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H8LFQ1

- H8LFQ1_STRET

UniProt

H8LFQ1 - H8LFQ1_STRET

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus pneumoniae (strain ST556)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (16 May 2012)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei124 – 1241UniRule annotation
    Active sitei547 – 5471UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciSPNE1130804:GLLC-1119-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    Ordered Locus Names:MYY_1115Imported
    OrganismiStreptococcus pneumoniae (strain ST556)Imported
    Taxonomic identifieri1130804 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000005235: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.
    OMAiELSTISC.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H8LFQ1-1 [UniParc]FASTAAdd to Basket

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    MQEEVLILTE LLEDITKNML APETFEKIIQ LKELSTQEDY QGLNRLVTSL    50
    SNDEMVYISR YFSILPLLIN ISEDVDLAYE INHQNNIDQD YLGKLSTTIK 100
    LVAEKENAVE ILEHLNVVPV LTAHPTQVQR KSMLDLTNHI HSLLRKYRDV 150
    KLGLINKDKW YNDLRRYIEI IMQTDMIREK KLKVTNEITN AMEYYNSSFL 200
    KAVPHLTTEY KRLAQAHGLN LKQAKPITMG MWIGGDRDGN PFVTAKTLKQ 250
    SALTQCEVIM NYYDKKIYQL YREFSLSTSI VNVSKQVREM ARQSKDNSIY 300
    REKELYRRAL FDIQSKIQAT KTYLIEDEEV GTRYETANDF YKDLIAIRDS 350
    LLENKGESLI SGDFVELLQA VEIFGFYLAS IDMRQDSSVY EACVAELLKS 400
    AGIHSRYSEL SEEEKCDLLL KELEEDPRIL SATHAEKSEL LAKELAIFKT 450
    ARVLKDKLGD DVIRQTIISH ATSLSDMLEL AILLKEVGLV DTERARVQIV 500
    PLFETIEDLD HSEETMRKYL SLSLAKKWID SRNNYQEIML GYSDSNKDGG 550
    YLSSCWTLYK AQQQLTAIGD EFGVKVTFFH GRGGTVGRGG GPTYEAITSQ 600
    PLKSIKDRIR LTEQGEVIGN KYGNKDAAYY NLEMLVSAAI NRMITHKKSD 650
    TNTPNRYEAI MDQVVDRSYD VYRDLVFGNE HFYDYFFESS PIKAISSFNI 700
    GSRPAARKTI TEIGGLRAIP WVFSWSQSRV MFPGWYGVGS SFKEFINKNP 750
    ENIAILRDMY QNWPFFQSLL SNVDMVLSKS NMNIAFEYAK LCEDEQVKAI 800
    YETILNEWQV TKNVILAIEG HDELLADNPY LKASLDYRMP YFNILNYIQL 850
    ELIKRQRRGE LSSDQERLIH ITINGIATGL RNSG 884
    Length:884
    Mass (Da):101,689
    Last modified:May 16, 2012 - v1
    Checksum:iF3F67F57E65167A7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003357 Genomic DNA. Translation: AFC94773.1.
    RefSeqiWP_001154825.1. NC_017769.1.
    YP_006253308.1. NC_017769.1.

    Genome annotation databases

    EnsemblBacteriaiAFC94773; AFC94773; MYY_1115.
    GeneIDi12901456.
    KEGGisnd:MYY_1115.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003357 Genomic DNA. Translation: AFC94773.1 .
    RefSeqi WP_001154825.1. NC_017769.1.
    YP_006253308.1. NC_017769.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFC94773 ; AFC94773 ; MYY_1115 .
    GeneIDi 12901456.
    KEGGi snd:MYY_1115.

    Phylogenomic databases

    KOi K01595.
    OMAi ELSTISC.

    Enzyme and pathway databases

    BioCyci SPNE1130804:GLLC-1119-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Streptococcus pneumoniae strain ST556, a multidrug-resistant isolate from an otitis media patient."
      Li G., Hu F.Z., Yang X., Cui Y., Yang J., Qu F., Gao G.F., Zhang J.R.
      J. Bacteriol. 194:3294-3295(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ST556Imported.

    Entry informationi

    Entry nameiH8LFQ1_STRET
    AccessioniPrimary (citable) accession number: H8LFQ1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 16, 2012
    Last sequence update: May 16, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3