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H8L9K2 (H8L9K2_ENTFU) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length194 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. SAAS SAAS020633 HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity SAAS SAAS020633 HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165 HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding85 – 884ATP By similarity HAMAP-Rule MF_00124

Sites

Active site861Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1431Zinc By similarity HAMAP-Rule MF_00124
Metal binding1461Zinc By similarity HAMAP-Rule MF_00124
Metal binding1801Zinc By similarity HAMAP-Rule MF_00124
Metal binding1831Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
H8L9K2 [UniParc].

Last modified May 16, 2012. Version 1.
Checksum: AFED9871CB7F4735

FASTA19422,347
        10         20         30         40         50         60 
MAQLFFKYGA MNSGKTIEIL KVAHNYEEQN KPVVLMTSGI DTRDGLGVVS SRIGLKRNAM 

        70         80         90        100        110        120 
PIFEETDVFD VIQKMESKPY CVLIDEAQFL KKKHVIAFTR IVDELDIPVM AFGLKNDFRN 

       130        140        150        160        170        180 
ELFEGSKYLL LYADKIEEMK TICWFCHKKA IMNLHYIDGN PVYEGDQVQI GGNEAYYPVC 

       190 
RKHYFHPSMI TEGE 

« Hide

References

[1]"Comparative Analysis of the First Complete Enterococcus faecium Genome."
Lam M.M., Seemann T., Bulach D.M., Gladman S.L., Chen H., Haring V., Moore R.J., Ballard S., Grayson M.L., Johnson P.D., Howden B.P., Stinear T.P.
J. Bacteriol. 194:2334-2341(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Aus0004 EMBL AFC64387.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003351 Genomic DNA. Translation: AFC64387.1.
RefSeqYP_005355505.1. NC_017022.1.

3D structure databases

ProteinModelPortalH8L9K2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFC64387; AFC64387; EFAU004_02304.
GeneID11955689.
KEGGefc:EFAU004_02304.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.

Enzyme and pathway databases

BioCycEFAE1155766:GLCU-2343-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH8L9K2_ENTFU
AccessionPrimary (citable) accession number: H8L9K2
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: April 16, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)