Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

I0HVA8

- I0HVA8_RUBGI

UniProt

I0HVA8 - I0HVA8_RUBGI

Protein

Ribulose bisphosphate carboxylase large chain

Gene

cbbL

Organism
Rubrivivax gelatinosus (strain NBRC 100245 / IL144)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (13 Jun 2012)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.UniRule annotation

    Catalytic activityi

    2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
    3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

    Cofactori

    Binds 1 magnesium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei132 – 1321Substrate; in homodimeric partnerUniRule annotation
    Binding sitei182 – 1821SubstrateUniRule annotation
    Active sitei184 – 1841Proton acceptorUniRule annotation
    Binding sitei186 – 1861SubstrateUniRule annotation
    Metal bindingi210 – 2101Magnesium; via carbamate groupUniRule annotation
    Metal bindingi212 – 2121MagnesiumUniRule annotation
    Metal bindingi213 – 2131MagnesiumUniRule annotation
    Active sitei302 – 3021Proton acceptorUniRule annotation
    Binding sitei303 – 3031SubstrateUniRule annotation
    Binding sitei335 – 3351SubstrateUniRule annotation
    Sitei342 – 3421Transition state stabilizerUniRule annotation
    Binding sitei387 – 3871SubstrateUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. monooxygenase activity Source: UniProtKB-KW
    3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. reductive pentose-phosphate cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    LyaseUniRule annotationImported, MonooxygenaseUniRule annotation, Oxidoreductase

    Keywords - Biological processi

    Calvin cycleUniRule annotation, Carbon dioxide fixationUniRule annotation, PhotosynthesisUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciRGEL983917:GLJR-3646-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribulose bisphosphate carboxylase large chainUniRule annotation (EC:4.1.1.39UniRule annotation)
    Short name:
    RuBisCO large subunitUniRule annotation
    Gene namesi
    Name:cbbLUniRule annotationImported
    Ordered Locus Names:RGE_36060Imported
    OrganismiRubrivivax gelatinosus (strain NBRC 100245 / IL144)Imported
    Taxonomic identifieri983917 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesRubrivivax
    ProteomesiUP000007883: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei210 – 2101N6-carboxylysineUniRule annotation

    Interactioni

    Subunit structurei

    Heterohexadecamer of 8 large chains and 8 small chains.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RuBisCO large chain family. Type I subfamily.UniRule annotation

    Phylogenomic databases

    KOiK01601.

    Family and domain databases

    Gene3Di3.20.20.110. 1 hit.
    3.30.70.150. 1 hit.
    HAMAPiMF_01338. RuBisCO_L_type1.
    InterProiIPR020878. RuBisCo_large_chain_AS.
    IPR020888. RuBisCO_lsu.
    IPR000685. RuBisCO_lsu_C.
    IPR017443. RuBisCO_lsu_fd_N.
    IPR017444. RuBisCO_lsu_N.
    [Graphical view]
    PfamiPF00016. RuBisCO_large. 1 hit.
    PF02788. RuBisCO_large_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF51649. SSF51649. 1 hit.
    SSF54966. SSF54966. 1 hit.
    PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I0HVA8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKPHEPGAT GDQILDKKQR YSAGVLKYRQ MGYWDSDYVP KATDVVCLFR    50
    ITPQEGVDPI EAAAAVAGES STATWTVVWT DRLTACDSYR AKAYKVEPVP 100
    GRPGEYFAWV AYDLILFEEG SIANMTASLI GNVFSFKPLK AARLEDIQIP 150
    VAYVKTFKGP PTGLIVERER LDKFGRPLLG ATTKPKLGLS GRNYGRVIYE 200
    GLKGGLDFMK DDENINSQPF MHWRDRFLYV MDGVNKASAA TGEVKGSYLN 250
    VTGATMEDIY ERAEFAKELG SVVIMVDLII GWSAIQSIAN WARKNDMIVH 300
    MHRAGHGTYT RQKNHGVSFR VMAKWLRLAG VDHLHTGTAV GKLEGDPLTV 350
    QGYYNVCRDA YTKQDLPRGL FFDQDWADLR KVMPVASGGI HAGQMHQLID 400
    LFGDDVILQF GGGTIGHPAG IQAGAVANRV ALEAMVKARN EGRDIKNEGP 450
    EILQKAAQFC TPLKQALDTW KDVSFNYAST DQSDYAVTPA TSA 493
    Length:493
    Mass (Da):54,372
    Last modified:June 13, 2012 - v1
    Checksum:i780F4633E7415C06
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012320 Genomic DNA. Translation: BAL96945.1.
    RefSeqiWP_014429802.1. NC_017075.1.
    YP_005438444.1. NC_017075.1.

    Genome annotation databases

    EnsemblBacteriaiBAL96945; BAL96945; RGE_36060.
    GeneIDi12027736.
    KEGGirge:RGE_36060.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012320 Genomic DNA. Translation: BAL96945.1 .
    RefSeqi WP_014429802.1. NC_017075.1.
    YP_005438444.1. NC_017075.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAL96945 ; BAL96945 ; RGE_36060 .
    GeneIDi 12027736.
    KEGGi rge:RGE_36060.

    Phylogenomic databases

    KOi K01601.

    Enzyme and pathway databases

    BioCyci RGEL983917:GLJR-3646-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.110. 1 hit.
    3.30.70.150. 1 hit.
    HAMAPi MF_01338. RuBisCO_L_type1.
    InterProi IPR020878. RuBisCo_large_chain_AS.
    IPR020888. RuBisCO_lsu.
    IPR000685. RuBisCO_lsu_C.
    IPR017443. RuBisCO_lsu_fd_N.
    IPR017444. RuBisCO_lsu_N.
    [Graphical view ]
    Pfami PF00016. RuBisCO_large. 1 hit.
    PF02788. RuBisCO_large_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51649. SSF51649. 1 hit.
    SSF54966. SSF54966. 1 hit.
    PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of phototrophic betaproteobacterium Rubrivivax gelatinosus IL144."
      Nagashima S., Sekine M., Takami A., Shimizu T., Nakamura S., Aono E., Sakamoto K., Nakazawa H., Yamazaki S., Fujita N., Shimada K., Hanada S., Nagashima K.
      Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NBRC 100245 / IL144Imported.

    Entry informationi

    Entry nameiI0HVA8_RUBGI
    AccessioniPrimary (citable) accession number: I0HVA8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 13, 2012
    Last sequence update: June 13, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Miscellaneous

    The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel".UniRule annotation

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3