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Protein
Submitted name:

G protein-coupled receptor 21

Gene

RABGAP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
G protein-coupled receptor 21Imported
Submitted name:
Rab GTPase-activating protein 1Imported
Gene namesi
Name:RABGAP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000011454.16.
HGNCiHGNC:17155. RABGAP1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei32 – 59HelicalSequence analysisAdd BLAST28
Transmembranei71 – 92HelicalSequence analysisAdd BLAST22
Transmembranei104 – 125HelicalSequence analysisAdd BLAST22
Transmembranei146 – 169HelicalSequence analysisAdd BLAST24
Transmembranei189 – 214HelicalSequence analysisAdd BLAST26
Transmembranei253 – 274HelicalSequence analysisAdd BLAST22
Transmembranei286 – 307HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000011454.

Expressioni

Gene expression databases

BgeeiENSG00000011454.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 304G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST260

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
KOiK04318.
OMAiCAPLLNH.
OrthoDBiEOG091G092Z.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

H9NIL4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSTLDGNQS SHPFCLLAFG YLETVNFCLL EVLIIVFLTV LIISGNIIVI
60 70 80 90 100
FVFHCAPLLN HHTTSYFIQT MAYADLFVGV SCVVPSLSLL HHPLPVEESL
110 120 130 140 150
TCQIFGFVVS VLKSVSMASL ACISIDRYIA ITKPLTYNTL VTPWRLRLCI
160 170 180 190 200
FLIWLYSTLV FLPSFFHWGK PGYHGDVFQW CAESWHTDSY FTLFIVMMLY
210 220 230 240 250
APAALIVCFT YFNIFRICQQ HTKDISERQA RFSSQSGETG EVQACPDKRY
260 270 280 290 300
AMVLFRITSV FYILWLPYII YFLLESSTGH SNRFASFLTT WLAISNSFCN
310 320 330 340
CVIYSLSNSV FQRGLKRLSG AMCTSCASQT TANDPYTVRS KGPLNGCHI
Length:349
Mass (Da):39,515
Last modified:June 13, 2012 - v1
Checksum:i5369DFC216E9EEC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007066 Genomic DNA. No translation available.
AL358946 Genomic DNA. No translation available.
AL365338 Genomic DNA. No translation available.
JQ308169 Genomic DNA. Translation: AFF59479.1.
RefSeqiNP_005285.1. NM_005294.2.
XP_005251990.1. XM_005251933.3.
UniGeneiHs.722039.

Genome annotation databases

EnsembliENST00000616002; ENSP00000482287; ENSG00000011454.
GeneIDi2844.
KEGGihsa:2844.

Similar proteinsi

Entry informationi

Entry nameiH9NIL4_HUMAN
AccessioniPrimary (citable) accession number: H9NIL4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: October 25, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported