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H8LEY3

- H8LEY3_ENTFU

UniProt

H8LEY3 - H8LEY3_ENTFU

Protein

Elongation factor Tu

Gene

tuf_1

Organism
Enterococcus faecium (strain Aus0004)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (16 May 2012)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciEFAE1155766:GLCU-1241-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tuf_1Imported
    Synonyms:tufUniRule annotation
    Ordered Locus Names:EFAU004_01233Imported
    OrganismiEnterococcus faecium (strain Aus0004)Imported
    Taxonomic identifieri1155766 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
    ProteomesiUP000007591: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliH8LEY3.
    SMRiH8LEY3. Positions 2-393.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    KOiK02358.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H8LEY3-1 [UniParc]FASTAAdd to Basket

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    MAKEHYDRSK PHVNIGTIGH VDHGKTTLTA AITTVLGKKG LANPQDYASI    50
    DAAPEERERG ITINTAHVEY ETEKRHYAHI DAPGHADYVK NMITGAAQMD 100
    GAILVVSATD GPMPQTREHI LLSRQVGVKY LIVFLNKVDL VDDEELIDLV 150
    EMEVRELLSE YGFPGDDTPV IKGSALKALQ GDPDAEAAIM ELMDTVDEYI 200
    PTPERDTDKP LLLPVEDVFS ITGRGTVASG RIDRGAVRVG DEVEIVGIKP 250
    ETQKAVVTGV EMFRKTLDYG EAGDNVGVLL RGIQRDDIER GQVLAKPGSI 300
    TPHTKFKAEV YVLTKEEGGR HTPFFNNYRP QFYFRTTDVT GTITLPEDTE 350
    MVMPGDNVTI DVDLIHPIAV ENGTTFSIRE GGRTVGSGIV TEIEA 395
    Length:395
    Mass (Da):43,217
    Last modified:May 16, 2012 - v1
    Checksum:i2C095B1FC458397B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003351 Genomic DNA. Translation: AFC63318.1.
    RefSeqiYP_005354436.1. NC_017022.1.

    Genome annotation databases

    EnsemblBacteriaiAFC63318; AFC63318; EFAU004_01233.
    GeneIDi11956888.
    KEGGiefc:EFAU004_01233.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003351 Genomic DNA. Translation: AFC63318.1 .
    RefSeqi YP_005354436.1. NC_017022.1.

    3D structure databases

    ProteinModelPortali H8LEY3.
    SMRi H8LEY3. Positions 2-393.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFC63318 ; AFC63318 ; EFAU004_01233 .
    GeneIDi 11956888.
    KEGGi efc:EFAU004_01233.

    Phylogenomic databases

    KOi K02358.

    Enzyme and pathway databases

    BioCyci EFAE1155766:GLCU-1241-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Aus0004Imported.

    Entry informationi

    Entry nameiH8LEY3_ENTFU
    AccessioniPrimary (citable) accession number: H8LEY3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 16, 2012
    Last sequence update: May 16, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3