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H8L8W1 (H8L8W1_ENTFU) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HAMAP-Rule MF_01039

Short name=BPG-dependent PGAM HAMAP-Rule MF_01039
Short name=PGAM HAMAP-Rule MF_01039
Short name=Phosphoglyceromutase HAMAP-Rule MF_01039
Short name=dPGM HAMAP-Rule MF_01039
EC=5.4.2.11 HAMAP-Rule MF_01039
Gene names
Name:gpmA HAMAP-Rule MF_01039
Ordered Locus Names:EFAU004_01564 EMBL AFC63648.1
OrganismEnterococcus faecium (strain Aus0004) [Complete proteome] [HAMAP] EMBL AFC63648.1
Taxonomic identifier1155766 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

Protein attributes

Sequence length222 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. RuleBase RU004512 HAMAP-Rule MF_01039

Catalytic activity

2-phospho-D-glycerate = 3-phospho-D-glycerate. RuleBase RU004512 HAMAP-Rule MF_01039 SAAS SAAS001345

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. RuleBase RU004512 HAMAP-Rule MF_01039

Sequence similarities

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. HAMAP-Rule MF_01039

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region20 – 2122-phospho-D-glycerate binding By similarity HAMAP-Rule MF_01039
Region86 – 8942-phospho-D-glycerate binding By similarity HAMAP-Rule MF_01039
Region113 – 11422-phospho-D-glycerate binding By similarity HAMAP-Rule MF_01039

Sites

Active site81Tele-phosphohistidine intermediate By similarity HAMAP-Rule MF_01039
Active site1761 By similarity HAMAP-Rule MF_01039
Binding site1412-phospho-D-glycerate By similarity HAMAP-Rule MF_01039
Binding site5912-phospho-D-glycerate By similarity HAMAP-Rule MF_01039
Binding site9712-phospho-D-glycerate By similarity HAMAP-Rule MF_01039
Binding site17812-phospho-D-glycerate By similarity HAMAP-Rule MF_01039

Sequences

Sequence LengthMass (Da)Tools
H8L8W1 [UniParc].

Last modified May 16, 2012. Version 1.
Checksum: 3A016FAFC147659A

FASTA22225,637
        10         20         30         40         50         60 
MKLVLLRHGE SEANFENYWT GWLDVALTEK GKEQAAVAGQ KMLEAGLQFD AVYTSVLKRA 

        70         80         90        100        110        120 
ILTGQVALEE MGQLWLPIIK TWRLNERHYG DLVGKNKDKM KEIYGKDQVK TWRRGYTEVP 

       130        140        150        160        170        180 
PLTAENRFDR RYDHLDPHLI PYGESLEMTV NRIIPLWQDH LAPKLKDRQD LLVVGHGNSI 

       190        200        210        220 
RALTKYLEDV PEDQMDTIDI PNAQPIQYTL ADDLTILDKK IL 

« Hide

References

[1]"Comparative Analysis of the First Complete Enterococcus faecium Genome."
Lam M.M., Seemann T., Bulach D.M., Gladman S.L., Chen H., Haring V., Moore R.J., Ballard S., Grayson M.L., Johnson P.D., Howden B.P., Stinear T.P.
J. Bacteriol. 194:2334-2341(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Aus0004 EMBL AFC63648.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003351 Genomic DNA. Translation: AFC63648.1.
RefSeqYP_005354766.1. NC_017022.1.

3D structure databases

ProteinModelPortalH8L8W1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFC63648; AFC63648; EFAU004_01564.
GeneID11954937.
KEGGefc:EFAU004_01564.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01834.

Enzyme and pathway databases

BioCycEFAE1155766:GLCU-1591-MONOMER.
UniPathwayUPA00109; UER00186.

Family and domain databases

Gene3D3.40.50.1240. 1 hit.
HAMAPMF_01039. PGAM_GpmA.
InterProIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERPTHR11931. PTHR11931. 1 hit.
PfamPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMSSF53254. SSF53254. 1 hit.
TIGRFAMsTIGR01258. pgm_1. 1 hit.
PROSITEPS00175. PG_MUTASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH8L8W1_ENTFU
AccessionPrimary (citable) accession number: H8L8W1
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: June 11, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)