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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

gabT

Organism
Salmonella enterica subsp. enterica serovar Typhimurium str. 798
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciSENT1008297:GLJT-2727-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported
Gene namesi
Name:gabTImported
ORF Names:UMN798_3031Imported
OrganismiSalmonella enterica subsp. enterica serovar Typhimurium str. 798Imported
Taxonomic identifieri1008297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000007588: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiH8LZM1.

Structurei

3D structure databases

ProteinModelPortaliH8LZM1.
SMRiH8LZM1. Positions 2-426.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8LZM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTNNALMQR RHNAVPRGVG QIHPIFAERA ENCRVWDVEG REYLDFAGGI
60 70 80 90 100
AVLNTGHLHP GIVSAVEAQL KKLSHTCFQV LAYEPYLALC ERMNQKVPGD
110 120 130 140 150
FAKKTLLVTT GSEAVENAVK IARAATKRSG AIAFSGAYHG RTHYTLSLTG
160 170 180 190 200
KVHPYSAGMG LMPGHVYRAL YPCPLHNISD DDAIASIERI FKNDAAPEDI
210 220 230 240 250
AAIIIEPVQG EGGFYAASPA FMQRLRALCD QHGIMLIADE VQSGAGRTGT
260 270 280 290 300
LFAMEQMGVA ADITTFAKSI AGGFPLAGVT GRADVMDAIA PGGLGGTYAG
310 320 330 340 350
NPIACAAALA VLDIFEQENL LQKANTLGKT LRDGLMEIAE THREIGDVRG
360 370 380 390 400
LGAMIAIELF ENGDPGKPNA ALTADIVTRA REKGLILLSC GPYYNILRIL
410 420
VPLTIEASQI RQGLEIIAQC FDEAKQA
Length:427
Mass (Da):45,636
Last modified:May 16, 2012 - v1
Checksum:i9B8DD5E7B3B5AC21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003386 Genomic DNA. Translation: AFD59696.1.
RefSeqiYP_005398161.1. NC_017046.1.

Genome annotation databases

EnsemblBacteriaiAFD59696; AFD59696; UMN798_3031.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003386 Genomic DNA. Translation: AFD59696.1.
RefSeqiYP_005398161.1. NC_017046.1.

3D structure databases

ProteinModelPortaliH8LZM1.
SMRiH8LZM1. Positions 2-426.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiH8LZM1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFD59696; AFD59696; UMN798_3031.

Enzyme and pathway databases

BioCyciSENT1008297:GLJT-2727-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Characterization and Differential Gene Expression between Two Phenotypic Phase Variants in Salmonella enterica Serovar Typhimurium."
    Patterson S.K., Borewicz K., Johnson T., Xu W., Isaacson R.E.
    PLoS ONE 7:E43592-E43592(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 798Imported.

Entry informationi

Entry nameiH8LZM1_SALTM
AccessioniPrimary (citable) accession number: H8LZM1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: January 7, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.