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Protein

Glutamate decarboxylase

Gene

AMIS_46640

Organism
Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:AMIS_46640Imported
OrganismiActinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431)Imported
Taxonomic identifieri512565 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicromonosporalesMicromonosporaceaeActinoplanes
Proteomesi
  • UP000007882 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei269N6-(pyridoxal phosphate)lysineUniRule annotation1

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili420 – 440Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KOiK01580
OMAiRPNLVMG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

I0HA47-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGSMLKHPR SERPAPEVLA TADVTIPRHE LPAGEMTPDD AYQIVHDELM
60 70 80 90 100
LDGNARLNAA TFVTTWMEPQ ADRLMAECFD KNMIDKDEYP QTAEIEARCV
110 120 130 140 150
NILSRLWHAP DARQATGCST TGSSEAAMLG GLALKRRWQR QGRTGRPNLV
160 170 180 190 200
MGINVQVCWE KFANYWDVEM RLVPMDGDRY HLSAEEAVAL CDENTIGVVA
210 220 230 240 250
ILGSTFDGSY EPVAEICAAL DAFQERTGID VPVHVDAASG GFVAPFLDRD
260 270 280 290 300
LVWDFQLPRV SSINVSGHKY GLVYPGVGWI VWRDAQALPE DLIFWVNYLG
310 320 330 340 350
DDMPTFALNF SRPGAQVVAQ YYNFLRLGFA GYARVQGYAR DVATRLAGMI
360 370 380 390 400
ADLGPFELLT RGDELPVFAF KLRDEVTGYS VFDVSEALRE RGWQVPAYTF
410 420 430 440 450
PKNREDLAAL RIVVRRGFTH DLADLLLEDL RRHVQRLEKQ AVPARDATTA

TGFHH
Length:455
Mass (Da):50,910
Last modified:June 13, 2012 - v1
Checksum:iD351A56907B0AF43
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012319 Genomic DNA Translation: BAL89884.1

Genome annotation databases

EnsemblBacteriaiBAL89884; BAL89884; AMIS_46640
KEGGiams:AMIS_46640
PATRICifig|512565.3.peg.4650

Similar proteinsi

Entry informationi

Entry nameiI0HA47_ACTM4
AccessioniPrimary (citable) accession number: I0HA47
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: April 25, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health