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H8IQQ0 (H8IQQ0_MYCIA) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length420 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 SAAS SAAS009006 HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. SAAS SAAS009006 HAMAP-Rule MF_01201

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site761Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site3051Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1741Substrate By similarity HAMAP-Rule MF_01201
Binding site3531Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue761N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
H8IQQ0 [UniParc].

Last modified May 16, 2012. Version 1.
Checksum: 0E5E87B2D553D341

FASTA42044,587
        10         20         30         40         50         60 
MELLRRSRRN LANKSTLGGV RRGSGTMAPM TGRAATPISL TPGLLAEALV DLGAIAHNVR 

        70         80         90        100        110        120 
LLCEQAGGAQ VMAVVKADGY GHGAAQTARA ALAAGAAELG VATVDEALAL RADGVRAPVL 

       130        140        150        160        170        180 
AWLHPPGFDF GPALLADVQI AVSSERQLDE LLDAVRRTGR TATVTVKVDT GLNRNGVPPE 

       190        200        210        220        230        240 
HYPSMLTALR RAVAENAIVL RGLMSHMVYA DQPANPVNDL QAQRFTEMLA QARDQGVRYE 

       250        260        270        280        290        300 
AAHLSNSSAT MSRPDLAFDM VRPGIAVYGL SPVPERGDMG LIPAMTVKCP VALVKSIRAG 

       310        320        330        340        350        360 
ESVSYGHTWT ARRDTTLALL PVGYADGVFR SLGNRLEVLI NGRRRPGVGR ICMDQFVVDL 

       370        380        390        400        410        420 
GPGPTDVAEG DEAILFGPGA SGEPTAQDWA DLLGTIHYEV VTSPRGRITR TYREARTIEP 

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References

[1]"Complete genome sequence of Mycobacterium intracellulare strain ATCC 13950T."
Kim B.J., Choi B.S., Lim J.S., Choi I.Y., Lee J.H., Chun J., Kook Y.H., Kim B.J.
J. Bacteriol. 194:2750-2750(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13950 / DSM 43223 / JCM 6384 / NCTC 13025 / 3600.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003322 Genomic DNA. Translation: AFC45456.1.
RefSeqYP_005339777.1. NC_016946.1.

3D structure databases

ProteinModelPortalH8IQQ0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFC45456; AFC45456; OCU_42370.
GeneID11910992.
KEGGmia:OCU_42370.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycMINT487521:GLGN-4280-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH8IQQ0_MYCIA
AccessionPrimary (citable) accession number: H8IQQ0
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: February 19, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)