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H8JW16 (H8JW16_VIBCL) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length192 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. SAAS SAAS020634 HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity SAAS SAAS020634 HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165 HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding87 – 904ATP By similarity HAMAP-Rule MF_00124

Sites

Active site881Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1451Zinc By similarity HAMAP-Rule MF_00124
Metal binding1471Zinc By similarity HAMAP-Rule MF_00124
Metal binding1821Zinc By similarity HAMAP-Rule MF_00124
Metal binding1851Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
H8JW16 [UniParc].

Last modified May 16, 2012. Version 1.
Checksum: B2532D1C6CBA9E8F

FASTA19221,659
        10         20         30         40         50         60 
MAQMYFYYSA MNAGKSTTLL QSAFNYQERG MNPLIFTAAI DDRFGVGKVS SRIGLEAEAH 

        70         80         90        100        110        120 
LFHADTDLLH VIATLHEAEP RHCILMDECQ FLSKEQVYQL TEVVDKLDIP VLCYGLRTDF 

       130        140        150        160        170        180 
LGELFEGSKY LLSWADKLIE LKTICHCGRK ANMVIRTDEH GNAISEGDQV AIGGNDKYVS 

       190 
VCRQHYKEAL GR 

« Hide

References

[1]"Complete Genome Sequence of a Sucrose-Nonfermenting Epidemic Strain of Vibrio cholerae O1 from Brazil."
Morais L.L., Garza D.R., Loureiro E.C., Nunes K.N., Vellasco R.S., da Silva C.P., Nunes M.R., Thompson C.C., Vicente A.C., Santos E.C.
J. Bacteriol. 194:2772-2772(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: IEC224 EMBL AFC57969.1.
[2]"Genome-Wide Study of the Defective Sucrose Fermenter Strain of Vibrio cholerae from the Latin American Cholera Epidemic."
Garza D.R., Thompson C.C., Loureiro E.C., Dutilh B.E., Inada D.T., Junior E.C., Cardoso J.F., Nunes M.R., de Lima C.P., Silvestre R.V., Nunes K.N., Santos E.C., Edwards R.A., Vicente A.C., de Sa Morais L.L.
PLoS ONE 7:E37283-E37283(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: IEC224 EMBL AFC57969.1.
[3]Garza D.R.Jr., Thompson C.C., Loureiro E.C.B., Dutilh B.E., Inada D.T., Junior E.C.S., Cardoso J.F., Nunes M.R.T., de Lima C.P.S., Vellasco R.S., Nunes K.N.B., Santos E.C.O., Edwards R.A., Vicente A.C.P., Morais L.L.C.S.
Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: IEC224 EMBL AFC57969.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003330 Genomic DNA. Translation: AFC57969.1.
RefSeqYP_005332957.1. NC_016944.1.

3D structure databases

ProteinModelPortalH8JW16.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFC57969; AFC57969; O3Y_05445.
GeneID11914085.
KEGGvci:O3Y_05445.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.

Enzyme and pathway databases

BioCycVCHO1134456:GLMN-1150-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH8JW16_VIBCL
AccessionPrimary (citable) accession number: H8JW16
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: June 11, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)