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Protein
Submitted name:

Isocitrate dehydrogenase

Gene

MCC_02560

Organism
Rickettsia rhipicephali (strain 3-7-female6-CWPP)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: InterPro
  2. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciRRHI1105113:GLJK-429-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:MCC_02560Imported
OrganismiRickettsia rhipicephali (strain 3-7-female6-CWPP)Imported
Taxonomic identifieri1105113 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008006 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8KJM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEFTPITIA YGDGIGPEIM EAVLYILRKA EARIRLETIE VGAKLYKKHY
60 70 80 90 100
TSGISEESWE SIQRTGIILK APITTPQGGG YKSLNVTIRK TLQLFANIRP
110 120 130 140 150
SVSFHPFTRT LYPNLNLTII RENEEDLYAG IEYRQTHNMY ESMKLISHTG
160 170 180 190 200
CEKIIRYAFE YAVKNNRKKV TCLSKDNIMK FSDGVLHKVF NEIAKEYPQI
210 220 230 240 250
NNAHYIIDIG TARLATKPEI FDVIVTSNLY GDIISDVAAE ISGSVGLAGS
260 270 280 290 300
ANIGQHYAMF EAVHGSAPDI AGKDIANPSG LLNAAIMMLV HIGQGDIATL
310 320 330 340 350
IENAWKKTIE DGVHTADIYN EQSSSKKVGT KEFAEEVTKR LGQLPTKLPK
360 370 380 390 400
AAYPLIAEKQ ESNIDYKIDT KEVKQLVGTD IFVNMNVSSA HDIADKINKL
410 420 430 440 450
DLGNFELKTI SSKGLKLWPR DTRFETVSDH WCCRFMNKDG TEIKHLDITR
460 470 480
LLEALSTANI DFIKVENLFE FDGVAGYSLA QGE
Length:483
Mass (Da):53,880
Last modified:May 16, 2012 - v1
Checksum:i8BF01259A0260653
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003342 Genomic DNA. Translation: AFC72129.1.
RefSeqiWP_014408373.1. NC_017042.1.
YP_005390202.1. NC_017042.1.

Genome annotation databases

EnsemblBacteriaiAFC72129; AFC72129; MCC_02560.
KEGGirre:MCC_02560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003342 Genomic DNA. Translation: AFC72129.1.
RefSeqiWP_014408373.1. NC_017042.1.
YP_005390202.1. NC_017042.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFC72129; AFC72129; MCC_02560.
KEGGirre:MCC_02560.

Phylogenomic databases

KOiK00031.

Enzyme and pathway databases

BioCyciRRHI1105113:GLJK-429-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Rickettsia rhipicephali strain 3-7-female6-CWPP."
    Johnson S.L., Munk A.C., Han S., Bruce D.C., Dasch G.A.
    Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 3-7-female6-CWPPImported.

Entry informationi

Entry nameiH8KJM6_RICR3
AccessioniPrimary (citable) accession number: H8KJM6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: April 1, 2015
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.