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I0GYX9

- I0GYX9_ACTM4

UniProt

I0GYX9 - I0GYX9_ACTM4

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei140 – 1401UniRule annotation
Active sitei577 – 5771UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciAMIS512565:GL7J-766-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:AMIS_7460Imported
OrganismiActinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431)Imported
Taxonomic identifieri512565 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeActinoplanes
ProteomesiUP000007882: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiWYGAGSA.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I0GYX9-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MTEPPAHLDR EGSDAALRAD IRRIGTLLGQ TLARQEGRPL LDLVEEIRAL
60 70 80 90 100
VRQDAPAAAD RLSAMDITTG TKLARAFSTY FHLANITEQV HRARDLQRRR
110 120 130 140 150
ARDGGWLDQA AARISEKGVP AEEIAAAARR LAVRPVFTAH PTEAARRSIL
160 170 180 190 200
SKLRQVADSL DAESAAAALY GATDTTVSTK RFAELIDLLW QTDELRLDRP
210 220 230 240 250
DPTDEARNAV YYLKDLYAEA APQVLDDLAE TLRRLGVETA PTSRPLTFGT
260 270 280 290 300
WIGGDRDGNP FVTPKVTRDV LLIQHEHGIQ ATEKAMDKLI DELSVSRRLR
310 320 330 340 350
GVSLDLSASL AQDLDNLPEI AARFRRVNAE EPYRLKVRAV KAKLANTRAR
360 370 380 390 400
LTNNTPHVPG RDYLGSDELI SDLELMRASL ARNSGQLPAI GIVATAIRQA
410 420 430 440 450
SAFGLQLATL DVREHAEKHH EVLQQMYTQV GEIDDYATLD RSDRTKLLAT
460 470 480 490 500
ELTGRRPLSS ADTPLTDSAR KTFDVFNTIR EAQDSFGPDV IETYIISMTL
510 520 530 540 550
GVDDVLAAAV LAREAGLVDI HTGRARVNIV PLLETPAELD AGGDLLDEML
560 570 580 590 600
SLPAYREIVR ARGDVQEVML GYSDSNKEAG ITTSQWRIHK AQRSLRDVAA
610 620 630 640 650
RHGVRLRLFH GRGGTVGRGG GPTHEAILAQ PYGTLDGAIK VTEQGEVISD
660 670 680 690 700
KYTVPALARE NLELTVAAVL QATLLHTTLQ VDPVRLKVWD SVMDTASDAA
710 720 730 740 750
FTQYRSLVEN PDLAAYFWAA TPTELLGALN IGSRPAKRPN ADAGLSGLRA
760 770 780 790 800
IPWVFGWTQT RQIVPGWFGV GTGLAAVRAA GLGNELDAMH ENWQFFRTFL
810 820 830 840 850
SNVEMMLAKT DLSIARRYVE TLVPEELHPI FHKIEREYEL TVQEVLAITG
860 870 880 890 900
GTELLSSQPE LSRTLGVRDT YLEPLHHLQV ALLRQYRDLD DAGRQIPTAP
910 920 930
GARRGPSDST ALERALLTTV NGIAAGMRNT G
Length:931
Mass (Da):102,221
Last modified:June 13, 2012 - v1
Checksum:i5ABF608B87ADD101
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012319 Genomic DNA. Translation: BAL85966.1.
RefSeqiYP_005460482.1. NC_017093.1.

Genome annotation databases

EnsemblBacteriaiBAL85966; BAL85966; AMIS_7460.
GeneIDi12049673.
KEGGiams:AMIS_7460.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012319 Genomic DNA. Translation: BAL85966.1 .
RefSeqi YP_005460482.1. NC_017093.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAL85966 ; BAL85966 ; AMIS_7460 .
GeneIDi 12049673.
KEGGi ams:AMIS_7460.

Phylogenomic databases

KOi K01595.
OMAi WYGAGSA.

Enzyme and pathway databases

BioCyci AMIS512565:GL7J-766-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Actinoplanes missouriensis 431 (= NBRC 102363)."
    Ohnishi Y., Ishikawa J., Sekine M., Hosoyama A., Harada T., Narita H., Hata T., Konno Y., Tutikane K., Fujita N., Horinouchi S., Hayakawa M.
    Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431Imported.

Entry informationi

Entry nameiI0GYX9_ACTM4
AccessioniPrimary (citable) accession number: I0GYX9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: October 1, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3