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Protein

D-alanine--D-alanine ligase

Gene

ddlA

Organism
Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) (Myxococcus coralloides)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Mg2+SAAS annotation, Mn2+SAAS annotationNote: Binds 2 magnesium or manganese ions per subunit.SAAS annotation

Pathway: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCCOR1144275:GLBO-3856-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
D-alanine--D-alanine ligaseSAAS annotation (EC:6.3.2.4SAAS annotation)
Gene namesi
Name:ddlAImported
Ordered Locus Names:COCOR_03852Imported
OrganismiCorallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) (Myxococcus coralloides)Imported
Taxonomic identifieri1144275 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeCorallococcus
ProteomesiUP000007587 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotation

Phylogenomic databases

KOiK01921.

Family and domain databases

Gene3Di3.30.1490.20. 2 hits.
3.30.470.20. 3 hits.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 2 hits.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 2 hits.
PROSITEiPS50975. ATP_GRASP. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8MSG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIALTYNLR LSDSEEEAEF DTQETVNTLA GAIERLGHRL ERFEVSGPAS
60 70 80 90 100
RTVARLEAYS PDLIFNTAEG RRGRFREAFY PALFDELGFA YTGSDAYALA
110 120 130 140 150
LTLDKQLTKL ILSKHGIRTP GWQYVEKLSE LQPENLRFPV IVKPNFEGSS
160 170 180 190 200
KGITQDSVAE TLEQVREKVA KALEKYPAGV LVEEYISGRD LTVPFLAAVD
210 220 230 240 250
NDYDGVLAPV EYVIDPEASQ GRKYAIYDYE LKTRREKSVS VRAPANIPAK
260 270 280 290 300
MSEDVRTMAQ KILQVLDCRD LGRLDFRVSD AGVPYFLEIN ALPSLEPGAG
310 320 330 340 350
IYAAAELEGL HLDGVINSII QSAGKRHKIR DNKSRQGRPA RKSGPLRVGF
360 370 380 390 400
SFNVKRVKPS ATAETVQEDS EAEYDSPNTL QAIREAIASW GHEVIDLEAT
410 420 430 440 450
AELPTVLSST PLDIVFNIAE GFKGRNRESQ VPAMLELLDI PYTGSDPATL
460 470 480 490 500
SLALDKALAK KIVRQAGILT PNFQLMVTGK ERLNKEFTTF PLIVKPVAEG
510 520 530 540 550
SSKGVVTKSV CYSEAELRDV VKEIAGKYQQ PALIEEYIGG REFTVGLLGE
560 570 580 590 600
RRPRVLPPME IVFLDKAEKN PVYSFQHKLD WTDRIRYDAP AKIEPALLEK
610 620 630 640 650
LRTAARNSFM ALGCRDVARI DFRMDDKGRI YFIECNPLPG LTPGWSDLVL
660 670 680 690 700
IAAGAGMDYR TLIGEIMAPA IRRYKEREAR RAQTENPAGT QAPPLNKVVQ
710 720
RIEEQNARAN ASAPAENTPA PRPELKS
Length:727
Mass (Da):80,757
Last modified:May 16, 2012 - v1
Checksum:i13AE7F8545CE4238
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003389 Genomic DNA. Translation: AFE08537.1.
RefSeqiWP_014396664.1. NC_017030.1.
YP_005369825.1. NC_017030.1.

Genome annotation databases

EnsemblBacteriaiAFE08537; AFE08537; COCOR_03852.
KEGGiccx:COCOR_03852.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003389 Genomic DNA. Translation: AFE08537.1.
RefSeqiWP_014396664.1. NC_017030.1.
YP_005369825.1. NC_017030.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFE08537; AFE08537; COCOR_03852.
KEGGiccx:COCOR_03852.

Phylogenomic databases

KOiK01921.

Enzyme and pathway databases

UniPathwayiUPA00219.
BioCyciCCOR1144275:GLBO-3856-MONOMER.

Family and domain databases

Gene3Di3.30.1490.20. 2 hits.
3.30.470.20. 3 hits.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 2 hits.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 2 hits.
PROSITEiPS50975. ATP_GRASP. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the fruiting myxobacterium Corallococcus coralloides DSM 2259."
    Huntley S., Zhang Y., Treuner-Lange A., Sensen C.W., Sogaard-Andersen L.
    Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25202 / DSM 2259 / NBRC 100086 / M2Imported.

Entry informationi

Entry nameiH8MSG9_CORCM
AccessioniPrimary (citable) accession number: H8MSG9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: June 24, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.