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H8ZRU2

- H8ZRU2_9HELO

UniProt

H8ZRU2 - H8ZRU2_9HELO

Protein
Submitted name:

Laccase

Gene
N/A
Organism
Botrytis aclada
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (16 May 2012)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi126 – 1261Copper 1; via pros nitrogenImported
    Metal bindingi168 – 1681Copper 1; via tele nitrogenImported
    Metal bindingi170 – 1701Copper 2; via tele nitrogenImported
    Metal bindingi463 – 4631Copper 3; via pros nitrogenImported
    Metal bindingi466 – 4661Copper 2; via pros nitrogenImported
    Metal bindingi468 – 4681Copper 2; via tele nitrogenImported
    Metal bindingi525 – 5251Copper 2; via tele nitrogenImported
    Metal bindingi526 – 5261Copper 3Imported
    Metal bindingi527 – 5271Copper 1; via tele nitrogenImported
    Metal bindingi531 – 5311Copper 3; via pros nitrogenImported

    GO - Molecular functioni

    1. copper ion binding Source: InterPro
    2. oxidoreductase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseSAAS annotation

    Keywords - Ligandi

    CopperSAAS annotationImported, Metal-bindingSAAS annotationImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    LaccaseImported
    OrganismiBotrytis acladaImported
    Taxonomic identifieri139639 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaLeotiomycetesHelotialesSclerotiniaceaeBotrytis

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi76 – 761N-linked (GlcNAc...)Imported
    Glycosylationi92 – 921N-linked (GlcNAc...)Imported
    Glycosylationi119 – 1191N-linked (GlcNAc...)Imported
    Glycosylationi231 – 2311N-linked (GlcNAc...)Imported
    Glycosylationi342 – 3421N-linked (GlcNAc...)Imported
    Glycosylationi375 – 3751O-linked (Man...)Imported
    Glycosylationi407 – 4071N-linked (GlcNAc...)Imported
    Glycosylationi426 – 4261N-linked (GlcNAc...)Imported

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3SQRX-ray1.67A1-580[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di2.60.40.420. 3 hits.
    InterProiIPR001117. Cu-oxidase.
    IPR011706. Cu-oxidase_2.
    IPR011707. Cu-oxidase_3.
    IPR002355. Cu_oxidase_Cu_BS.
    IPR008972. Cupredoxin.
    [Graphical view]
    PfamiPF00394. Cu-oxidase. 1 hit.
    PF07731. Cu-oxidase_2. 1 hit.
    PF07732. Cu-oxidase_3. 1 hit.
    [Graphical view]
    SUPFAMiSSF49503. SSF49503. 3 hits.
    PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
    PS00080. MULTICOPPER_OXIDASE2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H8ZRU2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKYFTVFTAL TALFAQASAS AIPAVRSTLT PRQNTTASCA NSATSRSCWG    50
    EYSIDTNWYD VTPTGVTREY WLSVENSTIT PDGYTRSAMT FNGTVPGPAI 100
    IADWGDNLII HVTNNLEHNG TSIHWHGIRQ LGSLEYDGVP GVTQCPIAPG 150
    DTLTYKFQVT QYGTTWYHSH FSLQYGDGLF GPLIINGPAT ADYDEDVGVI 200
    FLQDWAHESV FEIWDTARLG APPALENTLM NGTNTFDCSA STDPNCVGGG 250
    KKFELTFVEG TKYRLRLINV GIDSHFEFAI DNHTLTVIAN DLVPIVPYTT 300
    DTLLIGIGQR YDVIVEANAA ADNYWIRGNW GTTCSTNNEA ANATGILRYD 350
    SSSIANPTSV GTTPRGTCED EPVASLVPHL ALDVGGYSLV DEQVSSAFTN 400
    YFTWTINSSS LLLDWSSPTT LKIFNNETIF PTEYNVVALE QTNANEEWVV 450
    YVIEDLTGFG IWHPIHLHGH DFFIVAQETD VFNSDESPAK FNLVNPPRRD 500
    VAALPGNGYL AIAFKLDNPG SWLLHCHIAW HASEGLAMQF VESQSSIAVK 550
    MTDTAIFEDT CANWNAYTPT QLFAEDDSGI 580
    Length:580
    Mass (Da):63,629
    Last modified:May 16, 2012 - v1
    Checksum:i32A1C1C8C0BDA0F5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JN559771 Genomic DNA. Translation: AFC76164.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JN559771 Genomic DNA. Translation: AFC76164.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3SQR X-ray 1.67 A 1-580 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.60.40.420. 3 hits.
    InterProi IPR001117. Cu-oxidase.
    IPR011706. Cu-oxidase_2.
    IPR011707. Cu-oxidase_3.
    IPR002355. Cu_oxidase_Cu_BS.
    IPR008972. Cupredoxin.
    [Graphical view ]
    Pfami PF00394. Cu-oxidase. 1 hit.
    PF07731. Cu-oxidase_2. 1 hit.
    PF07732. Cu-oxidase_3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49503. SSF49503. 3 hits.
    PROSITEi PS00079. MULTICOPPER_OXIDASE1. 1 hit.
    PS00080. MULTICOPPER_OXIDASE2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural and kinetic characterization of a chloride resistant laccase from Botrytis aclada."
      Osipov E.M., Polyakov K.M., Tikhonova T.V., Dorovatovsky P.V., Ludwig R., Kittl R., Shleev S.V., Popov V.O.
      Submitted (JUL-2011) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.67 ANGSTROMS) IN COMPLEX WITH COPPER, GLYCOSYLATION AT ASN-76; ASN-92; ASN-119; ASN-231; ASN-342; SER-375; ASN-407 AND ASN-426.
    2. "A chloride tolerant laccase from the plant pathogen ascomycete Botrytis aclada expressed at high levels in Pichia pastoris."
      Kittl R., Mueangtoom K., Gonaus C., Khazaneh S.T., Sygmund C., Haltrich D., Ludwig R.
      J. Biotechnol. 157:304-314(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiH8ZRU2_9HELO
    AccessioniPrimary (citable) accession number: H8ZRU2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 16, 2012
    Last sequence update: May 16, 2012
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3