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Protein
Submitted name:

CYLD lysine 63 deubiquitinase

Gene

CYLD

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseImported

Protein family/group databases

MEROPSiC67.001.

Names & Taxonomyi

Protein namesi
Submitted name:
CYLD lysine 63 deubiquitinaseImported
Submitted name:
Ubiquitin carboxyl-terminal hydrolase CYLD isoform 2Imported
Gene namesi
Name:CYLDImported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 20

Expressioni

Gene expression databases

ExpressionAtlasiH9EUD5. baseline.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini153 – 198CAP-GlyInterPro annotationAdd BLAST46
Domaini489 – 532CAP-GlyInterPro annotationAdd BLAST44
Domaini589 – 947USPInterPro annotationAdd BLAST359

Sequence similaritiesi

Belongs to the peptidase C19 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG3556. Eukaryota.
ENOG410XP6I. LUCA.
GeneTreeiENSGT00390000018123.

Family and domain databases

Gene3Di2.30.30.190. 3 hits.
InterProiView protein in InterPro
IPR036859. CAP-Gly_dom_sf.
IPR000938. CAP-Gly_domain.
IPR001394. Peptidase_C19_UCH.
IPR018200. USP_CS.
IPR028889. USP_dom.
PfamiView protein in Pfam
PF01302. CAP_GLY. 2 hits.
PF00443. UCH. 1 hit.
SMARTiView protein in SMART
SM01052. CAP_GLY. 3 hits.
SUPFAMiSSF74924. SSF74924. 3 hits.
PROSITEiView protein in PROSITE
PS00845. CAP_GLY_1. 1 hit.
PS50245. CAP_GLY_2. 2 hits.
PS00972. USP_1. 1 hit.
PS50235. USP_3. 1 hit.

Sequencei

Sequence statusi: Complete.

H9EUD5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSGLWSQEK VTSPYWEERI FYLLLQECSV TDKQTQKLLK VPKGSIGQYI
60 70 80 90 100
QDRSVGHSRI PSAKGKKNQI GLKILEQPHA VLFVDEKDVA EINEKFTELL
110 120 130 140 150
LAITNCEERF SLFKNRNRLS KGLQIDVGCP VKVQLRSGEE KFPGVVRFRG
160 170 180 190 200
PLLAERTVSG IFFGVELLEE GRGQGFTDGV YQGKQLFQCD EDCGVFVALD
210 220 230 240 250
KLELIEDDDT ALESDYAGPV DTMQVELPPL EINSRVSLKV GETIESGTVI
260 270 280 290 300
FCDVLPGKES LGYFVGVDMD NPIGNWDGRF DGVQLCSFAC VESTILLHIN
310 320 330 340 350
DIIPESVSQE RRPPKLAFMS RGVGDKGSSS HNKPKATGST SDPGNRNRSE
360 370 380 390 400
LFYTLNGSSV DSQPQSKSKN TWYIDEVAED PAKSLTEIST DFDRSSPPLQ
410 420 430 440 450
PPPVNSLSTE NRFHSLPFSL TKMPNTNGSI GHSPLSLSAQ SVMEELNTAP
460 470 480 490 500
VQESPPLAMP PGNSHGLEVG SLAEVKENPP FYGVIRWIGQ PPGLNEVLAG
510 520 530 540 550
LELEDECAGC TDGTFRGTRY FTCALKKALF VKLKSCRPDS RFASLQPVSN
560 570 580 590 600
QIERCNSLAF GGYLSEVVEE NTPPKMEKEG LEIMIGKKKG IQGHYNSCYL
610 620 630 640 650
DSTLFCLFAF SSVLDTVLLR PKEKNDVEYY SETQELLRTE IVNPLRIYGY
660 670 680 690 700
VCATKIMKLR KILEKVEAAS GFTSEEKDPE EFLNILFHHI LRVEPLLKIR
710 720 730 740 750
SAGQKVQDCY FYQIFMEKNE KVGVPTIQQL LEWSFINSNL KFAEAPSCLI
760 770 780 790 800
IQMPRFGKDF KLFKKIFPSL ELNITDLLED TPRQCRICGG LAMYECRECY
810 820 830 840 850
DDPDISAGKI KQFCKTCNTQ VHLHPKRLNH KYNPVSLPKD LPDWDWRHGC
860 870 880 890 900
IPCQKMELFA VLCIETSHYV AFVKYGKDDS AWLFFDSMAD RDGGQNGFNI
910 920 930 940 950
PQVTPCPEVG EYLKMSLEDL HSLDSRRIQG CARRLLCDAY MCMYQSPTMS

LYK
Length:953
Mass (Da):107,044
Last modified:May 16, 2012 - v1
Checksum:i01DEE3731B063FA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03026196 Genomic DNA. No translation available.
JU322238 mRNA. Translation: AFE65994.1.
JU471648 mRNA. Translation: AFH28452.1.
RefSeqiXP_014981598.1. XM_015126112.1.
XP_014981599.1. XM_015126113.1.
UniGeneiMmu.20842.

Genome annotation databases

EnsembliENSMMUT00000078247; ENSMMUP00000057215; ENSMMUG00000012209.
GeneIDi695652.

Similar proteinsi

Entry informationi

Entry nameiH9EUD5_MACMU
AccessioniPrimary (citable) accession number: H9EUD5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: October 25, 2017
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported