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I0HVA8

- I0HVA8_RUBGI

UniProt

I0HVA8 - I0HVA8_RUBGI

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Protein
Ribulose bisphosphate carboxylase large chain
Gene
cbbL, RGE_36060
Organism
Rubrivivax gelatinosus (strain NBRC 100245 / IL144)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site By similarity.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei132 – 1321Substrate; in homodimeric partner By similarityUniRule annotation
Binding sitei182 – 1821Substrate By similarityUniRule annotation
Active sitei184 – 1841Proton acceptor By similarityUniRule annotation
Binding sitei186 – 1861Substrate By similarityUniRule annotation
Metal bindingi210 – 2101Magnesium; via carbamate group By similarityUniRule annotation
Metal bindingi212 – 2121Magnesium By similarityUniRule annotation
Metal bindingi213 – 2131Magnesium By similarityUniRule annotation
Active sitei302 – 3021Proton acceptor By similarityUniRule annotation
Binding sitei303 – 3031Substrate By similarityUniRule annotation
Binding sitei335 – 3351Substrate By similarityUniRule annotation
Sitei342 – 3421Transition state stabilizer By similarityUniRule annotation
Binding sitei387 – 3871Substrate By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. monooxygenase activity Source: UniProtKB-KW
  3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. reductive pentose-phosphate cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported, MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Biological processi

Calvin cycleUniRule annotation, Carbon dioxide fixationUniRule annotation, PhotosynthesisUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciRGEL983917:GLJR-3646-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylase large chainUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCO large subunitUniRule annotation
Gene namesi
Name:cbbLUniRule annotationImported
Ordered Locus Names:RGE_36060Imported
OrganismiRubrivivax gelatinosus (strain NBRC 100245 / IL144)Imported
Taxonomic identifieri983917 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesRubrivivax
ProteomesiUP000007883: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei210 – 2101N6-carboxylysine By similarityUniRule annotation

Interactioni

Subunit structurei

Heterohexadecamer of 8 large chains and 8 small chains By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01601.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPiMF_01338. RuBisCO_L_type1.
InterProiIPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I0HVA8-1 [UniParc]FASTAAdd to Basket

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MNKPHEPGAT GDQILDKKQR YSAGVLKYRQ MGYWDSDYVP KATDVVCLFR    50
ITPQEGVDPI EAAAAVAGES STATWTVVWT DRLTACDSYR AKAYKVEPVP 100
GRPGEYFAWV AYDLILFEEG SIANMTASLI GNVFSFKPLK AARLEDIQIP 150
VAYVKTFKGP PTGLIVERER LDKFGRPLLG ATTKPKLGLS GRNYGRVIYE 200
GLKGGLDFMK DDENINSQPF MHWRDRFLYV MDGVNKASAA TGEVKGSYLN 250
VTGATMEDIY ERAEFAKELG SVVIMVDLII GWSAIQSIAN WARKNDMIVH 300
MHRAGHGTYT RQKNHGVSFR VMAKWLRLAG VDHLHTGTAV GKLEGDPLTV 350
QGYYNVCRDA YTKQDLPRGL FFDQDWADLR KVMPVASGGI HAGQMHQLID 400
LFGDDVILQF GGGTIGHPAG IQAGAVANRV ALEAMVKARN EGRDIKNEGP 450
EILQKAAQFC TPLKQALDTW KDVSFNYAST DQSDYAVTPA TSA 493
Length:493
Mass (Da):54,372
Last modified:June 13, 2012 - v1
Checksum:i780F4633E7415C06
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012320 Genomic DNA. Translation: BAL96945.1.
RefSeqiWP_014429802.1. NC_017075.1.
YP_005438444.1. NC_017075.1.

Genome annotation databases

EnsemblBacteriaiBAL96945; BAL96945; RGE_36060.
GeneIDi12027736.
KEGGirge:RGE_36060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012320 Genomic DNA. Translation: BAL96945.1 .
RefSeqi WP_014429802.1. NC_017075.1.
YP_005438444.1. NC_017075.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAL96945 ; BAL96945 ; RGE_36060 .
GeneIDi 12027736.
KEGGi rge:RGE_36060.

Phylogenomic databases

KOi K01601.

Enzyme and pathway databases

BioCyci RGEL983917:GLJR-3646-MONOMER.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPi MF_01338. RuBisCO_L_type1.
InterProi IPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of phototrophic betaproteobacterium Rubrivivax gelatinosus IL144."
    Nagashima S., Sekine M., Takami A., Shimizu T., Nakamura S., Aono E., Sakamoto K., Nakazawa H., Yamazaki S., Fujita N., Shimada K., Hanada S., Nagashima K.
    Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NBRC 100245 / IL144.

Entry informationi

Entry nameiI0HVA8_RUBGI
AccessioniPrimary (citable) accession number: I0HVA8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: September 3, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel" By similarity.UniRule annotation

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi