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I0ICX5

- I0ICX5_PHYMF

UniProt

I0ICX5 - I0ICX5_PHYMF

Protein

Alanine racemase

Gene

alr

Organism
Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (13 Jun 2012)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei39 – 391Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei140 – 1401SubstrateUniRule annotation
    Active sitei271 – 2711Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei319 – 3191Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciPMIK1142394:GLIF-966-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:PSMK_09540Imported
    OrganismiPhycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01)Imported
    Taxonomic identifieri1142394 [NCBI]
    Taxonomic lineageiBacteriaPlanctomycetesPhycisphaeraePhycisphaeralesPhycisphaeraceaePhycisphaera
    ProteomesiUP000007881: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei39 – 391N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliI0ICX5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    I0ICX5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAPPTSNSW LEVDLAAVEA NARVLAAAAP AASLCGVVKK DAYGLGGPAV    50
    GRALEAAGAG MLAVYEPREA LAIAEAGVGL PFLVLHGTLA AGDPWAALAE 100
    AGRLEFQAGD GELLDALDAE GRRRGIRLPV HVHADTGMSR EGMPGPAAVD 150
    AVRGIPARAG LRLAGVMTHL ATADSDARRA AGQVAAFDRL LAQMELPEHA 200
    VVHLCNSYAA MREPAWHRRM IRPGIGLYGY AEPTLDRGER WETDARLRPV 250
    ARWVSRIARV LDASAGAPVG YGATESLEKD TRLGLVPVGY ADGYPLALSG 300
    RGVVRVGGAE CRVVGRVSMD QVMVDLSAAP GAGPGAEVEV YGNDPAAPNA 350
    LPRMAAAAGS HAYELLTRIH PRVERRHAVA RPGFGDPPDA G 391
    Length:391
    Mass (Da):40,577
    Last modified:June 13, 2012 - v1
    Checksum:i894F03151D73BD77
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012338 Genomic DNA. Translation: BAM03113.1.
    RefSeqiYP_005445010.1. NC_017080.1.

    Genome annotation databases

    EnsemblBacteriaiBAM03113; BAM03113; PSMK_09540.
    GeneIDi12037444.
    KEGGiphm:PSMK_09540.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012338 Genomic DNA. Translation: BAM03113.1 .
    RefSeqi YP_005445010.1. NC_017080.1.

    3D structure databases

    ProteinModelPortali I0ICX5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAM03113 ; BAM03113 ; PSMK_09540 .
    GeneIDi 12037444.
    KEGGi phm:PSMK_09540.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci PMIK1142394:GLIF-966-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Phycisphaera mikurensis NBRC 102666."
      Ankai A., Hosoyama A., Terui Y., Sekine M., Fukai R., Kato Y., Nakamura S., Yamada-Narita S., Kawakoshi A., Fukunaga Y., Yamazaki S., Fujita N.
      Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NBRC 102666 / KCTC 22515 / FYK2301M01Imported.

    Entry informationi

    Entry nameiI0ICX5_PHYMF
    AccessioniPrimary (citable) accession number: I0ICX5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 13, 2012
    Last sequence update: June 13, 2012
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3