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I0HA47

- I0HA47_ACTM4

UniProt

I0HA47 - I0HA47_ACTM4

Protein

Glutamate decarboxylase

Gene

AMIS_46640

Organism
Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 13 (01 Oct 2014)
      Sequence version 1 (13 Jun 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciAMIS512565:GL7J-4713-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Ordered Locus Names:AMIS_46640Imported
    OrganismiActinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431)Imported
    Taxonomic identifieri512565 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeActinoplanes
    ProteomesiUP000007882: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    KOiK01580.
    OMAiAQYYTFL.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    I0HA47-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKGSMLKHPR SERPAPEVLA TADVTIPRHE LPAGEMTPDD AYQIVHDELM    50
    LDGNARLNAA TFVTTWMEPQ ADRLMAECFD KNMIDKDEYP QTAEIEARCV 100
    NILSRLWHAP DARQATGCST TGSSEAAMLG GLALKRRWQR QGRTGRPNLV 150
    MGINVQVCWE KFANYWDVEM RLVPMDGDRY HLSAEEAVAL CDENTIGVVA 200
    ILGSTFDGSY EPVAEICAAL DAFQERTGID VPVHVDAASG GFVAPFLDRD 250
    LVWDFQLPRV SSINVSGHKY GLVYPGVGWI VWRDAQALPE DLIFWVNYLG 300
    DDMPTFALNF SRPGAQVVAQ YYNFLRLGFA GYARVQGYAR DVATRLAGMI 350
    ADLGPFELLT RGDELPVFAF KLRDEVTGYS VFDVSEALRE RGWQVPAYTF 400
    PKNREDLAAL RIVVRRGFTH DLADLLLEDL RRHVQRLEKQ AVPARDATTA 450
    TGFHH 455
    Length:455
    Mass (Da):50,910
    Last modified:June 13, 2012 - v1
    Checksum:iD351A56907B0AF43
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012319 Genomic DNA. Translation: BAL89884.1.
    RefSeqiWP_014444773.1. NC_017093.1.
    YP_005464400.1. NC_017093.1.

    Genome annotation databases

    EnsemblBacteriaiBAL89884; BAL89884; AMIS_46640.
    GeneIDi12051831.
    KEGGiams:AMIS_46640.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012319 Genomic DNA. Translation: BAL89884.1 .
    RefSeqi WP_014444773.1. NC_017093.1.
    YP_005464400.1. NC_017093.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAL89884 ; BAL89884 ; AMIS_46640 .
    GeneIDi 12051831.
    KEGGi ams:AMIS_46640.

    Phylogenomic databases

    KOi K01580.
    OMAi AQYYTFL.

    Enzyme and pathway databases

    BioCyci AMIS512565:GL7J-4713-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Actinoplanes missouriensis 431 (= NBRC 102363)."
      Ohnishi Y., Ishikawa J., Sekine M., Hosoyama A., Harada T., Narita H., Hata T., Konno Y., Tutikane K., Fujita N., Horinouchi S., Hayakawa M.
      Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431Imported.

    Entry informationi

    Entry nameiI0HA47_ACTM4
    AccessioniPrimary (citable) accession number: I0HA47
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 13, 2012
    Last sequence update: June 13, 2012
    Last modified: October 1, 2014
    This is version 13 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3