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H9Z6A2

- H9Z6A2_MACMU

UniProt

H9Z6A2 - H9Z6A2_MACMU

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Protein
Submitted name:

Histone-lysine N-methyltransferase EZH2 isoform c

Gene
EZH2
Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. chromatin binding Source: InterPro
  2. histone-lysine N-methyltransferase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Histone-lysine N-methyltransferase EZH2 isoform cImported
Gene namesi
Name:EZH2Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

PTM / Processingi

Proteomic databases

PRIDEiH9Z6A2.

Structurei

3D structure databases

ProteinModelPortaliH9Z6A2.
SMRiH9Z6A2. Positions 40-68, 520-729.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotations

Phylogenomic databases

KOiK11430.

Family and domain databases

InterProiIPR026489. CXC_dom.
IPR021654. EZH2_WD-Binding.
IPR001005. SANT/Myb.
IPR001214. SET_dom.
[Graphical view]
PfamiPF11616. EZH2_WD-Binding. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00717. SANT. 2 hits.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51633. CXC. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H9Z6A2-1 [UniParc]FASTAAdd to Basket

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MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKS MFSSNRQKIL    50
ERTEILNQEW KQRRIQPVHI LTSVSSLRGT RECSVTSDLD FPTQVIPLKT 100
LNAVASVPIM YSWSPLQQNF MVEDETVLHN IPYMGDEVLD QDGTFIEELI 150
KNYDGKVHGD RECGFINDEI FVELVNALGQ YNDDDDDDDG DDPEEREEKQ 200
KDLEDHRDDK ESRPPRKFPS DKIFEAISSM FPDKGTAEEL KEKYKELTEQ 250
QLPGALPPEC TPNIDGPNAK SVQREQSLHS FHTLFCRRCF KYDCFLHPFH 300
ATPNTYKRKN TETALDNKPC GPQCYQHLEG AKEFAAALTA ERIKTPPKRP 350
GGRRRGRLPN NSSRPSTPTI NVLESKDTDS DREAGTETGG ENNDKEEEEK 400
KDETSSSSEA NSRCQTPIKM KPNIEPPENV EWSGAEASMF RVLIGTYYDN 450
FCAIARLIGT KTCRQVYEFR VKESSIIAPA PAEDVDTPPR KKKRKHRLWA 500
AHCRKIQLKK DGSSNHVYNY QPCDHPRQPC DSSCPCVIAQ NFCEKFCQCS 550
SECQNRFPGC RCKAQCNTKQ CPCYLAVREC DPDLCLTCGA ADHWDSKNVS 600
CKNCSIQRGS KKHLLLAPSD VAGWGIFIKD PVQKNEFISE YCGEIISQDE 650
ADRRGKVYDK YMCSFLFNLN NDFVVDATRK GNKIRFANHS VNPNCYAKVM 700
MVNGDHRIGI FAKRAIQTGE ELFFDYRYSQ ADALKYVGIE REMEIP 746
Length:746
Mass (Da):85,363
Last modified:June 13, 2012 - v1
Checksum:i1B5029EB9D509BE5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JU474664 mRNA. Translation: AFH31468.1.
JV046437 mRNA. Translation: AFI36508.1.
JV636024 mRNA. Translation: AFJ71364.1.
RefSeqiNP_001253432.1. NM_001266503.1.
UniGeneiMmu.2779.

Genome annotation databases

GeneIDi709075.
KEGGimcc:709075.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JU474664 mRNA. Translation: AFH31468.1 .
JV046437 mRNA. Translation: AFI36508.1 .
JV636024 mRNA. Translation: AFJ71364.1 .
RefSeqi NP_001253432.1. NM_001266503.1.
UniGenei Mmu.2779.

3D structure databases

ProteinModelPortali H9Z6A2.
SMRi H9Z6A2. Positions 40-68, 520-729.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi H9Z6A2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 709075.
KEGGi mcc:709075.

Organism-specific databases

CTDi 2146.

Phylogenomic databases

KOi K11430.

Family and domain databases

InterProi IPR026489. CXC_dom.
IPR021654. EZH2_WD-Binding.
IPR001005. SANT/Myb.
IPR001214. SET_dom.
[Graphical view ]
Pfami PF11616. EZH2_WD-Binding. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00717. SANT. 2 hits.
SM00317. SET. 1 hit.
[Graphical view ]
PROSITEi PS51633. CXC. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "De novo assembly of the rhesus macaque transcriptome from NextGen mRNA sequences."
    Pandey S., Maudhoo M.D., Guda C., Ferguson B., Fox H., Norgren R.B.
    Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: OrbitalImported, TestisImported and ThymusImported.

Entry informationi

Entry nameiH9Z6A2_MACMU
AccessioniPrimary (citable) accession number: H9Z6A2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: April 16, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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