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H8J339

- H8J339_MYCIT

UniProt

H8J339 - H8J339_MYCIT

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Protein

Phosphoenolpyruvate carboxylase

Gene
ppc, OCO_31900
Organism
Mycobacterium intracellulare MOTT-02
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641 By similarityUniRule annotation
Active sitei596 – 5961 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciMINT1138382:GLGO-3225-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:OCO_31900Imported
OrganismiMycobacterium intracellulare MOTT-02Imported
Taxonomic identifieri1138382 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
ProteomesiUP000008002: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8J339-1 [UniParc]FASTAAdd to Basket

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MADASEAPED TLEPIGAVQR TPVGREATEP MRADIRLLGA ILGDTVREQN    50
GREVFELVER ARVESFRVRR SEIDRAELAR MFFRIDIHQA IPVIRAFSHF 100
ALLANVAEDI HRERRRAVHV AAGEPPPDST LAATYAKLDE AQLDSDTVAD 150
ALKGAVVAPV ITAHPTETRR RTVFVTQHRI TELMRLHAEG HAETDDGRNI 200
ELELRRQVLT LWQTALIRLS RLQITDEIEV GLRYYAAAFF KVIPQVNAEV 250
RDALRARWPD ADLFDEPMLQ PGSWIGGDRD GNPNVTADVV RQATGSAAFT 300
ALAHYLAELT ALEQELSMSA RLVSVTPALT ELAGGCAEKA RADEPYRRAV 350
RVIRARLSAT SAAILDRTPQ QVLDLGLPPY ETPAELGADL DTIDESLRGH 400
GSALLADDRL ALLREGVRVF GFHLCGLDMR QNSDAHEEVI CELLAWAGVH 450
PDYRSLPEDE RVELLAAELG TRRPLVADDA QLSDLARGEL GVVRAAAHAI 500
KRYGPSAVPN YVISMCRSVS DVLEAAILLK EAGLIDASGP EPYCPVGISP 550
LFETIDDLHN GATILHAILE LPIYRALVAA RGETQEVMLG YSDSNKDGGY 600
LASSWAVYRA ELALVEVARK TGIRLRLFHG RGGTVGRGGG PSYEAILAQP 650
PGAVNGSLRL TEQGEVIAAK YAEPQAAQRN LESLLAATLE STLLDVEGLG 700
DAAEPAYAVL DEVAVLAQRA YAELVHDTPG FVDYFMASTP VSEIGSLNIG 750
SRPTSRKPTE SISDLRAIPW VLAWSQSRVM LPGWYGTGSA FEQWIAAGPQ 800
SEAERVSILH DLYQRWPFFR SVLSNLAQVL AKSDLGLAAR YAELVDDEEL 850
RRRVFDKIVD EHGRTIAMHK LITGQDNLLA DNPALARSVF NRFPYLEPLN 900
HLQVELLRRY RSGDDDELVQ RGILLTMNGL ASALRNSG 938
Length:938
Mass (Da):102,846
Last modified:May 16, 2012 - v1
Checksum:i5BA3EAF6CEDCF0C6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003323 Genomic DNA. Translation: AFC49553.1.
RefSeqiYP_005343874.1. NC_016947.1.

Genome annotation databases

EnsemblBacteriaiAFC49553; AFC49553; OCO_31900.
GeneIDi11904732.
KEGGimit:OCO_31900.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003323 Genomic DNA. Translation: AFC49553.1 .
RefSeqi YP_005343874.1. NC_016947.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFC49553 ; AFC49553 ; OCO_31900 .
GeneIDi 11904732.
KEGGi mit:OCO_31900.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci MINT1138382:GLGO-3225-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Mycobacterium intracellulare Clinical Strain MOTT-02."
    Kim B.J., Choi B.S., Lim J.S., Choi I.Y., Lee J.H., Chun J., Kook Y.H., Kim B.J.
    J. Bacteriol. 194:2771-2771(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MOTT-02Imported.

Entry informationi

Entry nameiH8J339_MYCIT
AccessioniPrimary (citable) accession number: H8J339
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: September 3, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi