SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

I0I3V7

- I0I3V7_CALAS

UniProt

I0I3V7 - I0I3V7_CALAS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Acetylornithine aminotransferase
Gene
gabT, argD, CLDAP_19050
Organism
Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.UniRule annotation

Cofactori

Binds 1 pyridoxal phosphate per subunit By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei153 – 1531Pyridoxal phosphate; via carbonyl oxygen By similarityUniRule annotation
Binding sitei156 – 1561N2-acetyl-L-ornithine By similarityUniRule annotation
Binding sitei320 – 3201Pyridoxal phosphate By similarityUniRule annotation

GO - Molecular functioni

  1. N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesisUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciCAER926550:GLA5-1942-MONOMER.
UniPathwayiUPA00068; UER00109.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetylornithine aminotransferaseUniRule annotation (EC:2.6.1.11UniRule annotation)
Short name:
ACOATUniRule annotation
Gene namesi
Name:gabTImported
Synonyms:argDUniRule annotation
Ordered Locus Names:CLDAP_19050Imported
OrganismiCaldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1)Imported
Taxonomic identifieri926550 [NCBI]
Taxonomic lineageiBacteriaChloroflexiCaldilineaeCaldilinealesCaldilineaceaeCaldilinea
ProteomesiUP000007880: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei292 – 2921N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni126 – 1272Pyridoxal phosphate binding By similarityUniRule annotation
Regioni263 – 2664Pyridoxal phosphate binding By similarityUniRule annotation

Sequence similaritiesi

Phylogenomic databases

KOiK00823.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPiMF_01107. ArgD_aminotrans_3.
InterProiIPR004636. AcOrn/SuccOrn_fam.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I0I3V7-1 [UniParc]FASTAAdd to Basket

« Hide

MLATHLTRTI PRLNTPGPKA RAILERDRAV VSRAYGRVAD FVMSHGLGSQ    50
VWDVDGNRYL DFMSGIAVNA TGHSHPRVVR AIQEQAEKFL HISSDYYHES 100
WVRLSERLNE IAPFAEPSSV FLGNSGTEAV EGAIKLARYH TGRPYFLGFI 150
GGFHGRTLGS LGFTASKITQ RRGFLPQREV IHVPYPYEYR PLLAMQPGEA 200
DYGETVVNYI ERVVFKNLVA PDEVAAVVVE PIQGEGGYVV PPASFFPRLR 250
ELCDRHGILL IVDEVQSGMG RTGKWWAIEH WGVEPDIVCT AKGIASGVPL 300
GGFIARQRIA TWPTGAHGNT YGGNPLAMVA ALATMEVLEN GGIQNAAEQG 350
AYMLSRLNEM AARHPSIGDV RGKGLMIGVE FVQDKATRMP NARLRDRIVE 400
LAFEHGLLIM GCGVSTMRII PPLIITRPEV DEGLEIFEYA VTLAEEELMG 450
Length:450
Mass (Da):49,486
Last modified:June 13, 2012 - v1
Checksum:i9F9049CDA32C8B7F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012337 Genomic DNA. Translation: BAL99944.1.
RefSeqiYP_005441842.1. NC_017079.1.

Genome annotation databases

EnsemblBacteriaiBAL99944; BAL99944; CLDAP_19050.
GeneIDi12033791.
KEGGicap:CLDAP_19050.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012337 Genomic DNA. Translation: BAL99944.1 .
RefSeqi YP_005441842.1. NC_017079.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAL99944 ; BAL99944 ; CLDAP_19050 .
GeneIDi 12033791.
KEGGi cap:CLDAP_19050.

Phylogenomic databases

KOi K00823.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00109 .
BioCyci CAER926550:GLA5-1942-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPi MF_01107. ArgD_aminotrans_3.
InterProi IPR004636. AcOrn/SuccOrn_fam.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Caldilinea aerophila DSM 14535 (= NBRC 102666)."
    Oguchi A., Hosoyama A., Sekine M., Fukai R., Kato Y., Nakamura S., Hanada S., Yamazaki S., Fujita N.
    Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1.

Entry informationi

Entry nameiI0I3V7_CALAS
AccessioniPrimary (citable) accession number: I0I3V7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: September 3, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis By similarity.UniRule annotation

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi