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H8XES9

- H8XES9_BACAM

UniProt

H8XES9 - H8XES9_BACAM

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Protein

Isocitrate dehydrogenase [NADP]

Gene

citC

Organism
Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit.

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciBAMY1155777:GL8E-2922-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:citCImported
ORF Names:BANAU_2832Imported
OrganismiBacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2Imported
Taxonomic identifieri1155777 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000007598: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8XES9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSQGEKITVS NGVLNVPNNP IIPFIEGDGT GPDIWNAASK VLEAAVEKAY
60 70 80 90 100
KGEKKITWKE VYAGEKAYNK TGEWLPAKTL EDIREYFIAI KGPLTTPVGG
110 120 130 140 150
GIRSLNVALR QELDLFTCLR PVRYFTGVPS PVKRPEDTDM VIFRENTEDI
160 170 180 190 200
YAGIEYAKGS EEVEKLISFL QNEMGVNKIR FPETSGIGIK PVSEEGTSRL
210 220 230 240 250
VRAAIEYAIE NGRKSVTLVH KGNIMKFTEG AFKNWGYELA EREYGDKVFT
260 270 280 290 300
WAEYDRIVEK DGKEAADKAQ SDAEAAGKII VKDSIADIFL QQILTRPSEF
310 320 330 340 350
DVVATMNLNG DYISDALAAQ VGGIGIAPGA NINYETGHAI FEATHGTAPK
360 370 380 390 400
YAGLDKVNPS SVILSGVLLL EHLNWNEAAD LIIKSMEKTI ASKVVTYDFA
410 420
RLMDGATEVK CSEFGEELIK NMD
Length:423
Mass (Da):46,492
Last modified:May 16, 2012 - v1
Checksum:i3D20AAE8F3EDE929
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE774679 Genomic DNA. Translation: CCG50853.1.
RefSeqiYP_005422169.1. NC_017061.1.

Genome annotation databases

EnsemblBacteriaiCCG50853; CCG50853; BANAU_2832.
GeneIDi12208336.
KEGGibya:BANAU_2832.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE774679 Genomic DNA. Translation: CCG50853.1 .
RefSeqi YP_005422169.1. NC_017061.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCG50853 ; CCG50853 ; BANAU_2832 .
GeneIDi 12208336.
KEGGi bya:BANAU_2832.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci BAMY1155777:GL8E-2922-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The Genome of Plant Growth-Promoting Bacillus amyloliquefaciens subsp. plantarum Strain YAU B9601-Y2 Contains a Gene Cluster for Mersacidin Synthesis."
    Hao K., He P., Blom J., Rueckert C., Mao Z., Wu Y., He Y., Borriss R.
    J. Bacteriol. 194:3264-3265(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YAU B9601-Y2Imported.

Entry informationi

Entry nameiH8XES9_BACAM
AccessioniPrimary (citable) accession number: H8XES9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: October 29, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3