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I0HA57 (I0HA57_ACTM4) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP-Rule MF_00259 RuleBase RU003981 SAAS SAAS006222

Catalytic activity

Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP-Rule MF_00259

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. RuleBase RU003981 SAAS SAAS006222

Subunit structure

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP-Rule MF_00259 RuleBase RU003981 SAAS SAAS006222

Sequence similarities

Belongs to the GcvT family. HAMAP-Rule MF_00259 RuleBase RU003980

Sequences

Sequence LengthMass (Da)Tools
I0HA57 [UniParc].

Last modified June 13, 2012. Version 1.
Checksum: 4C55ADA552FFCBE2

FASTA39341,451
        10         20         30         40         50         60 
MTERGRPQPV TTLEPPVRRT ALFDVHTRLG AHLTTFAGWT MPLRYGSDIA EHHTVRTAAG 

        70         80         90        100        110        120 
LFDLSHMGRI EVTGRNAAEF LDYALAGRLS TVKVGRAKYT MLCHTTGGVL DDLVVYRLAA 

       130        140        150        160        170        180 
DRFLVVANAA NAPMVRAMLG EHANGFAVRI TDAGGSLIAV QGPASAEVIA TQGPASAEVI 

       190        200        210        220        230        240 
ATQGPASAKA MAIESLDLPY YGITEARVAG CDVLLARTGY TGEDGFEIYC SDADAATIWE 

       250        260        270        280        290        300 
SLRESGATPA GLACRDTLRL EAGMPLYGHE LTVRTTPFHA GLGRIVALDK ADFVGAESLR 

       310        320        330        340        350        360 
RVAAQGPSTV LTGLVTAGRR APRSGHAVLD PVSGERIGEV TSGAPSPTLG HPIAMAYVPP 

       370        380        390 
VFAAPGTRLV VDVRGTREDA EVVALPFYRR SPQ

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References

[1]"Complete genome sequence of Actinoplanes missouriensis 431 (= NBRC 102363)."
Ohnishi Y., Ishikawa J., Sekine M., Hosoyama A., Harada T., Narita H., Hata T., Konno Y., Tutikane K., Fujita N., Horinouchi S., Hayakawa M.
Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP012319 Genomic DNA. Translation: BAL89894.1.
RefSeqYP_005464410.1. NC_017093.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAL89894; BAL89894; AMIS_46740.
GeneID12051841.
KEGGams:AMIS_46740.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00605.

Family and domain databases

Gene3D3.30.1360.120. 2 hits.
HAMAPMF_00259. GcvT.
InterProIPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR006223. GcvT.
IPR022903. NH2_Me_Trfase.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PfamPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFPIRSF006487. GcvT. 1 hit.
TIGRFAMsTIGR00528. gcvT. 1 hit.
ProtoNetSearch...

Entry information

Entry nameI0HA57_ACTM4
AccessionPrimary (citable) accession number: I0HA57
Entry history
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: May 1, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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