Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Superoxide dismutase

Gene

sodA

Organism
Streptococcus pyogenes MGAS1882
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: InterPro
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Enzyme and pathway databases

BioCyciSPYO1010840:GLLF-1079-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sodAImported
ORF Names:MGAS1882_1079Imported
OrganismiStreptococcus pyogenes MGAS1882Imported
Taxonomic identifieri1010840 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008017: Chromosome

Structurei

3D structure databases

ProteinModelPortaliH8HEU0.
SMRiH8HEU0. Positions 5-197.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

KOiK04564.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H8HEU0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAIILPELPY AYDALEPQFD AETMTLHHDK HHATYVANTN AALEKHPEIG
60 70 80 90 100
ENLEELLADV TKIPEDIRQA LINNGGGHLN HALFWELLSP EKQDVTSDVA
110 120 130 140 150
QAIDDAFGSF DAFKEQFTAA ATGRFGSGWA WLVVNKEGQL EITSTANQDT
160 170 180 190 200
PISEGKKPIL ALDVWEHAYY LNYRNVRPNY IKAFFEIINW KKVSELYQAA

K
Length:201
Mass (Da):22,657
Last modified:May 16, 2012 - v1
Checksum:i74F066CA96477050
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003121 Genomic DNA. Translation: AFC68286.1.
RefSeqiYP_005411818.1. NC_017053.1.

Genome annotation databases

EnsemblBacteriaiAFC68286; AFC68286; MGAS1882_1079.
GeneIDi12014911.
KEGGistx:MGAS1882_1079.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003121 Genomic DNA. Translation: AFC68286.1.
RefSeqiYP_005411818.1. NC_017053.1.

3D structure databases

ProteinModelPortaliH8HEU0.
SMRiH8HEU0. Positions 5-197.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFC68286; AFC68286; MGAS1882_1079.
GeneIDi12014911.
KEGGistx:MGAS1882_1079.

Phylogenomic databases

KOiK04564.

Enzyme and pathway databases

BioCyciSPYO1010840:GLLF-1079-MONOMER.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Full-Genome Dissection of an Epidemic of Severe Invasive Disease Caused by a Hypervirulent, Recently Emerged Clone of Group A Streptococcus."
    Fittipaldi N., Beres S.B., Olsen R.J., Kapur V., Shea P.R., Watkins M.E., Cantu C.C., Laucirica D.R., Jenkin L., Flores A.R., Lovgren M., Ardanuy C., Linares J., Low D.E., Tyrrell G.J., Musser J.M.
    Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MGAS1882Imported.

Entry informationi

Entry nameiH8HEU0_STRPY
AccessioniPrimary (citable) accession number: H8HEU0
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: February 4, 2015
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.