Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

H8H6L2 (H8H6L2_HELPX) Unreviewed, UniProtKB/TrEMBL

Last modified January 22, 2014. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
ORF Names:HPELS_00125 EMBL AFF19613.1
OrganismHelicobacter pylori ELS37 [Complete proteome] EMBL AFF19613.1
Taxonomic identifier1055527 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length425 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
H8H6L2 [UniParc].

Last modified May 16, 2012. Version 1.
Checksum: 582BAE84B00CE74A

FASTA42547,478
        10         20         30         40         50         60 
MAYNPKILQK PKEGEEITIK DNKLHVPNHP IIPFIEGDGI GSDITPAMIK VVDSAVQKAY 

        70         80         90        100        110        120 
KGEKKIAWYE VFVGEKCYQK FKDHKELSPE EQWLLPDTIE AINHYKVSIK GPLTTPIGEG 

       130        140        150        160        170        180 
FRSLNVALRQ KMDLYVCLRP VRWYGSPSPV KEPQKVDMVI FRENSEDIYA GIEWQEGSAE 

       190        200        210        220        230        240 
AKKLIHFLQN ELKVKKIRFP ESSGVGIKPI SKEGTERLVR KAIEYAIDND KPSVTFVHKG 

       250        260        270        280        290        300 
NIMKYTEGAF MKWGYALAQK EFNAQVIDKG PWCSLKNPKT GKEIIIKDMI ADAFLQQILL 

       310        320        330        340        350        360 
RPSEYSVIAT MNLNGDYVSD ALAAMVGGIG IAPGANLNDT VGMFEATHGT APKYAGLDKV 

       370        380        390        400        410        420 
NPGSIILSAE MMLRHMGWVE AADLIVSAME KAIKSKKVTY DFARLMDGAK EVKCSEFASV 


MIENM 

« Hide

References

[1]Bertoli M.T., Kersulyte D., Pascasio M.A., Berg D.E.
Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: ELS37 EMBL AFF19613.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002953 Genomic DNA. Translation: AFF19613.1.
RefSeqYP_005424189.1. NC_017063.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFF19613; AFF19613; HPELS_00125.
GeneID12019295.
KEGGhpe:HPELS_00125.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Enzyme and pathway databases

BioCycHPYL1055527:GLEB-28-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH8H6L2_HELPX
AccessionPrimary (citable) accession number: H8H6L2
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: January 22, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)