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H8XCR3

- H8XCR3_BACAM

UniProt

H8XCR3 - H8XCR3_BACAM

Protein

Alanine racemase

Gene

yncD

Organism
Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (16 May 2012)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei39 – 391Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei139 – 1391SubstrateUniRule annotation
    Active sitei272 – 2721Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei320 – 3201Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciBAMY1155777:GL8E-2494-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:yncDImported
    ORF Names:BANAU_2407Imported
    OrganismiBacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2Imported
    Taxonomic identifieri1155777 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000007598: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei39 – 391N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliH8XCR3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H8XCR3-1 [UniParc]FASTAAdd to Basket

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    MKKLCREVWI EVDLDAIKKN VRAIRRHIPN TSKIMAVVKA NAYGHGSVEV    50
    ARQALESGAS ELAVASVEEG IVLRRAGITA PILVLGFTAL SCVKKSAVWN 100
    ITLSAFQVSW IKKANRILEK EADSKRLSIH INVDTGMGRL GVRTEEDLLA 150
    VVKALKSSTY LSWDGIFTHF STADEPDTEL TMLQHEKFIS FLRFLKNQDI 200
    TLPTVHMCNT AAAIAFPEFS ADMIRLGIGL YGLYPSASIK ELNLVDLTPA 250
    LSLKARIAYV KAMVTDPRTV SYGATYIAEP GEIIATIPIG YADGYSRALS 300
    NRGFILHRGR RVPVAGRVTM DMIMVSLGEN EGKQGEEVVI YGKQQGAEIS 350
    VDEIAEMLGT ISYEVLSVLS RRVPRFYFRD GKIIKISAPV LYV 393
    Length:393
    Mass (Da):43,293
    Last modified:May 16, 2012 - v1
    Checksum:iEDB36896A239C1ED
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE774679 Genomic DNA. Translation: CCG50428.1.
    RefSeqiYP_005421744.1. NC_017061.1.

    Genome annotation databases

    EnsemblBacteriaiCCG50428; CCG50428; BANAU_2407.
    GeneIDi12205770.
    KEGGibya:BANAU_2407.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE774679 Genomic DNA. Translation: CCG50428.1 .
    RefSeqi YP_005421744.1. NC_017061.1.

    3D structure databases

    ProteinModelPortali H8XCR3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CCG50428 ; CCG50428 ; BANAU_2407 .
    GeneIDi 12205770.
    KEGGi bya:BANAU_2407.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci BAMY1155777:GL8E-2494-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The Genome of Plant Growth-Promoting Bacillus amyloliquefaciens subsp. plantarum Strain YAU B9601-Y2 Contains a Gene Cluster for Mersacidin Synthesis."
      Hao K., He P., Blom J., Rueckert C., Mao Z., Wu Y., He Y., Borriss R.
      J. Bacteriol. 194:3264-3265(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: YAU B9601-Y2Imported.

    Entry informationi

    Entry nameiH8XCR3_BACAM
    AccessioniPrimary (citable) accession number: H8XCR3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 16, 2012
    Last sequence update: May 16, 2012
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3