ID   H8WV93_HUMAN            Unreviewed;        89 AA.
AC   H8WV93;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   16-MAY-2012, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=MHC class II antigen {ECO:0000313|EMBL:CCF77338.1};
DE   Flags: Fragment;
GN   Name=HLA-DRB1 {ECO:0000313|EMBL:CCF77338.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:CCF77338.1};
RN   [1] {ECO:0000313|EMBL:CCF77338.1}
RP   NUCLEOTIDE SEQUENCE.
RG   BGI HLA novel-allele working group;
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCF77338.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23826662; DOI=10.1111/tan.12167;
RA   Zhang C., Wang Y., Huang C., Zhang M., Chen C., Cao H., Chai X., Li J.;
RT   "Characterization of 27 novel HLA class II alleles from China marrow donor
RT   program.";
RL   Tissue Antigens 82:201-202(2013).
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DR   EMBL; HE654765; CCF77338.1; -; Genomic_DNA.
DR   AlphaFoldDB; H8WV93; -.
DR   PeptideAtlas; H8WV93; -.
DR   ChiTaRS; HLA-DRB1; human.
DR   GO; GO:0042613; C:MHC class II protein complex; IEA:InterPro.
DR   GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR014745; MHC_II_a/b_N.
DR   InterPro; IPR000353; MHC_II_b_N.
DR   Pfam; PF00969; MHC_II_beta; 1.
DR   SMART; SM00921; MHC_II_beta; 1.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          8..83
FT                   /note="MHC class II beta chain N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00921"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CCF77338.1"
FT   NON_TER         89
FT                   /evidence="ECO:0000313|EMBL:CCF77338.1"
SQ   SEQUENCE   89 AA;  10403 MW;  4C02F3C44A011550 CRC64;
     RFLEYSTSEC HFFNGTERVR FLDRYFHNQE EFVRFDSDVG EYRAVTELGR PAAEHWNSQK
     DLLEQKRGRG GHLLQTQLRG CGELHSAAA
//