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Protein
Submitted name:

Uncharacterized protein

Gene

PTGS2

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. heme binding Source: Ensembl
  2. peroxidase activity Source: InterPro
  3. prostaglandin-endoperoxide synthase activity Source: Ensembl

GO - Biological processi

  1. brown fat cell differentiation Source: Ensembl
  2. cellular response to hypoxia Source: Ensembl
  3. cyclooxygenase pathway Source: Ensembl
  4. inflammatory response Source: InterPro
  5. positive regulation of brown fat cell differentiation Source: Ensembl
  6. positive regulation of fever generation Source: Ensembl
  7. regulation of blood pressure Source: Ensembl
  8. regulation of cell proliferation Source: Ensembl
  9. response to oxidative stress Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:PTGS2Imported
OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
Taxonomic identifieri28377 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaIguanidaePolychrotinaeAnolis
ProteomesiUP000001646 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. neuron projection Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000010743.
InParanoidiH9G4Z6.
KOiK11987.
OrthoDBiEOG7RFTHC.
TreeFamiTF329675.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiIPR029576. COX-2.
IPR000742. EG-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view]
PANTHERiPTHR11903:SF8. PTHR11903:SF8. 1 hit.
PfamiPF03098. An_peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00457. ANPEROXIDASE.
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H9G4Z6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLPCAVLFA LLALSHAVNP CCSNPCHNRG VCMTTGFDTY ACDCTRTGYY
60 70 80 90 100
GENCTTPEFL TWLKLKLKPT PDMVHYILTH FKGVWNIINN IPFLHRAIMT
110 120 130 140 150
YILMSRSHLI ESPPTYNGHY SYKSWEAYSN LSYYTRSLPP VEHNCPTPMG
160 170 180 190 200
IKGKKELPDS QIIVEKFLMR RKFIPDPQGT NVMFTFFAQH FTHQFFKTDH
210 220 230 240 250
RKGPEFTKGL GHGVDLSHIY GETLDRQMKL RLLKDGKLKF QMIDGEMYPP
260 270 280 290 300
TVKDTQAEMI YPPHIPEHLR FCVGQEVFGL VPGLMMYATL WLREHNRVCD
310 320 330 340 350
VLKGEHPEWD DEQLFQTTRL ILIGETIKIV IEDYVQHLSG YHFKLKFDPE
360 370 380 390 400
LLFNQRFQYQ NRIAAEFNTL YHWHPLLPDT FNIQDQEYTY QQFVYNNSIM
410 420 430 440 450
LDHGLSHMVQ SFSKQIAGRV AGGRNVPVAV LKVAKASIDQ SRQMRYQSLN
460 470 480 490 500
EYRKHFLLKP FQSFEELTGE KEMAAELKEL YGDIDAMELY PALLVEKPRP
510 520 530 540 550
GAIFGETMIE LGAPFSLKGL MGNAICSPEY WKPSTFGGKV GFDIVNTASL
560 570 580 590 600
QRLVCNNVAG CPLTAFHVLT QETKATSNTS TTSASLDEIN PAVLLKERSA

EL
Length:602
Mass (Da):68,947
Last modified:June 26, 2013 - v2
Checksum:i46DC4E70ECA8E6FE
GO

Sequence databases

RefSeqiXP_003223472.1. XM_003223424.2.

Genome annotation databases

EnsembliENSACAT00000001287; ENSACAP00000001254; ENSACAG00000001178.
GeneIDi100560130.
KEGGiacs:100560130.

Cross-referencesi

Sequence databases

RefSeqiXP_003223472.1. XM_003223424.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSACAT00000001287; ENSACAP00000001254; ENSACAG00000001178.
GeneIDi100560130.
KEGGiacs:100560130.

Organism-specific databases

CTDi5743.

Phylogenomic databases

GeneTreeiENSGT00390000010743.
InParanoidiH9G4Z6.
KOiK11987.
OrthoDBiEOG7RFTHC.
TreeFamiTF329675.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiIPR029576. COX-2.
IPR000742. EG-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view]
PANTHERiPTHR11903:SF8. PTHR11903:SF8. 1 hit.
PfamiPF03098. An_peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00457. ANPEROXIDASE.
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The Genome Sequence of Anolis carolinensis (Green Anole Lizard)."
    The Genome Sequencing Platform
    Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J., Lander E.S., Lindblad-Toh K.
    Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH9G4Z6_ANOCA
AccessioniPrimary (citable) accession number: H9G4Z6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: June 26, 2013
Last modified: January 7, 2015
This is version 14 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.