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H8WV92

- H8WV92_HUMAN

UniProt

H8WV92 - H8WV92_HUMAN

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Protein
Submitted name: MHC class II antigen
Gene
HLA-DRB1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Biological processi

  1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
  2. immune response Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Immunity

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class II antigenImported
Gene namesi
Name:HLA-DRB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. MHC class II protein complex Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, MHC IIUniRule annotation

Family & Domainsi

Keywords - Domaini

TransmembraneUniRule annotation

Family and domain databases

Gene3Di3.10.320.10. 1 hit.
InterProiIPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view]
PfamiPF00969. MHC_II_beta. 1 hit.
[Graphical view]
ProDomiPD000328. MHC_II_b_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00921. MHC_II_beta. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.

Sequencei

Sequence statusi: Fragment.

H8WV92-1 [UniParc]FASTAAdd to Basket

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RFLEYSTSEC HFFNGTERVR FLDRYFHNQE EFVRFDSDVG EYRAVTELGR   50
PAAEHWNSRK DLLERRRAEV DTYCRHNYGV VESFTVQRR 89
Length:89
Mass (Da):10,885
Last modified:May 16, 2012 - v1
Checksum:i4273BDE3D7340C32
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei89 – 891Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE654764 Genomic DNA. Translation: CCF77337.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE654764 Genomic DNA. Translation: CCF77337.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi HLA-DRB1. human.
NextBioi 35530736.

Family and domain databases

Gene3Di 3.10.320.10. 1 hit.
InterProi IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view ]
Pfami PF00969. MHC_II_beta. 1 hit.
[Graphical view ]
ProDomi PD000328. MHC_II_b_N. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00921. MHC_II_beta. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
ProtoNeti Search...

Publicationsi

  1. BGI HLA novel-allele working group
    Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Characterization of 27 novel HLA class II alleles from China marrow donor program."
    Zhang C., Wang Y., Huang C., Zhang M., Chen C., Cao H., Chai X., Li J.
    Tissue Antigens 82:201-202(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiH8WV92_HUMAN
AccessioniPrimary (citable) accession number: H8WV92
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: July 9, 2014
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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