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H8M0R6

- H8M0R6_SALTM

UniProt

H8M0R6 - H8M0R6_SALTM

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, UMN798_4465
Organism
Salmonella enterica subsp. enterica serovar Typhimurium str. 798
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei546 – 5461 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotations

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciSENT1008297:GLJT-4021-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
ORF Names:UMN798_4465Imported
OrganismiSalmonella enterica subsp. enterica serovar Typhimurium str. 798Imported
Taxonomic identifieri1008297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000007588: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiH8M0R6.

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliH8M0R6.
SMRiH8M0R6. Positions 4-883.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8M0R6-1 [UniParc]FASTAAdd to Basket

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MNEQYSALRS NVSMLGKVLG ETIKDALGEH ILDRVETIRK LSKSSRAGNE    50
ANRQELLTTL QNLSNDELLP VARAFSQFLN LANTAEQYHS ISPKGEAASN 100
PEVIARTLRK LKNQPDLNDA TIKKAVESLS LELVLTAHPT EITRRTLIHK 150
MGEINNCLKQ LDNTDIADYE RHQVMRRLRQ LIAQSWHTDE IRKQRPSPVD 200
EAKWGFAVVE NSLWQGVPNY LRELNEQLEE NLGYKLPVDF VPVRFTSWMG 250
GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDIHVLVSEL SMVDATPELL 300
ALVGEEGASE PYRYLMKKLR ARLMATQSWL EARLKGEKLP KPAGLLTQNE 350
QLWEPLYACY QSLQACGMGI IANGELLDTL RRVKCFGVPL VRIDIRQEST 400
RHTEALGEIT RYLGIGDYES WSEADKQAFL IRELNSKRPL LPRNWEPSND 450
TREVLETCKV IAEAPKGSIA AYVISMAKTP SDVLAVHLLL KEAGIGFAMP 500
VAPLFETLDD LNNADDVMTQ LLNIDWYRGL IQGKQMVMIG YSDSAKDAGV 550
MAASWAQYQA QDALIKTCEK AGIELTLFHG RGGSIGRGGA PAHAALLSQP 600
PGSLKGGLRV TEQGEMIRFK YGLPEVTVSS LSLYTSAILE ANLLPPPEPK 650
DSWRHIMDEL SVISCETYRG YVRENKDFVP YFRSATPEQE LGKLPLGSRP 700
AKRRPTGGVE SLRAIPWIFA WTQNRLMLPA WLGAGTALQK VVEDGKQSEL 750
EAMCRDWPFF STRLGMLEMV FSKADLWLAD YYDQRLVAKT LWPLGKELRD 800
LLEEDIKVVL AIANDSHLMA DLPWIAESIQ LRNVYTDPLN VLQAELLYRS 850
RLTEEQGKSP DPRVEQALMV TIAGVAAGMR NTG 883
Length:883
Mass (Da):99,003
Last modified:May 16, 2012 - v1
Checksum:i2F28CE22308A003E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003386 Genomic DNA. Translation: AFD60942.1.
RefSeqiYP_005399407.1. NC_017046.1.

Genome annotation databases

EnsemblBacteriaiAFD60942; AFD60942; UMN798_4465.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003386 Genomic DNA. Translation: AFD60942.1 .
RefSeqi YP_005399407.1. NC_017046.1.

3D structure databases

ProteinModelPortali H8M0R6.
SMRi H8M0R6. Positions 4-883.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi H8M0R6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFD60942 ; AFD60942 ; UMN798_4465 .

Enzyme and pathway databases

BioCyci SENT1008297:GLJT-4021-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Characterization and Differential Gene Expression between Two Phenotypic Phase Variants in Salmonella enterica Serovar Typhimurium."
    Patterson S.K., Borewicz K., Johnson T., Xu W., Isaacson R.E.
    PLoS ONE 7:E43592-E43592(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 798Imported.

Entry informationi

Entry nameiH8M0R6_SALTM
AccessioniPrimary (citable) accession number: H8M0R6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: September 3, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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