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Protein
Submitted name:

Eukaryotic translation initiation factor 1A, X-chromosomal

Gene

EIF1AY

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factorPROSITE-ProRule annotationImported
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 1A, X-chromosomalImported
Gene namesi
Name:EIF1AYImported
Synonyms:EIF1AXImported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Structurei

3D structure databases

SMRiH9EP53.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 96S1-likeInterPro annotationAdd BLAST75

Sequence similaritiesi

Belongs to the eIF-1A family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3403. Eukaryota.
COG0361. LUCA.
KOiK03236.

Family and domain databases

CDDicd05793. S1_IF1A. 1 hit.
HAMAPiMF_00216. aIF_1A. 1 hit.
InterProiView protein in InterPro
IPR012340. NA-bd_OB-fold.
IPR006196. RNA-binding_domain_S1_IF1.
IPR001253. TIF_eIF-1A.
IPR018104. TIF_eIF-1A_CS.
PANTHERiPTHR21668. PTHR21668. 1 hit.
PfamiView protein in Pfam
PF01176. eIF-1a. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD005579. TIF_eIF-1A. 1 hit.
SMARTiView protein in SMART
SM00652. eIF1a. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00523. eIF-1A. 1 hit.
PROSITEiView protein in PROSITE
PS01262. IF1A. 1 hit.
PS50832. S1_IF1_TYPE. 1 hit.

Sequencei

Sequence statusi: Complete.

H9EP53-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKNKGKGGK NRRRGKNENE SEKRELVFKE DGQEYAQVIK MLGNGRLEAM
60 70 80 90 100
CFDGVKRLCH IRGKLRKKVW INTSDIILVG LRDYQDNKAD VILKYNADEA
110 120 130 140
RSLKAYGELP EHAKINETDT FGPGDDDEIQ FDDIGDDDED IDDI
Length:144
Mass (Da):16,460
Last modified:May 16, 2012 - v1
Checksum:i1C4209855B21BFD4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JU320405 mRNA. Translation: AFE64161.1.
JU320406 mRNA. Translation: AFE64162.1.
JU333281 mRNA. Translation: AFE77036.1.
JU474591 mRNA. Translation: AFH31395.1.
JV046373 mRNA. Translation: AFI36444.1.
RefSeqiNP_001248706.1. NM_001261777.1.
UniGeneiMmu.2420.

Genome annotation databases

GeneIDi695456.
KEGGimcc:695456.

Similar proteinsi

Entry informationi

Entry nameiH9EP53_MACMU
AccessioniPrimary (citable) accession number: H9EP53
Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: September 27, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)