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I0F597

- I0F597_9BACI

UniProt

I0F597 - I0F597_9BACI

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Protein
2-oxoglutarate dehydrogenase E1 component
Gene
odhA, MY9_2119
Organism
Bacillus sp. JS
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.UniRule annotationSAAS annotations

Catalytic activityi

2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2.UniRule annotationSAAS annotations

Cofactori

Thiamine pyrophosphate By similarity.UniRule annotationSAAS annotations

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotations

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotations

Keywords - Ligandi

Thiamine pyrophosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciBSP1127744:GL8I-2203-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
2-oxoglutarate dehydrogenase E1 componentUniRule annotation (EC:1.2.4.2UniRule annotation)
Alternative name(s):
Alpha-ketoglutarate dehydrogenase
Gene namesi
Name:odhAUniRule annotation
ORF Names:MY9_2119Imported
OrganismiBacillus sp. JSImported
Taxonomic identifieri1127744 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000005213: Chromosome

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotationSAAS annotations

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00164.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
HAMAPiMF_01169. SucA_OdhA.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR023784. 2oxoglutarate_DH_E1_bac.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

I0F597-1 [UniParc]FASTAAdd to Basket

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MFQNSMKQRM NWEDFYGPNL GYALELYDQY TQDPDSIDPD LKEMFDELGA    50
PPSELKEASG TKEKGRVTAD LIQKIASAVR LAEDIRTYGH LNASVNPLRK 100
DGKKSELFPL SDYGLTEEEI KAIPASVICK DAPKNITNGL EAIQYLRNTY 150
KRTISFEFDH VHDFKEREWL TKMIESGELF QKNSDEKLSA VLERLTEVEG 200
FEQFLHRTFV GQKRFSIEGL DALVPVLDDI IAQSVKSGTT SVNIGMAHRG 250
RLNVLAHVLG KPYEIIFSEF QHAPNKDLVP SEGSIGISYG WTGDVKYHLG 300
ANRELQDAET KSARITLANN PSHLEFINPI VEGSTRAAQE TRTQSGYPVQ 350
DETKSLAILI HGDAAFPGEG IVAETLNLSS LKGYQVGGAI HIIANNMIGF 400
TTESAESRST KYASDLAKGY EIPIVHVNAD DPEACLSAVK FAVEYRKTFN 450
KDFLIDLIGY RRYGHNEMDE PSTTQPMLYD AVRKHPTVKQ IFAEKLVKEG 500
VLTEEVVQNI EKSVTKRIED AYQKVPSKKE HIACEIELPE PVSNGFPDVD 550
TSIDFDVLRK LNGELINWPE SFNVFGKLKR ILERRAKAFD DDRKVEWSLA 600
ESLAFASILK DGTPIRLTGQ DSERGTFAQR NLVLHDSETG EEFVPLHHLS 650
DCSTSFAVHN SPLSEGSVLG FEYGYNVHSP ETLVLWEAQY GDFANAAQVY 700
FDQFISAGRA KWGQKSGLVM LLPHGYEGQG PEHSSGRIER FLQLAAENNW 750
TVANLTSAAQ YFHILRRQAK MLLREEIRPL VIMTPKSLLR NPNTVSEVQE 800
LSESRFQPVY EQSGLSHDYE KVTRLVLSSG KVSIDISDHF NKLEDGKEWL 850
HIARIEQLYP FPAKGVKELF AKLPNLKEIV WVQEEPQNMG AWSYISPYLI 900
EIAPEGVSVQ YIGRRRRSSP AEGDPTVHKK EQERIVSDSL TRKN 944
Length:944
Mass (Da):106,323
Last modified:June 13, 2012 - v1
Checksum:i033EB535FAACF7C3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003492 Genomic DNA. Translation: AFI28653.1.
RefSeqiWP_014664273.1. NC_017743.1.
YP_006231909.1. NC_017743.1.

Genome annotation databases

EnsemblBacteriaiAFI28653; AFI28653; MY9_2119.
GeneIDi12769800.
KEGGibjs:MY9_2119.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003492 Genomic DNA. Translation: AFI28653.1 .
RefSeqi WP_014664273.1. NC_017743.1.
YP_006231909.1. NC_017743.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFI28653 ; AFI28653 ; MY9_2119 .
GeneIDi 12769800.
KEGGi bjs:MY9_2119.

Phylogenomic databases

KOi K00164.

Enzyme and pathway databases

BioCyci BSP1127744:GL8I-2203-MONOMER.

Family and domain databases

Gene3Di 3.40.50.970. 2 hits.
HAMAPi MF_01169. SucA_OdhA.
InterProi IPR011603. 2oxoglutarate_DH_E1.
IPR023784. 2oxoglutarate_DH_E1_bac.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
Pfami PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view ]
PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTi SM00861. Transket_pyr. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 2 hits.
TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome Sequence of the Plant Growth-Promoting Rhizobacterium Bacillus sp. Strain JS."
    Song J.Y., Kim H.A., Kim J.S., Kim S.Y., Jeong H., Kang S.G., Kim B.K., Kwon S.K., Lee C.H., Yu D.S., Kim B.S., Kim S.H., Kwon S.Y., Kim J.F.
    J. Bacteriol. 194:3760-3761(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JSImported.

Entry informationi

Entry nameiI0F597_9BACI
AccessioniPrimary (citable) accession number: I0F597
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: September 3, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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