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Protein
Submitted name:

Isocitrate dehydrogenase

Gene

icd

Organism
Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: InterPro
  2. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciPMIK1142394:GLIF-3201-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:PSMK_31520Imported
OrganismiPhycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01)Imported
Taxonomic identifieri1142394 [NCBI]
Taxonomic lineageiBacteriaPlanctomycetesPhycisphaeraePhycisphaeralesPhycisphaeraceaePhycisphaera
ProteomesiUP000007881: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I0IJ73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAHGDGIG PEIMDATLRV LDAAGAGLVY DTIEIGKKVY ERGVSAGIEA
60 70 80 90 100
SSWDTLRKHR VFLKAPITTP QGGGYKSLNV TTRKTLGLYA NVRPCVAYAP
110 120 130 140 150
FVGSRHPGMD VVIVRENEED TYGGIEHRQT AEVTQCLKLI SRPGCEKIVR
160 170 180 190 200
HAFEYARAAG RKRVSCFTKD NIMKATDGLF HRVFDEIRGE YPEIESDHWI
210 220 230 240 250
IDIGAAMLAD RPERFDVILT LNLYGDVLSD IAAQIAGSVG LCGTSNIGDT
260 270 280 290 300
CSMFEAIHGS APDIAGRDVA NPTGLLLAAV QMLVHLNKPG AAEKIHNAVL
310 320 330 340 350
RTIEDGVHTA DLHDGRGHDP VGTRAFADAV IQRLGQRPEH LPAAVYAGVA
360 370 380 390 400
DRAAPGVGPA TREKPVKALV GVDVFLDWDP AERDPDALAA ELHAAADGQP
410 420 430 440 450
LQLQMITNRG VKVWPEGFPE TFCTDHWRCR FVPRGGGEAS HRQVLGLLTR
460 470
LADAGLDFIK TEHLCTFDGE AGFSLGQGQ
Length:479
Mass (Da):51,658
Last modified:June 13, 2012 - v1
Checksum:i198092E781DCB762
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012338 Genomic DNA. Translation: BAM05311.1.
RefSeqiWP_014438515.1. NC_017080.1.
YP_005447208.1. NC_017080.1.

Genome annotation databases

EnsemblBacteriaiBAM05311; BAM05311; PSMK_31520.
GeneIDi12036986.
KEGGiphm:PSMK_31520.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012338 Genomic DNA. Translation: BAM05311.1.
RefSeqiWP_014438515.1. NC_017080.1.
YP_005447208.1. NC_017080.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAM05311; BAM05311; PSMK_31520.
GeneIDi12036986.
KEGGiphm:PSMK_31520.

Phylogenomic databases

KOiK00031.

Enzyme and pathway databases

BioCyciPMIK1142394:GLIF-3201-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Phycisphaera mikurensis NBRC 102666."
    Ankai A., Hosoyama A., Terui Y., Sekine M., Fukai R., Kato Y., Nakamura S., Yamada-Narita S., Kawakoshi A., Fukunaga Y., Yamazaki S., Fujita N.
    Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NBRC 102666 / KCTC 22515 / FYK2301M01Imported.

Entry informationi

Entry nameiI0IJ73_PHYMF
AccessioniPrimary (citable) accession number: I0IJ73
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: January 7, 2015
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.