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H8XES9

- H8XES9_BACAM

UniProt

H8XES9 - H8XES9_BACAM

Protein

Isocitrate dehydrogenase [NADP]

Gene

citC

Organism
Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (16 May 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciBAMY1155777:GL8E-2922-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:citCImported
    ORF Names:BANAU_2832Imported
    OrganismiBacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2Imported
    Taxonomic identifieri1155777 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000007598: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H8XES9-1 [UniParc]FASTAAdd to Basket

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    MSQGEKITVS NGVLNVPNNP IIPFIEGDGT GPDIWNAASK VLEAAVEKAY    50
    KGEKKITWKE VYAGEKAYNK TGEWLPAKTL EDIREYFIAI KGPLTTPVGG 100
    GIRSLNVALR QELDLFTCLR PVRYFTGVPS PVKRPEDTDM VIFRENTEDI 150
    YAGIEYAKGS EEVEKLISFL QNEMGVNKIR FPETSGIGIK PVSEEGTSRL 200
    VRAAIEYAIE NGRKSVTLVH KGNIMKFTEG AFKNWGYELA EREYGDKVFT 250
    WAEYDRIVEK DGKEAADKAQ SDAEAAGKII VKDSIADIFL QQILTRPSEF 300
    DVVATMNLNG DYISDALAAQ VGGIGIAPGA NINYETGHAI FEATHGTAPK 350
    YAGLDKVNPS SVILSGVLLL EHLNWNEAAD LIIKSMEKTI ASKVVTYDFA 400
    RLMDGATEVK CSEFGEELIK NMD 423
    Length:423
    Mass (Da):46,492
    Last modified:May 16, 2012 - v1
    Checksum:i3D20AAE8F3EDE929
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE774679 Genomic DNA. Translation: CCG50853.1.
    RefSeqiYP_005422169.1. NC_017061.1.

    Genome annotation databases

    EnsemblBacteriaiCCG50853; CCG50853; BANAU_2832.
    GeneIDi12208336.
    KEGGibya:BANAU_2832.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE774679 Genomic DNA. Translation: CCG50853.1 .
    RefSeqi YP_005422169.1. NC_017061.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CCG50853 ; CCG50853 ; BANAU_2832 .
    GeneIDi 12208336.
    KEGGi bya:BANAU_2832.

    Phylogenomic databases

    KOi K00031.

    Enzyme and pathway databases

    BioCyci BAMY1155777:GL8E-2922-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The Genome of Plant Growth-Promoting Bacillus amyloliquefaciens subsp. plantarum Strain YAU B9601-Y2 Contains a Gene Cluster for Mersacidin Synthesis."
      Hao K., He P., Blom J., Rueckert C., Mao Z., Wu Y., He Y., Borriss R.
      J. Bacteriol. 194:3264-3265(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: YAU B9601-Y2Imported.

    Entry informationi

    Entry nameiH8XES9_BACAM
    AccessioniPrimary (citable) accession number: H8XES9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 16, 2012
    Last sequence update: May 16, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3