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H8WV95

- H8WV95_HUMAN

UniProt

H8WV95 - H8WV95_HUMAN

Protein
Submitted name:

MHC class II antigen

Gene

HLA-DRB1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
    2. immune response Source: InterPro

    Keywords - Biological processi

    Immunity

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MHC class II antigenImported
    Gene namesi
    Name:HLA-DRB1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. MHC class II protein complex Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane, MHC IIUniRule annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiH8WV95.

    Expressioni

    Gene expression databases

    ArrayExpressiH8WV95.
    BgeeiH8WV95.

    Structurei

    3D structure databases

    ProteinModelPortaliH8WV95.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    TransmembraneUniRule annotation

    Family and domain databases

    Gene3Di3.10.320.10. 1 hit.
    InterProiIPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR000353. MHC_II_b_N.
    [Graphical view]
    PfamiPF00969. MHC_II_beta. 1 hit.
    [Graphical view]
    ProDomiPD000328. MHC_II_b_N. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SMARTiSM00921. MHC_II_beta. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    H8WV95-1 [UniParc]FASTAAdd to Basket

    « Hide

    RFLWQPKREC HFFNGTERVR FLDRYFYNQE ESVRFDSDVG EFRAVTELGR   50
    PDAEYWNSQK DILEQARAAV DTYCRHNYGV VESFTVQRR 89
    Length:89
    Mass (Da):10,834
    Last modified:May 16, 2012 - v1
    Checksum:iB0DADC7D8884DEA9
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei89 – 891Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE654767 Genomic DNA. Translation: CCF77340.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE654767 Genomic DNA. Translation: CCF77340.1 .

    3D structure databases

    ProteinModelPortali H8WV95.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi H8WV95.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi HLA-DRB1. human.
    NextBioi 35530739.

    Gene expression databases

    ArrayExpressi H8WV95.
    Bgeei H8WV95.

    Family and domain databases

    Gene3Di 3.10.320.10. 1 hit.
    InterProi IPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR000353. MHC_II_b_N.
    [Graphical view ]
    Pfami PF00969. MHC_II_beta. 1 hit.
    [Graphical view ]
    ProDomi PD000328. MHC_II_b_N. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SMARTi SM00921. MHC_II_beta. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. BGI HLA novel-allele working group
      Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Characterization of 27 novel HLA class II alleles from China marrow donor program."
      Zhang C., Wang Y., Huang C., Zhang M., Chen C., Cao H., Chai X., Li J.
      Tissue Antigens 82:201-202(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiH8WV95_HUMAN
    AccessioniPrimary (citable) accession number: H8WV95
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 16, 2012
    Last sequence update: May 16, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.