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H8IGR3 (H8IGR3_PASMH) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. SAAS SAAS020622 HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. RuleBase RU004188 HAMAP-Rule MF_01201

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site361Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2561Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1321Substrate By similarity HAMAP-Rule MF_01201
Binding site3041Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue361N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
H8IGR3 [UniParc].

Last modified May 16, 2012. Version 1.
Checksum: BCA442DA317F3BA7

FASTA36039,483
        10         20         30         40         50         60 
MNMKPATAKI SSVALKHNIQ TIKQKAPQSK IIAVVKANAY GHGVVFVSAA VEELVDCFGV 

        70         80         90        100        110        120 
ARLEEALSLR SNGITKPILL LEGFFCDKDL PVIAINNIQT VVHNVEQLAA LKAAKVPNPI 

       130        140        150        160        170        180 
KVWLKIDTGM HRLGVALEDV EYFYQALRDS ENVDPQIGFV SHFSRADELE CDYTKLQLTR 

       190        200        210        220        230        240 
FLNATQNKAG EKSIAASGGI LFWENSHLDW IRPGIIMYGI SPINVPAQEY DLTPVMTLTS 

       250        260        270        280        290        300 
SLIAIKQHKK GEPVGYGGIW VSDKDTKIGV VAIGYGDGYP RDIPTGTPVY LNGRRVPIVG 

       310        320        330        340        350        360 
RVSMDMLTVD LGAEAQDKVG DEVILWGKEL PIEEIADISG VISYELITKL TPRVLTEYID 

« Hide

References

[1]"Complete genome sequence of Pasteurella multocida HN06, a toxigenic strain of serogroup D."
Liu W., Xu Z., Liang W., Wu B.
Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HN06.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003313 Genomic DNA. Translation: AFF23687.1.
RefSeqYP_005362858.1. NC_017027.1.

3D structure databases

ProteinModelPortalH8IGR3.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFF23687; AFF23687; PMCN06_0432.
GeneID11961877.
KEGGpmv:PMCN06_0432.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycPMUL1132496:GLIB-450-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH8IGR3_PASMH
AccessionPrimary (citable) accession number: H8IGR3
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: July 9, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)