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I0I3V7

- I0I3V7_CALAS

UniProt

I0I3V7 - I0I3V7_CALAS

Protein

Acetylornithine aminotransferase

Gene

gabT

Organism
Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (13 Jun 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.UniRule annotation

    Cofactori

    Binds 1 pyridoxal phosphate per subunit.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei153 – 1531Pyridoxal phosphate; via carbonyl oxygenUniRule annotation
    Binding sitei156 – 1561N2-acetyl-L-ornithineUniRule annotation
    Binding sitei320 – 3201Pyridoxal phosphateUniRule annotation

    GO - Molecular functioni

    1. N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. arginine biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    AminotransferaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Arginine biosynthesisUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciCAER926550:GLA5-1942-MONOMER.
    UniPathwayiUPA00068; UER00109.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetylornithine aminotransferaseUniRule annotation (EC:2.6.1.11UniRule annotation)
    Short name:
    ACOATUniRule annotation
    Gene namesi
    Name:gabTImported
    Synonyms:argDUniRule annotation
    Ordered Locus Names:CLDAP_19050Imported
    OrganismiCaldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1)Imported
    Taxonomic identifieri926550 [NCBI]
    Taxonomic lineageiBacteriaChloroflexiCaldilineaeCaldilinealesCaldilineaceaeCaldilinea
    ProteomesiUP000007880: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei292 – 2921N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni126 – 1272Pyridoxal phosphate bindingUniRule annotation
    Regioni263 – 2664Pyridoxal phosphate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.UniRule annotation

    Phylogenomic databases

    KOiK00823.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    HAMAPiMF_01107. ArgD_aminotrans_3.
    InterProiIPR004636. AcOrn/SuccOrn_fam.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PANTHERiPTHR11986. PTHR11986. 1 hit.
    PfamiPF00202. Aminotran_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.
    PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I0I3V7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLATHLTRTI PRLNTPGPKA RAILERDRAV VSRAYGRVAD FVMSHGLGSQ    50
    VWDVDGNRYL DFMSGIAVNA TGHSHPRVVR AIQEQAEKFL HISSDYYHES 100
    WVRLSERLNE IAPFAEPSSV FLGNSGTEAV EGAIKLARYH TGRPYFLGFI 150
    GGFHGRTLGS LGFTASKITQ RRGFLPQREV IHVPYPYEYR PLLAMQPGEA 200
    DYGETVVNYI ERVVFKNLVA PDEVAAVVVE PIQGEGGYVV PPASFFPRLR 250
    ELCDRHGILL IVDEVQSGMG RTGKWWAIEH WGVEPDIVCT AKGIASGVPL 300
    GGFIARQRIA TWPTGAHGNT YGGNPLAMVA ALATMEVLEN GGIQNAAEQG 350
    AYMLSRLNEM AARHPSIGDV RGKGLMIGVE FVQDKATRMP NARLRDRIVE 400
    LAFEHGLLIM GCGVSTMRII PPLIITRPEV DEGLEIFEYA VTLAEEELMG 450
    Length:450
    Mass (Da):49,486
    Last modified:June 13, 2012 - v1
    Checksum:i9F9049CDA32C8B7F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012337 Genomic DNA. Translation: BAL99944.1.
    RefSeqiYP_005441842.1. NC_017079.1.

    Genome annotation databases

    EnsemblBacteriaiBAL99944; BAL99944; CLDAP_19050.
    GeneIDi12033791.
    KEGGicap:CLDAP_19050.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012337 Genomic DNA. Translation: BAL99944.1 .
    RefSeqi YP_005441842.1. NC_017079.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAL99944 ; BAL99944 ; CLDAP_19050 .
    GeneIDi 12033791.
    KEGGi cap:CLDAP_19050.

    Phylogenomic databases

    KOi K00823.

    Enzyme and pathway databases

    UniPathwayi UPA00068 ; UER00109 .
    BioCyci CAER926550:GLA5-1942-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    HAMAPi MF_01107. ArgD_aminotrans_3.
    InterProi IPR004636. AcOrn/SuccOrn_fam.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    PANTHERi PTHR11986. PTHR11986. 1 hit.
    Pfami PF00202. Aminotran_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Caldilinea aerophila DSM 14535 (= NBRC 102666)."
      Oguchi A., Hosoyama A., Sekine M., Fukai R., Kato Y., Nakamura S., Hanada S., Yamazaki S., Fujita N.
      Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1Imported.

    Entry informationi

    Entry nameiI0I3V7_CALAS
    AccessioniPrimary (citable) accession number: I0I3V7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 13, 2012
    Last sequence update: June 13, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Miscellaneous

    May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.UniRule annotation

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3