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Protein

Importin subunit alpha

Gene

KPNA6

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Functions in nuclear protein import.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Importin subunit alphaUniRule annotation
Gene namesi
Name:KPNA6Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Structurei

3D structure databases

SMRiH9EN17.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 60IBBInterPro annotationAdd BLAST60
Repeati124 – 167ARMPROSITE-ProRule annotationAdd BLAST44
Repeati167 – 195ARMPROSITE-ProRule annotationAdd BLAST29
Repeati336 – 367ARMPROSITE-ProRule annotationAdd BLAST32

Sequence similaritiesi

Belongs to the importin alpha family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0166. Eukaryota.
COG5064. LUCA.
OMAiNLGCIKP.
TreeFamiTF354205.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR032413. Arm_3.
IPR000225. Armadillo.
IPR002652. Importin-a_IBB.
IPR024931. Importing_su_alpha.
PfamiView protein in Pfam
PF00514. Arm. 8 hits.
PF16186. Arm_3. 1 hit.
PF01749. IBB. 1 hit.
PIRSFiPIRSF005673. Importin_alpha. 1 hit.
SMARTiView protein in SMART
SM00185. ARM. 8 hits.
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiView protein in PROSITE
PS50176. ARM_REPEAT. 3 hits.
PS51214. IBB. 1 hit.

Sequencei

Sequence statusi: Complete.

H9EN17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METMASPGKD NYRMKSYKNN ALNPEEMRRR REEEGIQLRK QKREQQLFKR
60 70 80 90 100
RNVELINEEA AMFDSLLMDS YVSSTTGESV ITREMVEMLF SDDSDLQLAT
110 120 130 140 150
TQKFRKLLSK EPSPPIDEVI NTPRVVDRFV EFLKRNENCT LQFEAAWALT
160 170 180 190 200
NIASGTSQQT KIVIEAGAVP IFIELLNSDF EDVQEQAVWA LGNIAGDSSV
210 220 230 240 250
CRDYVLNCSI LNPLLTLLTK STRLTMTRNA VWALSNLCRG KNPPPEFAKV
260 270 280 290 300
SPCLPVLSRL LFSSDSDLLA DACWALSYLS DGPNEKIQAV IDSGVCRRLV
310 320 330 340 350
ELLMHNDYKV ASPALRAVGN IVTGDDIQTQ VILNCSALPC LLHLLSSPKE
360 370 380 390 400
SIRKEACWTI SNITAGNRAQ IQAVIDANIF PVLIEILQKA EFRTRKEAAW
410 420 430 440 450
AITNATSGGT PEQIRYLVSL GCIKPLCDLL TVMDSKIVQV ALNGLENILR
460 470 480 490 500
LGEQEGKRSG SGVNPYCGLI EEAYGLDKIE FLQSHENQEI YQKAFDLIEH
510 520 530
YFGVEDDDSS LAPQVDETQQ QFIFQQPEAP MEGFQL
Length:536
Mass (Da):60,030
Last modified:November 30, 2016 - v1
Checksum:i9D0E27482B9BDED3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JU320020 mRNA. Translation: AFE63776.1.
JU320021 mRNA. Translation: AFE63777.1.
JU320022 mRNA. Translation: AFE63778.1.
JU332148 mRNA. Translation: AFE75904.1.
JU472092 mRNA. Translation: AFH28896.1.
JV046621 mRNA. Translation: AFI36692.1.
RefSeqiNP_001253921.1. NM_001266992.1.
UniGeneiMmu.640.

Genome annotation databases

GeneIDi706812.
KEGGimcc:706812.

Similar proteinsi

Entry informationi

Entry nameiH9EN17_MACMU
AccessioniPrimary (citable) accession number: H9EN17
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2016
Last sequence update: November 30, 2016
Last modified: August 30, 2017
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)