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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

Spiaf_1801

Organism
Spirochaeta africana (strain ATCC 700263 / DSM 8902 / Z-7692)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase
LigandPyruvateImported

Enzyme and pathway databases

BioCyciSAFR889378:G1H2N-1790-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:Spiaf_1801Imported
OrganismiSpirochaeta africana (strain ATCC 700263 / DSM 8902 / Z-7692)Imported
Taxonomic identifieri889378 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeSpirochaeta
Proteomesi
  • UP000007383 Componenti: Chromosome

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 77Lipoyl-bindingInterPro annotationAdd BLAST76
Domaini173 – 210Peripheral subunit-binding (PSBD)InterPro annotationAdd BLAST38

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotation

Phylogenomic databases

KOiK00627
OMAiTMEFESF
OrthoDBiPOG091H04EL

Family and domain databases

Gene3Di3.30.559.10, 1 hit
4.10.320.10, 1 hit
InterProiView protein in InterPro
IPR001078 2-oxoacid_DH_actylTfrase
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR036625 E3-bd_dom_sf
IPR004167 PSBD
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02817 E3_binding, 1 hit
SUPFAMiSSF47005 SSF47005, 1 hit
SSF51230 SSF51230, 1 hit
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 1 hit
PS51826 PSBD, 1 hit

Sequencei

Sequence statusi: Complete.

H9UK15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEPILMTAL SPTMEDGTIV AWSKNEGDEI SAGDVLCEVE TDKATMDYES
60 70 80 90 100
TQDGVLLKIL LGEGSSAKVG DPIGILGEAG EDVADLEKEL KAQAKSGGDS
110 120 130 140 150
SGSADSTEAA GSEAKDAPKA DASATDTGSA GGDAASSAGS DRGDAAAQRG
160 170 180 190 200
GARKAGGPTA GSSELPESDR SIKASPLARK LAASRNIDLR MIQGSGPGGR
210 220 230 240 250
IVKADIESAN PAHLTPQAPA GGGAAAAAGA PVMADREEPV AGKRKVIARR
260 270 280 290 300
LSESKFSAPH YYLKSTAEMD SLIAARSMLN RELPEKVGFN AFMIKFAAEA
310 320 330 340 350
LKRHPEVNAS WQEDSIRYFG SIDIGLAVDL GNGLITPIVR NCGAKGVTQI
360 370 380 390 400
DAELKELIEK ARSNSLQPDE YSGATFSISN LGSFGVDEFT AIINPPGAAI
410 420 430 440 450
LALGQTRKTP VVGENDQIRV ASTMTMSLSC DHRVIDGALA GRFIHELTRM

IESPVRVLF
Length:459
Mass (Da):47,582
Last modified:June 13, 2012 - v1
Checksum:i6F75ACF97077760A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003282 Genomic DNA Translation: AFG37858.1
RefSeqiWP_014455841.1, NC_017098.1

Genome annotation databases

EnsemblBacteriaiAFG37858; AFG37858; Spiaf_1801
KEGGisfc:Spiaf_1801
PATRICifig|889378.3.peg.1790

Similar proteinsi

Entry informationi

Entry nameiH9UK15_SPIAZ
AccessioniPrimary (citable) accession number: H9UK15
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: March 28, 2018
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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