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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Thermus thermophilus JL-18
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei145UniRule annotation1
Active sitei531UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciTTHE798128:G1H4J-1464-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:TtJL18_1445Imported
OrganismiThermus thermophilus JL-18Imported
Taxonomic identifieri798128 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000007388 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili151 – 178Sequence analysisAdd BLAST28
Coiled coili639 – 659Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KOiK01595
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

H9ZSL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQDPFALLK AEVDLLGRLL GEAIWTLSGE RFFALVEEVR ALAKARRQGD
60 70 80 90 100
EAAGEALLAR VEGLSTEEAE ALVRAFTHYF HLVNLAEERH RVRVNRLRAQ
110 120 130 140 150
AETLESPRPE GFLALAKALK ERGLSLEEAE AHLNRLELLL TFTAHPTETR
160 170 180 190 200
RRTLRHHLEA LQRELEAGER ERLAARVALL YGTEEVRKAR PTVEDEIKGG
210 220 230 240 250
LYYLPTTLWE AVPRVVAGLE AALERVYGRR PRLKSPVRFR SWIGGDRDGN
260 270 280 290 300
PFVTPEVTAF AGRYAREVAR RRFLEALEDL VRDLSLAETR IPVPREVRER
310 320 330 340 350
GEGVERFPGE PYRRYFAALY RALEREEATT EGLLAALKAA ERGLREVGLG
360 370 380 390 400
RVAEAFLDPL EARLSAFGLE LAPLDLREES GRLLEAAAEL LRVGGVHPDF
410 420 430 440 450
LALPQEERER LLTEELKTAR PLLPVGEAPK GEALRVALGA LRVWRDKGAH
460 470 480 490 500
VVSMTHHPAD LLAVFLLARE VGLYRPGRPL PFDVVPLFET LEDLKRAPEV
510 520 530 540 550
VRRLLKNPVF RAHAEGRGGV EVMIGYSDSN KDAGFLMANL ALYEAQEALS
560 570 580 590 600
RVGEEVGLPV YFFHGRGTST ARGGGPAGRA IASLPPRSVG RRIRLTEQGE
610 620 630 640 650
ALADRYSHPD LAVRHLEQML YHFALAALDP GQEPEARWRE ALAQAAEEST
660 670 680 690 700
RRYRALLQEE GFFDFFEAFT PIREIGELPI ASRPVYRRGR VRDIRDLRAI
710 720 730 740 750
PWVMAWTQVR VLLPGWYGLS ALEELPLDLL REMYRGWPFF ASTLEAAAMA
760 770 780 790 800
LAKADMGVAR LYLRLVPEPL RFFYRRLAEE HARTVALLEA IFQAPLLHNQ
810 820 830 840 850
RTLERQIRLR NPYVDPINIV QVELLRRYRA PGGKEDEALR RALLLSILGV

AAGLRNAG
Length:858
Mass (Da):96,702
Last modified:June 13, 2012 - v1
Checksum:iB7C91D8268E9B73C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003252 Genomic DNA Translation: AFH39325.1
RefSeqiWP_014629932.1, NC_017587.1

Genome annotation databases

EnsemblBacteriaiAFH39325; AFH39325; TtJL18_1445
KEGGittl:TtJL18_1445
PATRICifig|798128.4.peg.1404

Similar proteinsi

Entry informationi

Entry nameiH9ZSL5_THETH
AccessioniPrimary (citable) accession number: H9ZSL5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: March 28, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health