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Protein
Submitted name:

Enhancer of zeste 2 polycomb repressive complex 2 subunit

Gene

EZH2

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Enhancer of zeste 2 polycomb repressive complex 2 subunitImported
Submitted name:
Histone-lysine N-methyltransferase EZH2 isoform cImported
Gene namesi
Name:EZH2Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 3

Subcellular locationi

GO - Cellular componenti

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini503 – 605CXCInterPro annotationAdd BLAST103
Domaini612 – 727SETInterPro annotationAdd BLAST116

Phylogenomic databases

eggNOGiKOG1079. Eukaryota.
COG2940. LUCA.
GeneTreeiENSGT00780000121845.
KOiK11430.

Family and domain databases

InterProiView protein in InterPro
IPR026489. CXC_dom.
IPR021654. EZH1/EZH2.
IPR001005. SANT/Myb.
IPR001214. SET_dom.
IPR033467. Tesmin/TSO1-like_CXC.
PfamiView protein in Pfam
PF11616. EZH2_WD-Binding. 1 hit.
PF00856. SET. 1 hit.
SMARTiView protein in SMART
SM01114. CXC. 1 hit.
SM00717. SANT. 2 hits.
SM00317. SET. 1 hit.
PROSITEiView protein in PROSITE
PS51633. CXC. 1 hit.
PS50280. SET. 1 hit.

Sequencei

Sequence statusi: Complete.

H9Z6A2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKS MFSSNRQKIL
60 70 80 90 100
ERTEILNQEW KQRRIQPVHI LTSVSSLRGT RECSVTSDLD FPTQVIPLKT
110 120 130 140 150
LNAVASVPIM YSWSPLQQNF MVEDETVLHN IPYMGDEVLD QDGTFIEELI
160 170 180 190 200
KNYDGKVHGD RECGFINDEI FVELVNALGQ YNDDDDDDDG DDPEEREEKQ
210 220 230 240 250
KDLEDHRDDK ESRPPRKFPS DKIFEAISSM FPDKGTAEEL KEKYKELTEQ
260 270 280 290 300
QLPGALPPEC TPNIDGPNAK SVQREQSLHS FHTLFCRRCF KYDCFLHPFH
310 320 330 340 350
ATPNTYKRKN TETALDNKPC GPQCYQHLEG AKEFAAALTA ERIKTPPKRP
360 370 380 390 400
GGRRRGRLPN NSSRPSTPTI NVLESKDTDS DREAGTETGG ENNDKEEEEK
410 420 430 440 450
KDETSSSSEA NSRCQTPIKM KPNIEPPENV EWSGAEASMF RVLIGTYYDN
460 470 480 490 500
FCAIARLIGT KTCRQVYEFR VKESSIIAPA PAEDVDTPPR KKKRKHRLWA
510 520 530 540 550
AHCRKIQLKK DGSSNHVYNY QPCDHPRQPC DSSCPCVIAQ NFCEKFCQCS
560 570 580 590 600
SECQNRFPGC RCKAQCNTKQ CPCYLAVREC DPDLCLTCGA ADHWDSKNVS
610 620 630 640 650
CKNCSIQRGS KKHLLLAPSD VAGWGIFIKD PVQKNEFISE YCGEIISQDE
660 670 680 690 700
ADRRGKVYDK YMCSFLFNLN NDFVVDATRK GNKIRFANHS VNPNCYAKVM
710 720 730 740
MVNGDHRIGI FAKRAIQTGE ELFFDYRYSQ ADALKYVGIE REMEIP
Length:746
Mass (Da):85,363
Last modified:June 13, 2012 - v1
Checksum:i1B5029EB9D509BE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03029815 Genomic DNA. No translation available.
JSUE03029816 Genomic DNA. No translation available.
JSUE03029817 Genomic DNA. No translation available.
JU474664 mRNA. Translation: AFH31468.1.
JV046437 mRNA. Translation: AFI36508.1.
JV636024 mRNA. Translation: AFJ71364.1.
RefSeqiNP_001253432.1. NM_001266503.1.
UniGeneiMmu.2779.

Genome annotation databases

EnsembliENSMMUT00000060314; ENSMMUP00000060546; ENSMMUG00000013494.
GeneIDi709075.
KEGGimcc:709075.

Similar proteinsi

Entry informationi

Entry nameiH9Z6A2_MACMU
AccessioniPrimary (citable) accession number: H9Z6A2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: August 30, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported