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I0ICX5

- I0ICX5_PHYMF

UniProt

I0ICX5 - I0ICX5_PHYMF

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Protein

Alanine racemase

Gene

alr

Organism
Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei140 – 1401SubstrateUniRule annotation
Active sitei271 – 2711Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei319 – 3191Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPMIK1142394:GLIF-966-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:PSMK_09540Imported
OrganismiPhycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01)Imported
Taxonomic identifieri1142394 [NCBI]
Taxonomic lineageiBacteriaPlanctomycetesPhycisphaeraePhycisphaeralesPhycisphaeraceaePhycisphaera
ProteomesiUP000007881: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei39 – 391N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliI0ICX5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

I0ICX5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAAPPTSNSW LEVDLAAVEA NARVLAAAAP AASLCGVVKK DAYGLGGPAV
60 70 80 90 100
GRALEAAGAG MLAVYEPREA LAIAEAGVGL PFLVLHGTLA AGDPWAALAE
110 120 130 140 150
AGRLEFQAGD GELLDALDAE GRRRGIRLPV HVHADTGMSR EGMPGPAAVD
160 170 180 190 200
AVRGIPARAG LRLAGVMTHL ATADSDARRA AGQVAAFDRL LAQMELPEHA
210 220 230 240 250
VVHLCNSYAA MREPAWHRRM IRPGIGLYGY AEPTLDRGER WETDARLRPV
260 270 280 290 300
ARWVSRIARV LDASAGAPVG YGATESLEKD TRLGLVPVGY ADGYPLALSG
310 320 330 340 350
RGVVRVGGAE CRVVGRVSMD QVMVDLSAAP GAGPGAEVEV YGNDPAAPNA
360 370 380 390
LPRMAAAAGS HAYELLTRIH PRVERRHAVA RPGFGDPPDA G
Length:391
Mass (Da):40,577
Last modified:June 13, 2012 - v1
Checksum:i894F03151D73BD77
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012338 Genomic DNA. Translation: BAM03113.1.
RefSeqiWP_014436332.1. NC_017080.1.
YP_005445010.1. NC_017080.1.

Genome annotation databases

EnsemblBacteriaiBAM03113; BAM03113; PSMK_09540.
GeneIDi12037444.
KEGGiphm:PSMK_09540.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012338 Genomic DNA. Translation: BAM03113.1 .
RefSeqi WP_014436332.1. NC_017080.1.
YP_005445010.1. NC_017080.1.

3D structure databases

ProteinModelPortali I0ICX5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAM03113 ; BAM03113 ; PSMK_09540 .
GeneIDi 12037444.
KEGGi phm:PSMK_09540.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci PMIK1142394:GLIF-966-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Phycisphaera mikurensis NBRC 102666."
    Ankai A., Hosoyama A., Terui Y., Sekine M., Fukai R., Kato Y., Nakamura S., Yamada-Narita S., Kawakoshi A., Fukunaga Y., Yamazaki S., Fujita N.
    Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NBRC 102666 / KCTC 22515 / FYK2301M01Imported.

Entry informationi

Entry nameiI0ICX5_PHYMF
AccessioniPrimary (citable) accession number: I0ICX5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: October 29, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3