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Protein

Thymidine kinase

Gene

tdk

Organism
Pasteurella multocida (strain HN06)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMUL1132496:GLIB-2280-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkImported
Ordered Locus Names:PMCN06_2227Imported
OrganismiPasteurella multocida (strain HN06)Imported
Taxonomic identifieri1132496 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaePasteurella
ProteomesiUP000007889: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8IDA9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNTLVYTAAI DDRFGVGKVT SRIGISQEAQ LFHKESDLFV EIAQHLQQQP
60 70 80 90 100
LHCILVDEAQ FLTKTQVYQL SEVVDKLKVP VLCYGLRTDF QAELFEGSKY
110 120 130 140 150
LLAWADQLEE LKTICYCGRK ANFVLRLNEK GDVVRDGAQI QIGGNDSYLS
160
VCRLHYKEKI AL
Length:162
Mass (Da):18,415
Last modified:May 16, 2012 - v1
Checksum:i1BF403C8100FFA1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003313 Genomic DNA. Translation: AFF25448.1.
RefSeqiWP_015691135.1. NC_017027.1.
YP_005364619.1. NC_017027.1.

Genome annotation databases

EnsemblBacteriaiAFF25448; AFF25448; PMCN06_2227.
GeneIDi11961362.
KEGGipmv:PMCN06_2227.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003313 Genomic DNA. Translation: AFF25448.1.
RefSeqiWP_015691135.1. NC_017027.1.
YP_005364619.1. NC_017027.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFF25448; AFF25448; PMCN06_2227.
GeneIDi11961362.
KEGGipmv:PMCN06_2227.

Phylogenomic databases

KOiK00857.

Enzyme and pathway databases

BioCyciPMUL1132496:GLIB-2280-MONOMER.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Pasteurella multocida HN06, a toxigenic strain of serogroup D."
    Liu W., Xu Z., Liang W., Wu B.
    Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HN06Imported.

Entry informationi

Entry nameiH8IDA9_PASMH
AccessioniPrimary (citable) accession number: H8IDA9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: February 4, 2015
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.