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H8JH56

- H8JH56_MYCIT

UniProt

H8JH56 - H8JH56_MYCIT

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Mycobacterium intracellulare MOTT-64
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641UniRule annotation
Active sitei596 – 5961UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:OCQ_32980Imported
OrganismiMycobacterium intracellulare MOTT-64Imported
Taxonomic identifieri1138383 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
ProteomesiUP000008003: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8JH56-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MADASEAPED TLEPIGAVQR TPVGRAATEP MRADIRLLGA ILGDTVREQN
60 70 80 90 100
GREVFELVER ARVESFRVRR SEIDRAELAR MFYRIDIHQA IPVIRAFSHF
110 120 130 140 150
ALLANVAEDI HRERRRAVHV AAGEPPPDST LAATYAKLDE AQLDSDTVAD
160 170 180 190 200
ALKGAVVAPV ITAHPTETRR RTVFVTQHRI NELMRLHAEG HAETDDGRNI
210 220 230 240 250
ELELRRQVLT LWQTALIRLS RLQITDEIEV GLRYYAAAFF KVIPQVNAEV
260 270 280 290 300
RDTLRARWPD ADLFDEPMLQ PGSWIGGDRD GNPNVTADVV RQATGSAAFT
310 320 330 340 350
ALAHYLAELT ALEQELSMSA RLVSVTPALT ELAGGCAEKA RADEPYRRAV
360 370 380 390 400
RVIRARLSAT SAAILDRTPQ QVLDLGLPPY ETPAELGADL DTMDESLRGH
410 420 430 440 450
GSALLADDRL ALLREGVRVF GFHLCGLDMR QNSDAHEEVI CELLAWAGVH
460 470 480 490 500
PDYRSLPEDE RVELLAAELG TRRPLVADDA QLSDLARGEL DVVRAAAHAI
510 520 530 540 550
KRYGPSAVPN YVISMCRSVS DVLEAAILLK EAGLIDASGP EPYCPVGISP
560 570 580 590 600
LFETIDDLHN GATILHAMLE LPIYRALVAA RGETQEVMLG YSDSNKDGGY
610 620 630 640 650
LASSWAVYRA ELALVEVARK TGIRLRLFHG RGGTVGRGGG PSYEAILAQP
660 670 680 690 700
PGAVNGSLRL TEQGEVIAAK YAEPRVAQRN LESLLAATLE STLLDVEGLG
710 720 730 740 750
DAAEPAYAVL DEVAVLAQRA YAELVHDTPG FVDYFMASTP VSEIGSLNIG
760 770 780 790 800
SRPTSRKPTE SISDLRAIPW VLAWSQSRVM LPGWYGTGSA FEQWIAAGPQ
810 820 830 840 850
SEAERVSILH DLYQRWPFFR SVLSNLAQVL AKSDLGLAAR YAELVDDEEL
860 870 880 890 900
RRRVFGKIVD EHGRTIAMHK LITGQDNLLA DNPALARSVF NRFPYLEPLN
910 920 930
HLQVELLRRY RSGDDDELVQ RGILLTMNGL ASALRNSG
Length:938
Mass (Da):102,939
Last modified:May 16, 2012 - v1
Checksum:i4D31A43F0F08C903
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003324 Genomic DNA. Translation: AFC54810.1.
RefSeqiYP_005349131.1. NC_016948.1.

Genome annotation databases

EnsemblBacteriaiAFC54810; AFC54810; OCQ_32980.
GeneIDi11899542.
KEGGimir:OCQ_32980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003324 Genomic DNA. Translation: AFC54810.1 .
RefSeqi YP_005349131.1. NC_016948.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFC54810 ; AFC54810 ; OCQ_32980 .
GeneIDi 11899542.
KEGGi mir:OCQ_32980.

Phylogenomic databases

KOi K01595.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Mycobacterium intracellulare Clinical Strain MOTT-64, Belonging to the INT1 Genotype."
    Kim B.J., Choi B.S., Lim J.S., Choi I.Y., Kook Y.H., Kim B.J.
    J. Bacteriol. 194:3268-3268(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MOTT-64Imported.

Entry informationi

Entry nameiH8JH56_MYCIT
AccessioniPrimary (citable) accession number: H8JH56
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: November 26, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3