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H9ZZY7 (H9ZZY7_FERFK) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
DNA ligase RuleBase RU000617 HAMAP-Rule MF_00407

EC=6.5.1.1 RuleBase RU000617 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
Ordered Locus Names:FFONT_0304 EMBL AFH42294.1
OrganismFervidicoccus fontis (strain DSM 19380 / VKM B-2539 / Kam940) [Complete proteome] [HAMAP] EMBL AFH42294.1
Taxonomic identifier1163730 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiFervidicoccalesFervidicoccaceaeFervidicoccus

Protein attributes

Sequence length599 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617 HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2621N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2601ATP By similarity HAMAP-Rule MF_00407
Binding site2671ATP By similarity HAMAP-Rule MF_00407
Binding site2821ATP By similarity HAMAP-Rule MF_00407
Binding site3121ATP By similarity HAMAP-Rule MF_00407
Binding site3521ATP By similarity HAMAP-Rule MF_00407
Binding site4291ATP By similarity HAMAP-Rule MF_00407
Binding site4351ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
H9ZZY7 [UniParc].

Last modified June 13, 2012. Version 1.
Checksum: 573DF58B5B061B2C

FASTA59967,836
        10         20         30         40         50         60 
MDFEIIARTF DALEKISSRI ALTNALVDLF KQTSKDEVKI VVYLIQGRLW PDWKGMPEIG 

        70         80         90        100        110        120 
VAEKLLIKAA SIALNVKEEQ INKIYKEVGD LGKAIEQIKA SKDATAGTLT SFLGVQKKEK 

       130        140        150        160        170        180 
LSVKKIYESF VKIATAEGEG SRDIKLRVLA GLLKDAQPIE ARFIVRFVEG RLRINIGDAT 

       190        200        210        220        230        240 
VMDALSIAFT GTDANRPIIE RAYNLRADLG DIAEILVKDG INALQNITPK VGIPIRPMLA 

       250        260        270        280        290        300 
ERHNDPKVML EKVGGKAYVE YKYDGERAQI HKSNDEITIF SRRLENITHQ YPDVVEYSRK 

       310        320        330        340        350        360 
YIKANEAIVE GEIVAIDPDT RELRPFQILM TRKRKHDITK MMKEVPVSVF LFDAIYVDGK 

       370        380        390        400        410        420 
DLTNFPLPER RKYLESVIAQ SDDMQIAQYK YIDNAEDLEK MFYEAISNGA EGVMIKSISE 

       430        440        450        460        470        480 
KSIYQAGNRG WLWIKYKRDY RSEMSDSVDL VVVGAFYGKG KRAGKLSTIL VAGYDPDADV 

       490        500        510        520        530        540 
FRTVCKVGTG FTDEELDKMT EEFKGYIIDH KDPRVISEIT PDVWLIPKKV VEVIGAELTL 

       550        560        570        580        590 
SPLHTCAKGE ISKEAGLSIR FPRFINWRPD KGPEDATTCK ELVEMYRMQL KQVEEEQNP 

« Hide

References

[1]"Fervidicoccus fontis complete genome analysis confirms its distinct phylogenetic position and predicts its environmental function."
Lebedinsky A.V., Mardanov A.V., Gumerov V.M., Beletsky A.V., Kublanov I.V., Perevalova A.A., Bonch-Osmolovskaya E.A., Ravin N.V., Skryabin K.G.
Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 19380 / VKM B-2539 / Kam940.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003423 Genomic DNA. Translation: AFH42294.1.
RefSeqYP_005841746.1. NC_017461.1.

3D structure databases

ProteinModelPortalH9ZZY7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFH42294; AFH42294; FFONT_0304.
GeneID12449374.
KEGGffo:FFONT_0304.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK10747.

Enzyme and pathway databases

BioCycFFON1163730:GLD9-313-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH9ZZY7_FERFK
AccessionPrimary (citable) accession number: H9ZZY7
Entry history
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: February 19, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)