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I0EE07 (I0EE07_HELPX) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length377 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS001608

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. RuleBase RU004188 HAMAP-Rule MF_01201

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site371Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2711Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1351Substrate By similarity HAMAP-Rule MF_01201
Binding site3191Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue371N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
I0EE07 [UniParc].

Last modified June 13, 2012. Version 1.
Checksum: 8447D4898F95B32B

FASTA37741,961
        10         20         30         40         50         60 
MLKRASFVEV NTASLRHNFS AAKSIVPKDA HIMAVVKANA YGVGAIKASE IFLQEGAHYL 

        70         80         90        100        110        120 
GVATLDEALE LRSYFSKTPI LILGYSPNSN ASMLIDNDLS TMIFSLEQAE VFSQMALKSQ 

       130        140        150        160        170        180 
KRLKIHLKID TGMHRLGLEP NFKSIETIKK IRALKGLEIE GIFTHLSNAD SNIKTHAKNQ 

       190        200        210        220        230        240 
MKAFNAFLEQ LSNQKIEFQY RHAYNSAGIL SLCNGNENRL LNLYRPGIML YGFYPSNEMK 

       250        260        270        280        290        300 
KSCPTILKNV ISLKAQIVQI RSVKKGEFIG YGEHFYTNEE TLVGVLALGY ADGLMRALGN 

       310        320        330        340        350        360 
RIQVAINNQL APLIGKVCMD QCFVKLNNIQ AKEGDEVILF GDKSAKANDA SEIATLLNTI 

       370 
PYETISTLSK RLERVYI 

« Hide

References

[1]Kersulyte D., Cabrera L., Pacheco R., Herrera P., Rodriguez C., Gilman R.H., Berg D.E.
Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Shi112 EMBL AFI01176.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003474 Genomic DNA. Translation: AFI01176.1.
RefSeqYP_006227669.1. NC_017741.1.

3D structure databases

ProteinModelPortalI0EE07.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFI01176; AFI01176; HPSH112_04885.
GeneID12772125.
KEGGhhp:HPSH112_04885.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycHPYL1163740:GLEO-948-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameI0EE07_HELPX
AccessionPrimary (citable) accession number: I0EE07
Entry history
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: July 9, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)