I0IMF5 (I0IMF5_LEPFC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

Ordered Locus Names:

LFE_0739 EMBL BAM06454.1

Organism

Leptospirillum ferrooxidans (strain C2-3) [Complete proteome] [HAMAP] EMBL BAM06454.1

Taxonomic identifier

1162668 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Nitrospirae › Nitrospira › Nitrospirales › Nitrospiraceae › Leptospirillum › Leptospirillum sp. Group I › Leptospirillum ferrooxidans

Protein attributes

Sequence length	620 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617 EMBL BAM06454.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	I0IMF5 [UniParc]. Last modified June 13, 2012. Version 1. Checksum: BE0E0FF6920BA43C	FASTA	620	68,987
	10 20 30 40 50 60 MGFCIDEISE DFSKMEAIKG RTELAGILGN LFLRCDEEEI APLVYVVQGQ LSPPFRGEPM 70 80 90 100 110 120 GMASRLLIRA LSEVKAKKTF SDLNPEEAKK MEKSLDVMLA HLGDPGALAQ EVLSQNSPSR 130 140 150 160 170 180 LSFLDVFRIL ERLSQMEGEG SQVDKVSELA TLLSRLSPLS ARFVARFVMG KLRLGVGDST 190 200 210 220 230 240 IIEALAVSGG GRATKSIVEK AYNICSDLGL VGRKIKQGGL ESLSSLEPSP GFPIRVALCE 250 260 270 280 290 300 RLSSGEDIIA KIGRCSIESK YDGFRCQIHI IAGKVEIFSR NLDSMTSMFP EIVRATKEIF 310 320 330 340 350 360 GNRSAIFEGE ALGIDPETGT YQPFQVTITR KRKHNVLEKS LEIPLRLLVF DLLYLDGVSW 370 380 390 400 410 420 MERPFFERRA KVETLFGAEK FDILEVERPP AGVIGSSRLI FTDEASKVNE FFEEVVEEGF 430 440 450 460 470 480 EGIIAKRLDG IYTAGSRNFN WIKLKKSYQG KISDTLDLVI IGYYLGKGQR LKLGIGAILA 490 500 510 520 530 540 AVWDRDSKSF ASIARIGSGL TEEKWMMLSA MLREIVVPER PVDVMSDVVP DFWVLPRFVV 550 560 570 580 590 600 TVRADEISRS SMHAAGRDYL SNTEGTPEGY ALRFPRMVSF VRADKKPEDA TEVSEIVSLF 610 620 DLQRSLSQRS QREKPSSVRK

References

[1]

"Complete Genome Sequence of Leptospirillum ferrooxidans Strain C2-3, Isolated from a Fresh Volcanic Ash Deposit on the Island of Miyake, Japan." Fujimura R., Sato Y., Nishizawa T., Oshima K., Kim S.-W., Hattori M., Kamijo T., Ohta H. J. Bacteriol. 194:4122-4123(2012) Cited for: NUCLEOTIDE SEQUENCE. Strain: C2-3 EMBL BAM06454.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP012342 Genomic DNA. Translation: BAM06454.1.
RefSeq	YP_005468584.1. NC_017094.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAM06454; BAM06454; LFE_0739.
GeneID	12055547.
KEGG	lfc:LFE_0739.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K10747.
Enzyme and pathway databases
BioCyc	LFER1162668:GLFM-737-MONOMER.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit.
InterPro	IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

I0IMF5_LEPFC

Accession

Primary (citable) accession number: I0IMF5

Entry history

Integrated into UniProtKB/TrEMBL:	June 13, 2012
Last sequence update:	June 13, 2012
Last modified:	May 29, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)