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H8XCR3

- H8XCR3_BACAM

UniProt

H8XCR3 - H8XCR3_BACAM

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Protein

Alanine racemase

Gene

yncD

Organism
Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei139 – 1391SubstrateUniRule annotation
Active sitei272 – 2721Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei320 – 3201Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBAMY1155777:GL8E-2494-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:yncDImported
ORF Names:BANAU_2407Imported
OrganismiBacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2Imported
Taxonomic identifieri1155777 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000007598: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei39 – 391N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliH8XCR3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8XCR3 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKLCREVWI EVDLDAIKKN VRAIRRHIPN TSKIMAVVKA NAYGHGSVEV
60 70 80 90 100
ARQALESGAS ELAVASVEEG IVLRRAGITA PILVLGFTAL SCVKKSAVWN
110 120 130 140 150
ITLSAFQVSW IKKANRILEK EADSKRLSIH INVDTGMGRL GVRTEEDLLA
160 170 180 190 200
VVKALKSSTY LSWDGIFTHF STADEPDTEL TMLQHEKFIS FLRFLKNQDI
210 220 230 240 250
TLPTVHMCNT AAAIAFPEFS ADMIRLGIGL YGLYPSASIK ELNLVDLTPA
260 270 280 290 300
LSLKARIAYV KAMVTDPRTV SYGATYIAEP GEIIATIPIG YADGYSRALS
310 320 330 340 350
NRGFILHRGR RVPVAGRVTM DMIMVSLGEN EGKQGEEVVI YGKQQGAEIS
360 370 380 390
VDEIAEMLGT ISYEVLSVLS RRVPRFYFRD GKIIKISAPV LYV
Length:393
Mass (Da):43,293
Last modified:May 16, 2012 - v1
Checksum:iEDB36896A239C1ED
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE774679 Genomic DNA. Translation: CCG50428.1.
RefSeqiYP_005421744.1. NC_017061.1.

Genome annotation databases

EnsemblBacteriaiCCG50428; CCG50428; BANAU_2407.
GeneIDi12205770.
KEGGibya:BANAU_2407.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE774679 Genomic DNA. Translation: CCG50428.1 .
RefSeqi YP_005421744.1. NC_017061.1.

3D structure databases

ProteinModelPortali H8XCR3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCG50428 ; CCG50428 ; BANAU_2407 .
GeneIDi 12205770.
KEGGi bya:BANAU_2407.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci BAMY1155777:GL8E-2494-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The Genome of Plant Growth-Promoting Bacillus amyloliquefaciens subsp. plantarum Strain YAU B9601-Y2 Contains a Gene Cluster for Mersacidin Synthesis."
    Hao K., He P., Blom J., Rueckert C., Mao Z., Wu Y., He Y., Borriss R.
    J. Bacteriol. 194:3264-3265(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YAU B9601-Y2Imported.

Entry informationi

Entry nameiH8XCR3_BACAM
AccessioniPrimary (citable) accession number: H8XCR3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: October 29, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3