H8I0H1 (H8I0H1_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase EMBL AFE14550.1

Gene names

ORF Names:

MRGA423_21620 EMBL AFE14550.1

Organism

Mycobacterium tuberculosis RGTB423 EMBL AFE14550.1

Taxonomic identifier

1091501 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › Mycobacterium tuberculosis

Protein attributes

Sequence length	460 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H8I0H1 [UniParc]. Last modified May 16, 2012. Version 1. Checksum: 2E015CE0093BC48F	FASTA	460	50,768
	10 20 30 40 50 60 MSRSHPSVPA HSIAPAYTGR MFTAPVPALR MPDESMDPEA AYRFIHDELM LDGSSRLNLA 70 80 90 100 110 120 TFVTTWMDPE AEKLMAETFD KNMIDKDEYP ATAAIEARCV SMVADLFHAE GLRDHDPTSA 130 140 150 160 170 180 TGVSTIGSSE AVMLGGLALK WRWRQRVGSW KGRMPNLVMG SNVQVVWEKF CRYFDVEPRY 190 200 210 220 230 240 LPMERGRYVI TPEQVLAAVD ENTIGVVAIL GTTYTGELEP IAETCAALDK LAAGGGVDVP 250 260 270 280 290 300 VHVDAASGGF VVPFLHPDLV WDFRLPRVVS INVSGHKYGL TYPGVGFVVW RGPEHLPEDL 310 320 330 340 350 360 VFRVNYLGGD MPTFTLNFSR PGNQVVGQYY NFLRLGRDGY TKVMQALSHT ARWLGDQLRE 370 380 390 400 410 420 VDHCEVISDG SAIPVVSFRL AGDRGYTEFD VSHELRTFGW QVPAYTMPDN ATDVAVLRIV 430 440 450 460 VREGLSADLA RALHDDAVTA LAALDKVKPG GHFDAQHFAH

References

[1]	"Whole-Genome Sequences of Two Clinical Isolates of Mycobacterium tuberculosis from Kerala, South India." Madhavilatha G.K., Joseph B.V., Paul L.K., Kumar R.A., Hariharan R., Mundayoor S. J. Bacteriol. 194:4430-4430(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: RGTB423 EMBL AFE14550.1.
[2]	Madhavilatha K.G., Joseph B.V., Paul L.K., Kumar A.R., Hariharan R., Mundayoor S. Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: RGTB423 EMBL AFE14550.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003234 Genomic DNA. Translation: AFE14550.1.
RefSeq	YP_005924546.1. NC_017528.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AFE14550; AFE14550; MRGA423_21620.
GeneID	12514391.
KEGG	mti:MRGA423_21620.
Phylogenomic databases
KO	K01580.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

H8I0H1_MYCTU

Accession

Primary (citable) accession number: H8I0H1

Entry history

Integrated into UniProtKB/TrEMBL:	May 16, 2012
Last sequence update:	May 16, 2012
Last modified:	April 3, 2013
This is version 7 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)