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H8LEY3 (H8LEY3_ENTFU) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Elongation factor Tu HAMAP-Rule MF_00118

Short name=EF-Tu HAMAP-Rule MF_00118
Gene names
Name:tuf_1 EMBL AFC63318.1
Synonyms:tuf HAMAP-Rule MF_00118
Ordered Locus Names:EFAU004_01233 EMBL AFC63318.1
OrganismEnterococcus faecium (strain Aus0004) [Complete proteome] [HAMAP] EMBL AFC63318.1
Taxonomic identifier1155766 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325 HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325 HAMAP-Rule MF_00118

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding19 – 268GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding81 – 855GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding136 – 1394GTP By similarity HAMAP-Rule MF_00118

Sequences

Sequence LengthMass (Da)Tools
H8LEY3 [UniParc].

Last modified May 16, 2012. Version 1.
Checksum: 2C095B1FC458397B

FASTA39543,217
        10         20         30         40         50         60 
MAKEHYDRSK PHVNIGTIGH VDHGKTTLTA AITTVLGKKG LANPQDYASI DAAPEERERG 

        70         80         90        100        110        120 
ITINTAHVEY ETEKRHYAHI DAPGHADYVK NMITGAAQMD GAILVVSATD GPMPQTREHI 

       130        140        150        160        170        180 
LLSRQVGVKY LIVFLNKVDL VDDEELIDLV EMEVRELLSE YGFPGDDTPV IKGSALKALQ 

       190        200        210        220        230        240 
GDPDAEAAIM ELMDTVDEYI PTPERDTDKP LLLPVEDVFS ITGRGTVASG RIDRGAVRVG 

       250        260        270        280        290        300 
DEVEIVGIKP ETQKAVVTGV EMFRKTLDYG EAGDNVGVLL RGIQRDDIER GQVLAKPGSI 

       310        320        330        340        350        360 
TPHTKFKAEV YVLTKEEGGR HTPFFNNYRP QFYFRTTDVT GTITLPEDTE MVMPGDNVTI 

       370        380        390 
DVDLIHPIAV ENGTTFSIRE GGRTVGSGIV TEIEA 

« Hide

References

[1]"Comparative Analysis of the First Complete Enterococcus faecium Genome."
Lam M.M., Seemann T., Bulach D.M., Gladman S.L., Chen H., Haring V., Moore R.J., Ballard S., Grayson M.L., Johnson P.D., Howden B.P., Stinear T.P.
J. Bacteriol. 194:2334-2341(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Aus0004 EMBL AFC63318.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003351 Genomic DNA. Translation: AFC63318.1.
RefSeqYP_005354436.1. NC_017022.1.

3D structure databases

ProteinModelPortalH8LEY3.
SMRH8LEY3. Positions 2-393.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFC63318; AFC63318; EFAU004_01233.
GeneID11956888.
KEGGefc:EFAU004_01233.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK02358.

Enzyme and pathway databases

BioCycEFAE1155766:GLCU-1241-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH8LEY3_ENTFU
AccessionPrimary (citable) accession number: H8LEY3
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: June 11, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)