H8ZRU2 (H8ZRU2_9HELO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Laccase EMBL AFC76164.1
Organism	Botrytis aclada EMBL AFC76164.1
Taxonomic identifier	139639 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › sordariomyceta › Leotiomycetes › Helotiales › Sclerotiniaceae › mitosporic Sclerotiniaceae › Botrytis

Protein attributes

Sequence length	580 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Copper SAAS SAAS011706 Metal-binding SAAS SAAS011706
Molecular function	Oxidoreductase SAAS SAAS011706
Technical term	3D-structure PDB 3SQR
Gene Ontology (GO)
Molecular_function	copper ion binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H8ZRU2 [UniParc]. Last modified May 16, 2012. Version 1. Checksum: 32A1C1C8C0BDA0F5	FASTA	580	63,629
	10 20 30 40 50 60 MKYFTVFTAL TALFAQASAS AIPAVRSTLT PRQNTTASCA NSATSRSCWG EYSIDTNWYD 70 80 90 100 110 120 VTPTGVTREY WLSVENSTIT PDGYTRSAMT FNGTVPGPAI IADWGDNLII HVTNNLEHNG 130 140 150 160 170 180 TSIHWHGIRQ LGSLEYDGVP GVTQCPIAPG DTLTYKFQVT QYGTTWYHSH FSLQYGDGLF 190 200 210 220 230 240 GPLIINGPAT ADYDEDVGVI FLQDWAHESV FEIWDTARLG APPALENTLM NGTNTFDCSA 250 260 270 280 290 300 STDPNCVGGG KKFELTFVEG TKYRLRLINV GIDSHFEFAI DNHTLTVIAN DLVPIVPYTT 310 320 330 340 350 360 DTLLIGIGQR YDVIVEANAA ADNYWIRGNW GTTCSTNNEA ANATGILRYD SSSIANPTSV 370 380 390 400 410 420 GTTPRGTCED EPVASLVPHL ALDVGGYSLV DEQVSSAFTN YFTWTINSSS LLLDWSSPTT 430 440 450 460 470 480 LKIFNNETIF PTEYNVVALE QTNANEEWVV YVIEDLTGFG IWHPIHLHGH DFFIVAQETD 490 500 510 520 530 540 VFNSDESPAK FNLVNPPRRD VAALPGNGYL AIAFKLDNPG SWLLHCHIAW HASEGLAMQF 550 560 570 580 VESQSSIAVK MTDTAIFEDT CANWNAYTPT QLFAEDDSGI

References

[1]	"Structural and kinetic characterization of a chloride resistant laccase from Botrytis aclada." Osipov E.M., Polyakov K.M., Tikhonova T.V., Dorovatovsky P.V., Ludwig R., Kittl R., Shleev S.V., Popov V.O. Submitted (JUL-2011) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.67 ANGSTROMS).
[2]	"A chloride tolerant laccase from the plant pathogen ascomycete Botrytis aclada expressed at high levels in Pichia pastoris." Kittl R., Mueangtoom K., Gonaus C., Khazaneh S.T., Sygmund C., Haltrich D., Ludwig R. J. Biotechnol. 157:304-314(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

JN559771 Genomic DNA. Translation: AFC76164.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3SQR	X-ray	1.67	A	1-580	[»]

ModBase

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Protocols and materials databases

StructuralBiologyKnowledgebase

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Family and domain databases

Gene3D

2.60.40.420. 3 hits.

InterPro

IPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
[Graphical view]

Pfam

PF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]

SUPFAM

SSF49503. Cupredoxin. 3 hits.

PROSITE

PS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

ProtoNet

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Entry information

Entry name

H8ZRU2_9HELO

Accession

Primary (citable) accession number: H8ZRU2

Entry history

Integrated into UniProtKB/TrEMBL:	May 16, 2012
Last sequence update:	May 16, 2012
Last modified:	March 6, 2013
This is version 6 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)