Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

H8HHL7

- H8HHL7_STRPY

UniProt

H8HHL7 - H8HHL7_STRPY

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus pyogenes MGAS1882
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 13 (01 Oct 2014)
      Sequence version 1 (16 May 2012)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei150 – 1501UniRule annotation
    Active sitei595 – 5951UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciSPYO1010840:GLLF-528-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotationImported
    ORF Names:MGAS1882_0528Imported
    OrganismiStreptococcus pyogenes MGAS1882Imported
    Taxonomic identifieri1010840 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000008017: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H8HHL7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIEETSKEGD GHLPLKKLES SNNQAIIAEE VALLKEMLEN ITRRMIGDDA    50
    FTVIESIMVL SEKQDYIELE KVVANISNQE MEVISRYFSI LPLLINISED 100
    VDLAYEINYQ NNTNTDYLGK LALTIKDLAG KDNGKDILEQ VNVVPVLTAH 150
    PTQVQRKTIL ELTTHIHKLL RKYRDAKAGV INLEKWRQEL YRYIEMIMQT 200
    DIIREKKLQV KNEIKNVMQY YDGSLIQAVT KLTTEYKNLA QKHGLELDNP 250
    KPITMGMWIG GDRDGNPFVT AETLCLSATV QSEVILNYYI DKLAALYRTF 300
    SLSSTLVQPN SEVERLASLS QDQSIYRGNE PYRRAFHYIQ SRLKQTQIQL 350
    TNQPAARMSS SVGLNTSAWS SPASLENPIL AYDSPVDFKA DLKAIEQSLL 400
    DNGNSALIEG DLREVMQAVD IFGFFLASID MRQDSSVQEA CVAELLKGAN 450
    IVDDYSSLSE TEKCDVLLQQ LMEEPRTLSS AAVAKSDLLE KELAIYTTAR 500
    ELKDKLGEEV IKQHIISHTE SVSDMFELAI MLKEVGLVDQ QRARVQIVPL 550
    FETIEDLDNA RDIMAAYLSH DIVKSWIATN RNYQEIMLGY SDSNKDGGYL 600
    ASGWTLYKAQ NELTSIGEEH GVKITFFHGR GGTVGRGGGP SYDAITSQPF 650
    GSIKDRIRLT EQGEIIENKY GNKDVAYYHL EMLISASINR MVTQMITDPN 700
    EIDSFREIMD SIVADSNTIY RKLVFDNPHF YDYFFEASPI KEVSSLNIGS 750
    RPAARKTITE ITGLRAIPWV FSWSQNRIMF PGWYGVGSAF KRYIDRAQGN 800
    LERLQHMYQT WPFFHSLLSN VDMVLSKSNM NIAFQYAQLA ESQDVRDVFY 850
    EILDEWQLTK NVILAIQDHD DLLEDNPSLK HSLKSRLPYF NVLNYIQIEL 900
    IKRWRNNQLD ENDEKLIHTT INGIATGLRN SG 932
    Length:932
    Mass (Da):106,006
    Last modified:May 16, 2012 - v1
    Checksum:iCDDBDADB3E6825A6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003121 Genomic DNA. Translation: AFC67751.1.
    RefSeqiWP_014407425.1. NC_017053.1.
    YP_005411282.1. NC_017053.1.

    Genome annotation databases

    EnsemblBacteriaiAFC67751; AFC67751; MGAS1882_0528.
    GeneIDi12013816.
    KEGGistx:MGAS1882_0528.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003121 Genomic DNA. Translation: AFC67751.1 .
    RefSeqi WP_014407425.1. NC_017053.1.
    YP_005411282.1. NC_017053.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFC67751 ; AFC67751 ; MGAS1882_0528 .
    GeneIDi 12013816.
    KEGGi stx:MGAS1882_0528.

    Phylogenomic databases

    KOi K01595.

    Enzyme and pathway databases

    BioCyci SPYO1010840:GLLF-528-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Full-Genome Dissection of an Epidemic of Severe Invasive Disease Caused by a Hypervirulent, Recently Emerged Clone of Group A Streptococcus."
      Fittipaldi N., Beres S.B., Olsen R.J., Kapur V., Shea P.R., Watkins M.E., Cantu C.C., Laucirica D.R., Jenkin L., Flores A.R., Lovgren M., Ardanuy C., Linares J., Low D.E., Tyrrell G.J., Musser J.M.
      Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MGAS1882Imported.

    Entry informationi

    Entry nameiH8HHL7_STRPY
    AccessioniPrimary (citable) accession number: H8HHL7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 16, 2012
    Last sequence update: May 16, 2012
    Last modified: October 1, 2014
    This is version 13 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3