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H8GVQ6 (H8GVQ6_DEIGI) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL AFD25618.1
Ordered Locus Names:DGo_CA1691 EMBL AFD25618.1
OrganismDeinococcus gobiensis (strain DSM 21396 / JCM 16679 / CGMCC 1.7299 / I-0) [Complete proteome] [HAMAP] EMBL AFD25618.1
Taxonomic identifier745776 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
H8GVQ6 [UniParc].

Last modified May 16, 2012. Version 1.
Checksum: B7395F9A856F0A7A

FASTA41945,825
        10         20         30         40         50         60 
MTSHIKVPAQ GEKITMQGDK LQVPAQPIIP FVEGDGTGRD IWKASVRVLD AAVEAAYGNE 

        70         80         90        100        110        120 
RKIEWLEVYA GEKSTQVYGE NEWLPDETVK AFDEYLIGIK GPLTTPVGGG IRSINVALRQ 

       130        140        150        160        170        180 
LLDLYACLRP VQYFAGVPSP LKQPELVDMV IFRENTEDIY AGIEYKAGTA EANKLRDFLI 

       190        200        210        220        230        240 
NEMGVTQIRF PDSSSLGVKP VSKEGTERLV RAAIQYAIDN GRKSVTLVHK GNIMKFTEGG 

       250        260        270        280        290        300 
FRDWGYDLAK REFGGVELDG GPWLQLPNGI VIKDVIADAF LQQILLRPAE YDVIATLNLN 

       310        320        330        340        350        360 
GDYVSDALAA QVGGIGIAPG ANINYVTGHA IFEATHGTAP KYADKNVINP SSVILSGEMM 

       370        380        390        400        410 
LRHMGWTEAA DLILKGLDQT IGQKVVTYDF ARNMEGATEV KTSEFADKII ENMKAMAQA 

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References

[1]"Genome Sequence and Transcriptome Analysis of the Radioresistant Bacterium Deinococcus gobiensis: Insights into the Extreme Environmental Adaptations."
Yuan M., Chen M., Zhang W., Lu W., Wang J., Yang M., Zhao P., Tang R., Li X., Hao Y., Zhou Z., Zhan Y., Yu H., Teng C., Yan Y., Ping S., Wang Y., Lin M.
PLoS ONE 7:E34458-E34458(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 21396 / JCM 16679 / CGMCC 1.7299 / I-0.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002191 Genomic DNA. Translation: AFD25618.1.
RefSeqYP_006261076.1. NC_017790.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFD25618; AFD25618; DGo_CA1691.
GeneID12814413.
KEGGdgo:DGo_CA1691.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Enzyme and pathway databases

BioCycDGOB745776:GLCE-1740-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH8GVQ6_DEIGI
AccessionPrimary (citable) accession number: H8GVQ6
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: April 16, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)