SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

H8N2K8

- H8N2K8_RICPO

UniProt

H8N2K8 - H8N2K8_RICPO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alanine racemase

Gene
alr, M9W_00450
Organism
Rickettsia prowazekii str. Chernikova
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei34 – 341Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei133 – 1331Substrate By similarityUniRule annotation
Active sitei298 – 2981Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei346 – 3461Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciRPRO1105094:GLJE-89-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
ORF Names:M9W_00450Imported
OrganismiRickettsia prowazekii str. ChernikovaImported
Taxonomic identifieri1105094 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000007586: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei34 – 341N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliH8N2K8.

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
IPR005728. Rickett_RPE.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR01045. RPE1. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8N2K8-1 [UniParc]FASTAAdd to Basket

« Hide

MSLCTLEINL SAIKNNYRLL QDICKTALVG AVVKANGYGL GAMQIAKALI    50
KENCQYFFVA TSEEGINLRK VLNNDITILV LNGVFTHDAL ELIQYNLTPV 100
LNNLSQIEIW QKFSNLKGKI LPCYLHFNTG LNRFGLNSDE IEQLINDRDL 150
LKGLDLQYII SHLAASEETG NPYNLIQLNR FKVYLEYFPN VKASFANSGG 200
IFLGQDYHFD LARPGAALYG LNSLIEVSSN LSYTEEFESN TAALTTTACI 250
NKCPDVSVRL TPKLPLKGSY TVRLQNPVTL KAPIIDLQNL TLDSHIGYNM 300
TFTTKRDSVI ATLPLGYADG FSRNFSSQGE VFINSCRVPI VGRVSMDLIN 350
IDVTDLPPSE VFLGQEAEII GNYCTPDKIA SIIGTIGYEV LTSLGSRYKR 400
KYIS 404
Length:404
Mass (Da):44,799
Last modified:May 16, 2012 - v1
Checksum:i0BA23D87D832576B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003391 Genomic DNA. Translation: AFE48919.1.
RefSeqiYP_005405197.1. NC_017049.1.

Genome annotation databases

EnsemblBacteriaiAFE48919; AFE48919; M9W_00450.
GeneIDi12007843.
KEGGirpw:M9W_00450.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003391 Genomic DNA. Translation: AFE48919.1 .
RefSeqi YP_005405197.1. NC_017049.1.

3D structure databases

ProteinModelPortali H8N2K8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFE48919 ; AFE48919 ; M9W_00450 .
GeneIDi 12007843.
KEGGi rpw:M9W_00450.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci RPRO1105094:GLJE-89-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
IPR005728. Rickett_RPE.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR01045. RPE1. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Johnson S.L., Munk A.C., Han S., Bruce D.C., Dasch G.A.
    Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ChernikovaImported.

Entry informationi

Entry nameiH8N2K8_RICPO
AccessioniPrimary (citable) accession number: H8N2K8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: July 9, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi