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H9Z6A2

- H9Z6A2_MACMU

UniProt

H9Z6A2 - H9Z6A2_MACMU

Protein
Submitted name:

Histone-lysine N-methyltransferase EZH2 isoform c

Gene

EZH2

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (13 Jun 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. chromatin binding Source: InterPro
    2. histone-lysine N-methyltransferase activity Source: InterPro

    Keywords - Molecular functioni

    MethyltransferaseImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Histone-lysine N-methyltransferase EZH2 isoform cImported
    Gene namesi
    Name:EZH2Imported
    OrganismiMacaca mulatta (Rhesus macaque)Imported
    Taxonomic identifieri9544 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

    PTM / Processingi

    Proteomic databases

    PRIDEiH9Z6A2.

    Structurei

    3D structure databases

    ProteinModelPortaliH9Z6A2.
    SMRiH9Z6A2. Positions 40-68, 520-729.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation
    Contains SET domain.SAAS annotation

    Phylogenomic databases

    KOiK11430.

    Family and domain databases

    InterProiIPR026489. CXC_dom.
    IPR021654. EZH2_WD-Binding.
    IPR001005. SANT/Myb.
    IPR001214. SET_dom.
    [Graphical view]
    PfamiPF11616. EZH2_WD-Binding. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view]
    SMARTiSM00717. SANT. 2 hits.
    SM00317. SET. 1 hit.
    [Graphical view]
    PROSITEiPS51633. CXC. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H9Z6A2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKS MFSSNRQKIL    50
    ERTEILNQEW KQRRIQPVHI LTSVSSLRGT RECSVTSDLD FPTQVIPLKT 100
    LNAVASVPIM YSWSPLQQNF MVEDETVLHN IPYMGDEVLD QDGTFIEELI 150
    KNYDGKVHGD RECGFINDEI FVELVNALGQ YNDDDDDDDG DDPEEREEKQ 200
    KDLEDHRDDK ESRPPRKFPS DKIFEAISSM FPDKGTAEEL KEKYKELTEQ 250
    QLPGALPPEC TPNIDGPNAK SVQREQSLHS FHTLFCRRCF KYDCFLHPFH 300
    ATPNTYKRKN TETALDNKPC GPQCYQHLEG AKEFAAALTA ERIKTPPKRP 350
    GGRRRGRLPN NSSRPSTPTI NVLESKDTDS DREAGTETGG ENNDKEEEEK 400
    KDETSSSSEA NSRCQTPIKM KPNIEPPENV EWSGAEASMF RVLIGTYYDN 450
    FCAIARLIGT KTCRQVYEFR VKESSIIAPA PAEDVDTPPR KKKRKHRLWA 500
    AHCRKIQLKK DGSSNHVYNY QPCDHPRQPC DSSCPCVIAQ NFCEKFCQCS 550
    SECQNRFPGC RCKAQCNTKQ CPCYLAVREC DPDLCLTCGA ADHWDSKNVS 600
    CKNCSIQRGS KKHLLLAPSD VAGWGIFIKD PVQKNEFISE YCGEIISQDE 650
    ADRRGKVYDK YMCSFLFNLN NDFVVDATRK GNKIRFANHS VNPNCYAKVM 700
    MVNGDHRIGI FAKRAIQTGE ELFFDYRYSQ ADALKYVGIE REMEIP 746
    Length:746
    Mass (Da):85,363
    Last modified:June 13, 2012 - v1
    Checksum:i1B5029EB9D509BE5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JU474664 mRNA. Translation: AFH31468.1.
    JV046437 mRNA. Translation: AFI36508.1.
    JV636024 mRNA. Translation: AFJ71364.1.
    RefSeqiNP_001253432.1. NM_001266503.1.
    UniGeneiMmu.2779.

    Genome annotation databases

    GeneIDi709075.
    KEGGimcc:709075.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JU474664 mRNA. Translation: AFH31468.1 .
    JV046437 mRNA. Translation: AFI36508.1 .
    JV636024 mRNA. Translation: AFJ71364.1 .
    RefSeqi NP_001253432.1. NM_001266503.1.
    UniGenei Mmu.2779.

    3D structure databases

    ProteinModelPortali H9Z6A2.
    SMRi H9Z6A2. Positions 40-68, 520-729.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi H9Z6A2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 709075.
    KEGGi mcc:709075.

    Organism-specific databases

    CTDi 2146.

    Phylogenomic databases

    KOi K11430.

    Family and domain databases

    InterProi IPR026489. CXC_dom.
    IPR021654. EZH2_WD-Binding.
    IPR001005. SANT/Myb.
    IPR001214. SET_dom.
    [Graphical view ]
    Pfami PF11616. EZH2_WD-Binding. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view ]
    SMARTi SM00717. SANT. 2 hits.
    SM00317. SET. 1 hit.
    [Graphical view ]
    PROSITEi PS51633. CXC. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "De novo assembly of the rhesus macaque transcriptome from NextGen mRNA sequences."
      Pandey S., Maudhoo M.D., Guda C., Ferguson B., Fox H., Norgren R.B.
      Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: OrbitalImported, TestisImported and ThymusImported.

    Entry informationi

    Entry nameiH9Z6A2_MACMU
    AccessioniPrimary (citable) accession number: H9Z6A2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 13, 2012
    Last sequence update: June 13, 2012
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)