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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Thermus thermophilus JL-18
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei145 – 1451UniRule annotation
Active sitei531 – 5311UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciTTHE798128:GLMF-1444-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:TtJL18_1445Imported
OrganismiThermus thermophilus JL-18Imported
Taxonomic identifieri798128 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000007388 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H9ZSL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQDPFALLK AEVDLLGRLL GEAIWTLSGE RFFALVEEVR ALAKARRQGD
60 70 80 90 100
EAAGEALLAR VEGLSTEEAE ALVRAFTHYF HLVNLAEERH RVRVNRLRAQ
110 120 130 140 150
AETLESPRPE GFLALAKALK ERGLSLEEAE AHLNRLELLL TFTAHPTETR
160 170 180 190 200
RRTLRHHLEA LQRELEAGER ERLAARVALL YGTEEVRKAR PTVEDEIKGG
210 220 230 240 250
LYYLPTTLWE AVPRVVAGLE AALERVYGRR PRLKSPVRFR SWIGGDRDGN
260 270 280 290 300
PFVTPEVTAF AGRYAREVAR RRFLEALEDL VRDLSLAETR IPVPREVRER
310 320 330 340 350
GEGVERFPGE PYRRYFAALY RALEREEATT EGLLAALKAA ERGLREVGLG
360 370 380 390 400
RVAEAFLDPL EARLSAFGLE LAPLDLREES GRLLEAAAEL LRVGGVHPDF
410 420 430 440 450
LALPQEERER LLTEELKTAR PLLPVGEAPK GEALRVALGA LRVWRDKGAH
460 470 480 490 500
VVSMTHHPAD LLAVFLLARE VGLYRPGRPL PFDVVPLFET LEDLKRAPEV
510 520 530 540 550
VRRLLKNPVF RAHAEGRGGV EVMIGYSDSN KDAGFLMANL ALYEAQEALS
560 570 580 590 600
RVGEEVGLPV YFFHGRGTST ARGGGPAGRA IASLPPRSVG RRIRLTEQGE
610 620 630 640 650
ALADRYSHPD LAVRHLEQML YHFALAALDP GQEPEARWRE ALAQAAEEST
660 670 680 690 700
RRYRALLQEE GFFDFFEAFT PIREIGELPI ASRPVYRRGR VRDIRDLRAI
710 720 730 740 750
PWVMAWTQVR VLLPGWYGLS ALEELPLDLL REMYRGWPFF ASTLEAAAMA
760 770 780 790 800
LAKADMGVAR LYLRLVPEPL RFFYRRLAEE HARTVALLEA IFQAPLLHNQ
810 820 830 840 850
RTLERQIRLR NPYVDPINIV QVELLRRYRA PGGKEDEALR RALLLSILGV

AAGLRNAG
Length:858
Mass (Da):96,702
Last modified:June 13, 2012 - v1
Checksum:iB7C91D8268E9B73C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003252 Genomic DNA. Translation: AFH39325.1.
RefSeqiWP_014629932.1. NC_017587.1.
YP_006059111.1. NC_017587.1.

Genome annotation databases

EnsemblBacteriaiAFH39325; AFH39325; TtJL18_1445.
KEGGittl:TtJL18_1445.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003252 Genomic DNA. Translation: AFH39325.1.
RefSeqiWP_014629932.1. NC_017587.1.
YP_006059111.1. NC_017587.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFH39325; AFH39325; TtJL18_1445.
KEGGittl:TtJL18_1445.

Phylogenomic databases

KOiK01595.

Enzyme and pathway databases

BioCyciTTHE798128:GLMF-1444-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JL-18Imported.

Entry informationi

Entry nameiH9ZSL5_THETH
AccessioniPrimary (citable) accession number: H9ZSL5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: June 24, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.