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Protein
Submitted name:

Lys-63-specific deubiquitinase BRCC36

Gene

BRCC3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Lys-63-specific deubiquitinase BRCC36Imported
Gene namesi
Name:BRCC3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000185515.14.
HGNCiHGNC:24185. BRCC3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185515.

PTM / Processingi

Proteomic databases

PaxDbiH9KVA9.
PeptideAtlasiH9KVA9.
PRIDEiH9KVA9.

Expressioni

Gene expression databases

BgeeiENSG00000185515.
ExpressionAtlasiH9KVA9. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliH9KVA9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 178JAB_MPNInterPro annotationAdd BLAST168

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili285 – 317Sequence analysisAdd BLAST33

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1555. Eukaryota.
COG1310. LUCA.
GeneTreeiENSGT00390000000360.
OMAiXYERIEI.

Family and domain databases

CDDicd08068. MPN_BRCC36. 1 hit.
InterProiView protein in InterPro
IPR000555. JAMM/MPN+_dom.
IPR033860. MPN_BRCC36.
PfamiView protein in Pfam
PF01398. JAB. 1 hit.
SMARTiView protein in SMART
SM00232. JAB_MPN. 1 hit.

Sequencei

Sequence statusi: Complete.

H9KVA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVQVVQAVQ AVHLESDAFL VCLNHALSTE KEEVMGLCIG ELNDDTRSDS
60 70 80 90 100
KFAYTGTEMR TVAEKVDAVR IVHIHSVIIL RRSDKRKDRV EISPEQLSAA
110 120 130 140 150
STETHRLAEL TGRPMRVVGW YHSHPHITVW PSHVDVRTQA MYQMMDQGFV
160 170 180 190 200
GLIFSCFIED KNTKTGRVLY TCFQSIQAQK SSESLHGPRD FWSSSQHISI
210 220 230 240 250
EGQKEEERYE RIEIPIHIVP HVTIGKVCLE SAVELPKILC QEEQDAYRRI
260 270 280 290 300
HSLTHLDSVT KIHNGSEVFT KNLCSQMSAV SGPLLQWLED RLEQNQQHLQ
310
ELQQEKEELM QELSSLE
Length:317
Mass (Da):36,239
Last modified:October 29, 2014 - v2
Checksum:iC46012ED2A8DED9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX293995 Genomic DNA. No translation available.
BX470111 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000399042; ENSP00000381998; ENSG00000185515.
UCSCiuc065cjs.1. human.

Similar proteinsi

Entry informationi

Entry nameiH9KVA9_HUMAN
AccessioniPrimary (citable) accession number: H9KVA9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: October 29, 2014
Last modified: September 27, 2017
This is version 40 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported