DOMAIN          301..380
FT                   /note="Pyruvate:ferredoxin oxidoreductase core"
FT                   /evidence="ECO:0000259|Pfam:PF17147"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   412 AA;  45426 MW;  4514CB74576C6D38 CRC64;
     MSEGAGVEVK PTSAGAGVVK ESETSEAAKQ KVVTPEYMFF EAPRERAFIT GSEAAKEAIR
     RANVDVAISY PITPQSETMQ QVGALWAEGY VKEYYRGEEE IGVMSAIAGS SRAGARSLTA
     TAGPGLMRGM EVVASWPGGR MPIVLLIMCR VINAPLSIQP DNAELAYLIN TGNIVFHAEN
     QQDFFDYTLK AFIISERPEV TLPVAVAVDG FFVTHARGYV MMPSKDIKLP PRDPYHEAVP
     VMDNENPPAR LSRDAPIQKS NFISYHVHAS WQQEVWAAVE RSRKYIDLYM GGLVEIVNPD
     ADTIVIASGS AVSQSREAVR QAEEDLGERI GLIKIRSLRP FPTKELRDAC KNAKRIIVPE
     FNCVGWLYRD VAAALYGYSK AEIIPGPRVF GGISLPTEMI LQYIFPDKKF VF
//