Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

I0E534 (I0E534_HELPX) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length377 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. RuleBase RU004188 HAMAP-Rule MF_01201

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site371Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2711Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1351Substrate By similarity HAMAP-Rule MF_01201
Binding site3191Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue371N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
I0E534 [UniParc].

Last modified June 13, 2012. Version 1.
Checksum: 0F2EEBA279A5AFC1

FASTA37741,893
        10         20         30         40         50         60 
MLKRASFVEV NTASLRHNFS AVKSIVPKDA HIMAVVKANA YGVGAIKASE IFLQEGANYL 

        70         80         90        100        110        120 
GVATLDEALE LRSYFSKTPI LILGYSPNSN ASMLIDNDLS AMIFSLEQAE VFSQTALKSQ 

       130        140        150        160        170        180 
KRLKVHLKID TGMHRLGLEP NFKSIEIIKK IRALKGLEME GIFTHLSNAD AKIKTHAKNQ 

       190        200        210        220        230        240 
MKAFNAFLEQ LLNQKIEFQY RHAYNSAGIL SLCNGNENRF LNLYRPGIML YGFYPSNGMK 

       250        260        270        280        290        300 
ETCPTILKNV ISLKAQIVQI RSVKKGEFIG YGEHFYTNEE TLVGVLALGY ADGLMRALGN 

       310        320        330        340        350        360 
RIQVAINNQL APLIGKVCMD QCFVKLNNIQ AKEGDEVILF GDKSAKANDA SEIAALLNTI 

       370 
PYETISTLSK RLERVYI 

« Hide

References

[1]Kersulyte D., Cabrera L., Pacheco R., Herrera P., Rodriguez C., Gilman R.H., Berg D.E.
Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Shi417 EMBL AFH98052.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003472 Genomic DNA. Translation: AFH98052.1.
RefSeqYP_006224546.1. NC_017739.1.

3D structure databases

ProteinModelPortalI0E534.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFH98052; AFH98052; HPSH417_04585.
GeneID12775303.
KEGGhhr:HPSH417_04585.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycHPYL1163739:GLEQ-898-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameI0E534_HELPX
AccessionPrimary (citable) accession number: I0E534
Entry history
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: February 19, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)